Efficacy of single-versus split-dose polyethylene glycol for colonic preparation: A randomized control study

Taimur Khan; Akkash Haider; Umair Latif; Shahbaz Gul; Fahad Shaheen; Abbas Khan

doi:10.53730/ijhs.v7nS1.14207

Authors

Taimur Khan Senior Registrar and Consultant Gastroenterologist, Department of Medicine and Allied, Rehman Medical Institute Peshawar, Pakistan
Akkash Haider
akkash.haider@yahoo.com
Consultant Gastroenterologist, Department of Medicine and Allied, Fauji Foundation hospital, Peshawar, Pakistan
Umair Latif Consultant Gastroenterologist, Department of Medicine and Allied, Peshawar Institute of Medical Sciences Phase 5 Hayatabad, Peshawar, Pakistan
Shahbaz Gul Consultant Gastroenterologist, RHC Billitang Kohat, Pakistan
Fahad Shaheen Consultant Gastroenterologist, Department of Medicine and Allied, Naseerullah Babar Teaching Hospital Kohat Road Peshawar, Pakistan
Abbas Khan Consultant Gastroenterologist, Deputy Director at Health Directorate General of Health Services KP, Pakistan

Keywords:

polyethylene glycol, colonic preparation, split-dose PEG, colonoscopy

Abstract

Background: Before a colonoscopy, polyethylene glycol (PEG) is often used to prepare the colon. PEG dosage recommendations are still up for discussion. In this randomized controlled experiment, the effectiveness and acceptability of PEG administered in single vs. split doses for colonic preparation was compared. Methods: A total of 120 individuals were randomized to either split-dose PEG for colonic preparation or a single-dose PEG at Department of Gastroenterology, Hayatabad medical complex. The Boston Bowel Preparation Scale (BBPS) was used for assessing the rate of bowel cleaning for the colonoscopy. A visual analog scale was used to evaluate the preparation's acceptability and tolerability. Results: The quality of colonic preparation was considerably greater in the split-dose PEG group than in the single-dose PEG group, as shown by the BBPS score, which was significantly higher in the split-dose PEG group (7.5±1.2) than in the single-dose PEG group (6.3±1.3) (P0.001). Patient satisfaction did not vary significantly between the two groups, but the split-dose PEG group had a higher completion rate of colonoscopies (97% vs. 95%) as well as greater patient acceptability and tolerance.

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