Insight into the molecular pathogenesis of odontogenic tumours
Keywords:
ameloblastoma, molecular profiling, odontogenic cysts, odontogenic tumorsAbstract
Odontogenic tumors, derived from epithelial, ectomesenchymal, and/or mesenchymal elements of the tooth-forming apparatus, constitute a heterogeneous group of lesions, including hamartomas, benign and malignant neoplasms with metastatic capabilities. This review provides a comprehensive overview of the molecular events in the pathogenesis of odontogenic tumors. The reasonable and better understanding of the molecular components may prompt new ideas for their detection and administrating a better prognosis of odontogenic tumors.
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