The effectiveness of non-Invasive ventilation in Covid-19 patients
Keywords:
COVID-19, NIV, Non-invasive ventilation, hypoxemia, respiratory failure, intubation, positive pressureAbstract
Background: Endotracheal intubation is avoided more often with noninvasive ventilation (NIV) in COVID-19 patients with hypoxemia. An endotracheal or tracheostomy tube is not required to use the NIV to deliver mechanical ventilation. When inflating the lungs for oxygenation, positive pressure is provided directly to the airway while negative pressure is applied externally to the abdomen and thorax to draw air into the lungs. Methods: The study was using a quasi-experimental (single-group pre- and post-test design) and sequential sampling approach. Patients hospitalised to the corona complex at LRH-MTI in Peshawar and who tested positive for COVID 19 PCR were selected for the study. Results: There were 34.8 percent of people in the study between the ages of 30 and 45, 38.5 percent between the ages of 46 and 60, and 26.2 percent between the ages of 61 and 75. Co-infections with a positive COVID-19 PCR were found in 47.8% (66) of patients. Overall, 53.6% of patients showed significant improvement after receiving NIV and were subsequently released. For 46.4% of these patients, the NIV did not work, leading to intubation or death. Co-existing diseases were present in the majority of individuals whose NIV attempts were unsuccessful.
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Zhou A, Song Q, Peng Y, Deng D, Liao X, Huang P, et al. The Effect of Noninvasive Ventilation Support on COVID-19 Patients and Risk Factors for Invasive Ventilation–A Retrospective and Multicenter Study. Int J Gen Med. 2021;14:6085.
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The lancet. 2020;395(10223):497-506.
Al-Rawahi B, Prakash K, Al-Wahaibi A, Al-Jardani A, Al-Harthy K, Kurup PJ, et al. Epidemiological characteristics of pandemic coronavirus disease (COVID-19) in Oman. Sultan Qaboos Univ Med J. 2021;21(2):e195.
Attaway AH, Scheraga RG, Bhimraj A, Biehl M, Hatipoğlu U. Severe covid-19 pneumonia: pathogenesis and clinical management. BMJ. 2021;372.
Qasim M, Ahmad W, Zhang S, Yasir M, Azhar M. Data model to predict prevalence of COVID-19 in Pakistan. MedRxiv. 2020.
Wan S, Xiang Y, Fang W, Zheng Y, Li B, Hu Y, et al. Clinical features and treatment of COVID‐19 patients in northeast Chongqing. J Med Virol. 2020;92(7):797-806.
Yang X, Yu Y, Xu J, Shu H, Liu H, Wu Y, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. The Lancet Respiratory Medicine. 2020;8(5):475-81.
Jiang B, Wei H. Oxygen therapy strategies and techniques to treat hypoxia in COVID-19 patients. Eur Rev Med Pharmacol Sci. 2020;24(19):10239-46.
Ayyaz S, Javaid A, Hanif A, Nasir Y, Qureshi A, Ahmed S, et al. Effectiveness of Noninvasive Positive Pressure Ventilation in COVID-19 Patients with Severe Acute Respiratory Distress Syndrome. Annals of King Edward Medical University. 2021;27(2).
Scala R, Pisani L. Noninvasive ventilation in acute respiratory failure: which recipe for success? European respiratory review. 2018;27(149).
Menzella F, Barbieri C, Fontana M, Scelfo C, Castagnetti C, Ghidoni G, et al. Effectiveness of noninvasive ventilation in COVID‐19 related‐acute respiratory distress syndrome. The clinical respiratory journal. 2021.
Avdeev SN, Yaroshetskiy AI, Tsareva NA, Merzhoeva ZM, Trushenko NV, Nekludova GV, et al. Noninvasive ventilation for acute hypoxemic respiratory failure in patients with COVID-19. The American journal of emergency medicine. 2021;39:154-7.
Bertaina M, Nuñez-Gil IJ, Franchin L, Rozas IF, Arroyo-Espliguero R, Viana-Llamas MC, et al. Non-invasive ventilation for SARS-CoV-2 acute respiratory failure: a subanalysis from the HOPE COVID-19 registry. Emergency Medicine Journal: EMJ. 2021.
Daniel P, Mecklenburg M, Massiah C, Joseph MA, Wilson C, Parmar P, et al. Non-invasive positive pressure ventilation versus endotracheal intubation in treatment of COVID-19 patients requiring ventilatory support. The American journal of emergency medicine. 2021;43:103-8.
Fang W, Zheng Y, Li B, Hu Y, et al. Clinical features and treatment of COVID‐19 patients in northeast Chongqing. J Med Virol. 2020;92(7):797-806
Pisani L. Noninvasive ventilation in acute respiratory failure: which recipe for success? European respiratory review. 2018;27(149).
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