Efficacy of oral fluconazole versus oral terbinafine in the treatment of tinea capitis
Keywords:
diflucan, fluconazole, lamisil, terbinafine, tinea capitisAbstract
Objective: To compare the effectiveness of oral Fluconazole vs oral Terbinafine in the treatment of tinea capitis. Place and Duration: This Randomized control trial was conducted from 6th December, 2019 to 6th June, 2020 in the Department of Dermatology, Hayatabad Medical Complex, Peshawar. Subject and Method: The study was carried out at Department of Dermatology, Hayatabad Medical Complex Peshawar. Through consecutive sampling technique, all patients meeting the diagnostic requirements for inclusion were selected from the OPD. The parents or guardians of the patients provided written informed consent and were advised that the information would be kept confidential because it was all done only for the purpose of the study. To confirm Tinea Capitis in all patients, a thorough history, physical examination, and microscopy were performed. Through the use of a lottery, patients were randomly split into Group A and Group B. For four weeks, patients in Group A received Fluconazole 6–8 mg/kg once weekly. Terbinafine 3-5 mg/kg was given once daily to patients in Group B. Patients were evaluated using the Total Sign and Symptom Score (TSSS) and microscopic inspection at the time of study enrolment, as well as at 4- and 8-week intervals after those times.
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