Cytopathological evaluation of thyroid by fine needle aspiration cytology and its association with thyroid function

https://doi.org/10.53730/ijhs.v7nS1.14160

Authors

  • Mohammad Noman Yousaf Trainee Registrar, Chemical Pathology, CMH Peshawar
  • Hanif Ullah District ENT Specialist Cat C Hospital Wari Dir Upper, MBBS (KMU), FCPS otorhinolaryngology
  • Muhammad Farooq MBBS, FCPS (General Surgery), Surgical Department, cat-D Hospital Munda
  • Maria Oubaid Department of life Sciences, School of Science University of Management and Technology Lahore
  • Col. Sajida Shaheen Consultant, Chemical Pathology, CMH Peshawar
  • Munir Hussain Assistant Professor, Chemical Pathology, CMH Peshawar
  • Afsheen Bashir Senior Medical Office Naseerudin Babar Hospital Peshawar
  • Ushna Gul Khyber Teaching Hospital Peshawar
  • Ravi Dutt Sharma Assistant Professor-Biology, Department of Biology, College of Engineering, Science and Technology, Natabua Campus, Lautoka, Fiji National University

Keywords:

thyroid, goiter, biopsy, fine needle aspiration, thyroid function, thyroid-stimulating hormone (TSH)

Abstract

Introduction: Fine needle aspiration cytology is a reliable method for thyroid nodule evaluation (FNAC). Thyroid nodules often cause abnormal thyroid function tests, which are used for diagnosis and therapy. Thyroid cancer and incorrect thyroid function testing are still debated. Objective: We aimed to evaluate the cytopathological features of thyroid nodules by FNAC and their association with thyroid function tests. Methods: This 12-month cross-sectional study was conducted in Peshawar, Pakistan. 350 thyroid nodule patients were referred to endocrinology. All research participants had a physical checkup and thyroid function testing. Thyroid function testing measured TSH and FT4 using conventional laboratory procedures. All individuals had 23-gauge ultrasound-guided thyroid nodule FNAC. Pathologists used the Bethesda System for Reporting Thyroid Cytopathology to evaluate FNAC samples. SPSS 25 analyzed the data. Descriptive statistics detailed the study population's clinical and demographic characteristics. Logistic regression was utilized to examine the relationship between thyroid function tests and thyroid cancer risk and FNAC's thyroid cancer detection effectiveness. Results: For this research, a total of 350 thyroid nodule patients were included having the median age 39.8 (20-60) years and the ratio of female to male participants was 3:1. 

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References

Ahmed, I., Ali, L., & Khan, A. (2018). Fine-needle aspiration cytology of thyroid nodules: a study of 1,008 cases. Journal of cytology, 35(3), 156.

Al-Ahmary, A. M., & Al-Essa, F. (2017). Thyroid fine-needle aspiration cytology practice in Saudi Arabia: a national survey. Journal of pathology and translational medicine, 51(2), 147-154.

Bongiovanni, M., Spitale, A., Faquin, W. C., Mazzucchelli, L., & Baloch, Z. W. (2012). The Bethesda System for Reporting Thyroid Cytopathology: a meta-analysis. Acta cytologica, 56(4), 333-339.

Ho, A. S., Sarti, E. E., Jain, K. S., Wang, H., Nixon, I. J., Shaha, A. R., ... & Tuttle, R. M. (2018). Malignancy rate in thyroid nodules classified as Bethesda category III (AUS/FLUS). Thyroid, 28(7), 896-905.

Kumar, S., & Shah, S. R. (2017). Evaluation of thyroid nodules by fine-needle aspiration cytology: correlation with clinical, biochemical, and radiological findings. Journal of cytology, 34(2), 75.

Ahmed, I., Ali, L., & Khan, A. (2018). Fine-needle aspiration cytology of thyroid nodules: a study of 1,008 cases. Journal of cytology, 35(3), 156.

Al-Ahmary, A. M., & Al-Essa, F. (2017). Thyroid fine-needle aspiration cytology practice in Saudi Arabia: a national survey. Journal of pathology and translational medicine, 51(2), 147-154.

Bongiovanni, M., Spitale, A., Faquin, W. C., Mazzucchelli, L., & Baloch, Z. W. (2012). The Bethesda System for Reporting Thyroid Cytopathology: a meta-analysis. Acta cytologica, 56(4), 333-339.

Kumar, S., & Shah, S. R. (2017). Evaluation of thyroid nodules by fine-needle aspiration cytology: correlation with clinical, biochemical, and radiological findings. Journal of cytology, 34(2), 75.

Ho, A. S., Sarti, E. E., Jain, K. S., Wang, H., Nixon, I. J., Shaha, A. R., ... & Tuttle, R. M. (2018). Malignancy rate in thyroid nodules classified as Bethesda category III (AUS/FLUS). Thyroid, 28(7), 896-905.

Published

15-04-2023

How to Cite

Yousaf, M. N., Ullah, H., Farooq, M., Oubaid, M., Shaheen, C. S., Hussain, M., Bashir, A., Gul, U., & Sharma, R. D. (2023). Cytopathological evaluation of thyroid by fine needle aspiration cytology and its association with thyroid function. International Journal of Health Sciences, 7(S1), 104–110. https://doi.org/10.53730/ijhs.v7nS1.14160

Issue

Vol. 7 No. S1 (2023)

Section

Peer Review Articles
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