Frequency of common bile duct strictures in patients presenting with obstructive jaundice in Ayub teaching hospital

https://doi.org/10.53730/ijhs.v6nS10.14098

Authors

  • Zabih Ullah Assist Prof Gastroenterology Ward Ayub Medical College & Teaching Hospital Abbottabad, Pakistan
  • Rania Hidayat Consultant Gastroenterology Ward Ayub Teaching Hospital Abbottabad, Pakistan
  • Ummarah Riaz Registrar Gastroenterology Ward Ayub Teaching Hospital Abbottabad, Pakistan
  • Hafizullah Khan Medical Officer Gastroenterology Ward Ayub Teaching Hospital Abbottabad, Pakistan
  • Adil Naseer Prof Gastroenterology Ward Ayub Medical College & Teaching Hospital Abbottabad, Pakistan
  • Shawana Asad Assistant Professor Surgical Ward.Ayub Teaching Hospital Abbottabad, Pakistan

Keywords:

obstructive jaundice, common bile duct strictures, frequency

Abstract

Background; Obstructive jaundice in simple terms means the outflow of bile has been obstructed anywhere from the liver to the duodenum. It is caused by obstruction, blockage and/or compression of common bile duct (CBD) and/or biliary tract that leads to incomplete excretion of bile into the intestine. Patients with obstructive jaundice usually present with Complains of abdominal pain, yellow discoloration of skin and/or eyes, pale stools, dark colored urine, nausea, vomiting and pruritus. Objective: To determine frequency of common bile duct strictures in patients presenting with obstructive jaundice in Ayub teaching hospital. Material and Method.  This Cross Sectional Study was conducted in the department of Gastroenterology, ATH, Abbottabad from 15th September 2020 to 15th March 2021. A total of 135 patients of both gender presenting with jaundice and having serum bilirubin ≥1.1 mg/dl, alkaline phosphatase ≥140 IU/L along with evidence of obstruction of common bile duct were included in the study. Presence of CBD stricture was confirmed through Ultrasonography or CT abdomen. Results: Age range in this study was from 20 to 80 years with mean age of 44.651±12.90 years. Female gender was dominant with 61.5% patients. Common bile duct strictures was seen in 9.6% patients. 

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References

Khan ZA. Clinical profile of patients with obstructive jaundice: a surgeon's perspectives. Int Surg J. 2019;6(6):1876-80

Bhanbhro RJ, Maheshwari T, Jarwar M. Etiological pattern and early outcome of patients presenting with obstructive jaundice at Isra University Hospital, Hyderabad, Pakistan. Rawal Medical J. 2018;43(1):68-74.

Kurian JM, John PK, Ganesh K, Hegde P,Murthy C, Kumar A. Assessment of clinical profile of patients with obstructive jaundice. Int J Contemp Med Res 2017;4(1):197-200.

Altman A, Zangan SM. Benign biliary strictures. Semin intervent rad 2016 33(4);297- 306.

Ma MX, Jayasekeran V, Chong AK. Benign biliary strictures :prevalence, impact, and management strategies. Clin. Exp. Gastroenterol.;12:83-92

Salgado SM, Gaidhane M, Kahaleh M. Endoscopic palliation of malignant biliary strictures. World J Gastro Oncol. 2016;8(3):240.

Munir K, Bari V, Yaqoob J, Khan DBA, Usman MU. Role of magnetic resonance cholangio-pancreatography (MRCP) in obstructive jaundice. J Pak Med Assoc 2004; 54: 128-32.

Iannicceli E, Sessa A, Argnani L, Galluzzo A, David V. [Role of MR Cholangiopancreatography in the evaluation of biliary disease]. Clin Ter 2006; 157: 425-9.

Ryan S, McNicholas M. The Abdomen: Anatomy for diagnostic imaging. 2nd ed. Philadelphia: WB Saunders, 2004; pp 176-80

Iqbal J, Khan Z, Afridi FG, Alam AWJ, Alam M, Zarin M, et al.Causes of obstructive jaundice. Pak J Surg. 2008;24(1):12-4.

Kim HJ, Kim MH, Myung SJ, et al. A new strategy for the application of CA19-9 in the differentiation of pancreaticobiliary cancer: analysis using a receiver operating characteristic curve. Am J Gastroenterol 1999;94:1941–6.

Rana SS, Bhasin DK, Sharma V, et al. Role of endoscopic ultrasound in evaluation of unexplained common bile duct dilatation on magnetic resonance cholangiopancreatography. Ann Gastroenterol 2013;26:66–70.

Marrelli D, Caruso S, Pedrazzani C, et al. CA19-9 serum levels in obstructive jaundice: clinical value in benign and malignant conditions. Am J Surg 2009;198:333–9.

Gianninie E, Borro P, Botta F, et al. Cholestasis is the main determinant of abnormal CA 19-9 levels in patients with liver cirrhosis. Int J Biol Markers 2000;15:226–30.

Ferrone CR. Perioperative CA19-9 levels can predict stage and survival in patients with resectable pancreatic adenocarcinoma. J Clin Oncol 2006;24:2897–902.

Mihmanli M, Dilege E, Demir U, et al. The use of tumor markers as predictors of prognosis in gastric cancer. Hepatogastroenterology 2004;51:1544–7.

Nehls O, Gregor M, Klump B. Serum and bile markers for cholangiocarcinoma. Semin Liver Dis 2004;24:139–54.

Liu L, Wang J, Liu B, et al. Serum levels of variants of transthyretin down-regulation in cholangiocarcinoma. J Cell Biochem 2008;104:745–55.

Cheon YK, Cho YD, Moon JH, et al. Diagnostic utility of interleukin-6 (IL-6) for primary bile duct cancer and changes in serum IL-6 levels following photodynamic therapy. Am J Gastroenterol 2007;102:2164–70.

Silsirivanit A, Araki N, Wongkham C, et al. A novel serum carbohydrate marker on mucin 5AC: values for diagnostic and prognostic indicators for cholangiocarcinoma. Cancer 2011;117:3393–403.

Leelawat K, Narong S, Wannaprasert J, et al. Prospective study of MMP7 serum levels in the diagnosis of cholangiocarcinoma. World J Gastroenterol. 2010;16:4697–703.

Gupta V,Jain G, Safe laparoscopic cholecystectomy: Adoption of universal culture of safety in cholecystectomy. World journal of gastrointestinal surgery. 2019 Feb

Published

26-03-2023

How to Cite

Ullah, Z., Hidayat, R., Riaz, U., Khan, H., Naseer, A., & Asad, S. (2023). Frequency of common bile duct strictures in patients presenting with obstructive jaundice in Ayub teaching hospital. International Journal of Health Sciences, 6(S10), 1567–1573. https://doi.org/10.53730/ijhs.v6nS10.14098

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