Gynecological disorders as factors that could cause cervical neoplasia
Keywords:
gynecological disorders, human papillomavirus, cervical neoplasia, trichomonas vaginalis, preinvasive lesions, cancer, herpes simplex virusAbstract
A longitudinal cohort research was conducted to see if gynaecological disorders besides the human papillomavirus (HPV) remain associated to the elevated threat to cervical neoplasia. The research included many women who participated in the planned mass screening. Trichomonas vaginalis and HPV, respectively, remained linked through a significant comparative probability of preinvasive lesions, cervical cancer and invasive cancer merged, and preinvasive lesions and invasive cancer combined. Despite its rarity in detection, the greatest and theoretically highly meaningful information system provides for Herpes simplex virus (HSV) was discovered. It was not demonstrated that actinomyces or yeast significantly increased the cervical cancer risk. The other illnesses' confounding effects were unable to explain any of these findings. This led us to propose that the herpes simplex virus and Trichomonas vaginalis are further cervical neoplasia predictors.
Downloads
References
Bjørge, T., Hjellvik, V., Bjørge, L., dos‐Santos‐Silva, I., Furu, K., Kvåle, R., & Engeland, A. (2023). Incidence and prevalence of drugs used for chronic diseases in survivors of adult‐onset gynaecological cancer‐a nationwide cohort study. BJOG: An International Journal of Obstetrics & Gynaecology.
Chan, C. K., Aimagambetova, G., Ukybassova, T., Kongrtay, K., & Azizan, A. (2019). Human papillomavirus infection and cervical cancer: epidemiology, screening, and vaccination—review of current perspectives. Journal of oncology, 2019.
Dattner, A. M. (2022). Herbal and Integrative Medicine-Associated Improvement of Viral-Induced Cervical and Vaginal Disorders: Case Report. Integrative Medicine Reports, 1(1), 235-239.
Gholizadeh, O., Yekanipour, Z., Kivi, S., Farahbod, F., Aqayinejad, M., Tasoujizade, Y., ... & Poortahmasebi, V. (2023). Review of the evidence of the effects of human papillomavirus infection and Gardnerella vaginalis, and their co-infection on infertility. Microbial Pathogenesis, 105980.
Gurumurthy, R. K., Koster, S., Kumar, N., Meyer, T. F., & Chumduri, C. (2022). Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection. Nature Protocols, 17(7), 1658-1690.
Horsboel, T. A., Kjaer, S. K., Johansen, C., Suppli, N. P., Ammitzbøll, G., Frøding, L. P., ... & Dalton, S. O. (2019). Increased risk for depression persists for years among women treated for gynecological cancers-a register-based cohort study with up to 19 years of follow-up. Gynecologic Oncology, 153(3), 625-632.
Kudela, E., Holubekova, V., Kolkova, Z., Kasubova, I., Samec, M., Mazurakova, A., & Koklesova, L. (2023). Vaginal Microbiome and Its Role in HPV Induced Cervical Carcinogenesis. In Microbiome in 3P Medicine Strategies: The First Exploitation Guide (pp. 43-86). Cham: Springer International Publishing.
Macios, A., Didkowska, J., Wojciechowska, U., Komerska, K., Glińska, P., Kamiński, M. F., & Nowakowski, A. (2021). Risk factors of cervical cancer after a negative cytological diagnosis in Polish cervical cancer screening programme. Cancer Medicine, 10(10), 3449-3460.
Mogavero, M. P., DelRosso, L. M., Fanfulla, F., Bruni, O., & Ferri, R. (2021). Sleep disorders and cancer: State of the art and future perspectives. Sleep Medicine Reviews, 56, 101409.
Mohamed, H. E. A. (2019). Evaluation of prognostic markers for oropharyngeal carcinoma using tissue microarray. Dissertationes Scholae Doctoralis Ad Sanitatem Investigandam Universitatis Helsinkiensis.
Plisko, O., Zodzika, J., Jermakova, I., Pcolkina, K., Prusakevica, A., Liepniece-Karele, I., ... & Rezeberga, D. (2021). Aerobic vaginitis—underestimated risk factor for cervical intraepithelial neoplasia. Diagnostics, 11(1), 97.
Tarapan, S., Matangkasombut, O., Trachootham, D., Sattabanasuk, V., Talungchit, S., Paemuang, W., ... & Lam‐ubol, A. (2019). Oral Candida colonization in xerostomic postradiotherapy head and neck cancer patients. Oral Diseases, 25(7), 1798-1808.
Vallianou, N., Kounatidis, D., Christodoulatos, G. S., Panagopoulos, F., Karampela, I., & Dalamaga, M. (2021). Mycobiome and cancer: what is the evidence?. Cancers, 13(13), 3149.
Wei, W., Xie, L. Z., Xia, Q., Fu, Y., Liu, F. Y., Ding, D. N., & Han, F. J. (2022). The role of vaginal microecology in the cervical cancer. Journal of Obstetrics and Gynaecology Research, 48(9), 2237-2254.
Wu, C. T., Chiu, L. T., & Raturi, V. P. (2023). Investigation of the Correlation Between Mental Disorder and Cervical Cancer in Taiwan: A Nationwide Population-Based Cohort Study. Indian Journal of Gynecologic Oncology, 21(1), 29.
Published
How to Cite
Issue
Section
Copyright (c) 2023 International journal of health sciences

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.








