Risk factors associated with retinopathy of prematurity

https://doi.org/10.53730/ijhs.v6nS9.14198

Authors

  • Supriya Mushriff Associate Professor, Department of Ophthalmology, Index Medical College and Hospital, Indore
  • Ritika Ranjan Postgraduate Resident 3rd Year, Department of Ophthalmology, Index Medical College and Hospital, Indore
  • Mansi Sarwate Postgraduate Resident 2nd Year, Department of Ophthalmology, Index Medical College and Hospital, Indore

Keywords:

low birth weight, prematurity, awareness, screening, retinopathy of prematurity, prevalence

Abstract

Background: Retinopathy of prematurity (ROP) is an important cause of preventable blindness in children. It is a serious and underestimated complication of prematurity treatment among preterm and low-birth weight babies and is preventable cause of blindness unless recognized and treated early. Objective: Evaluate the different neonatal risk factors for Retinopathy of Prematurity. Materials and Methods: A ROP prospective screening survey was performed enrolling all premature and low-birth-weight Neonates delivered at Index Medical College Hospital & Research Centre from July 2018 to June 2021, with a gestational age of 37 weeks or less at birth and a birth weight of 1700 g or less. One Hundred and Eighty Six (186) preterm infants (i.e.372 eyes) were included for ROP screening. Out of these 186 preterm infants (372eyes), Forty eight (48) preterm infants (i.e.96 eyes) developed Retinopathy of Prematurity. Descriptive statistics included the mean and standard deviation for numerical variables, and the percentage of different categories for categorical variables. Result: In our study, various risk factors are analysed for the disease Retinopathy of Prematurity. This statistical analysis is done by Chi-square test (P-value). 

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References

AIIMS- NICU Protocols 2010, Retinopathy Of Prematurity, Deepak Chawla, Ramesh Agarwal,Ashok Deorari, Vinod K Paul, Parijat Chandra ,RV Azad, Www.Newbornwhocc.Org

American Academy Of Pediatrics Section On Ophthalmology; American Academy Of Ophthalmology; American Association For Pediatric Ophthalmology And Strabismus. Screening Examination Of Premature Infants For Retinopathy Of Prematurity. Pediatr. 2006;117:572–6.

Andruscavage L, Weissgold DJ .Screening For Retinopathy Of Prematurity.Br J Ophthalmol .2002;86:1127-30.

4.Azad R, Trese M T. Text Book Of Retinopathy Of Prematurity.1st Ed. New Delhi:Wolters Kluwer,2011:159

Avery GB, Glass P. Retinopathy Of Prematurity: What Causes It? Clin Perinatal 1988;15(4):917-928.

Shohat M, Reisner SH,Krikler R, Nissencom I,Yossur Y, Ben-Sira I.Retinopathy Of Prematurity: Incidence And Risk Factors. Paediatrics 1983;72:150-163.

Darlow BA, Horwood LJ, Clement RS. Retinopathy Of Prematurity: Risk Factors In A Prospective Population Based Study. Paediatr Perinatal Epidemiol .1992;6:62-80.

Campbell R. Intensive Oxygen Therapy As A Possible Cause Of Retrolental Fibroplasias. Med J Aust. 1951;2:48-50.

Patz A, Hoeck LE And De La Cruz E. Studies On The Effectsof High Oxygen Administration In Retrolental Fibroplasias. Am J Ophthalmol. 1952;35:1248-1253.

Ashton N, Ward B, Serpell G. Role Of Oxygen In Genesis Of Retrolental Fibroplasias. A Preliminary Report. Br J Ophthalmol. 1953;37:513-20

Kinsey VE. Retrolental Fibroplsias: Cooperative Study Of Retrolental Fibroplasias And The Useof Oxygen. Arch Ophthalmol.1956;56:481-543.

Kinsey VE, Arnold HJ, Kalina RE, Stern L, Stahlman M, Odall G, Et,Pao₂ Levels And Retrolental Fibroplasias: A Report Of The Cooperative Study. Paediatrics. 1977;60:655-688.

Lechner D, Kalina RE, Hodson WA. Retrolental Fibroplasias And Factors Influencing Oxygen Transport.Paediatrics .1977;59:916-918.

Shaw JCL: Iron Absorption By Prematureinfants : The Effects Of Transfusion And Iron Supplement On The Serum Ferritin Level. Acta Paediatr Scard. 1982;299(Supp):83-89.

Inder TE, Clemett RS, Austin NC, Graham P,Darlow BA. High Iron Status In Very Low Birth Weight Infants Is Associated With An Increased Risk Of Retinopathy Of Prematurity.J Paediatr .1997;131;541-544.

Hasse L, Eberl W, Schland M, Poets CF.Blood Transfusion: Iron Load And Retinopathy Of Prematurity. Eur J Paediatr. 1997;156:465-470.

Aggarwal R, Deorari AK, Azad RV, Kumar H, Talwar D, Sethi AI. Changing Profile Of Retinopathy Of Prematurity. Trop Paediatr .2002;48:239-242.

Vinekar A, Dogra MR,Sangtam T, Narang A, Gupta A.Retinopathy Of Prematurity In Asian Indian Babies Weighing Greater Than 1250 Grams At Birth: Ten Years Data From A Tertiary Care In A Developing Country. Indian J Ophthalmol. 2007;55:331-6.

Reynolds JD, Hardy RJ, Kennedy KA, Et Al. Lack Of Efficacy Of Light Reduction In Preventing Retinopathy Of Prematurity (LIGHT-ROP) Cooperative Group. N Engl J Med. 1998;338:1572-1576.

Am J Ophthalmol.1998(Feb);125(2):197-203.

Shastry. BS, BD Pendergast, MK Hartzer, X Liu, MT Trese. Identificatio Of Missense Mutations In Thenorrie Disease Gene Associated With Advanced Retinopathy Of Prematurity. Arch Ophthalmol. 1997;115:651-655

Alon T, I Hemo, A Itin, J PeEr, J Stone, E Keshet.Vascular Endothelial Griwth Factorbacts As A Survival Factor For Newly Formed Retinal Vessels And Has Implications For Retinopathy Of Prematurity. Nat Med.1995;1:1024-1028

Published

27-06-2022

How to Cite

Mushriff, S., Ranjan, R., & Sarwate, M. (2022). Risk factors associated with retinopathy of prematurity. International Journal of Health Sciences, 6(S9), 4895–4909. https://doi.org/10.53730/ijhs.v6nS9.14198

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