The frequency of gestational diabetes mellitus & its responsible factors among pregnant women presenting at a tertiary care hospital, Karachi

https://doi.org/10.53730/ijhs.v7nS1.14211

Authors

  • Karam -un-Nisa Senior Registrar Gynae & Obs, Liaquat National Hospital, Karachi Pakistan
  • Aisha Taj HOD Gynae & Obs, Liaquat National Hospital, Karachi Pakistan
  • Bakhtawar Dahri Senior Registrar, Gynae & Obs, Liaquat National Hospital, Karachi Pakistan
  • Sajida Senior Registrar, Gynae & Obs, Liaquat National Hospital, Karachi Pakistan
  • Haleema Hashmi Professor, Gynae & Obs, Liaquat National Hospital, Karachi Pakistan
  • Naema Wahid Senior Registrar Gynae & Obs, Badin Indus Hospital, Badin Pakistan

Keywords:

obesity, multiparity, gestational diabetes mellitus

Abstract

Controlling the related factors implicated in the development of GDM may help to mitigate the sharp rise in the prevalence of GDM and its detrimental effects on maternal and newborn problems. Maternal age (over 30 years), prior history of gestational diabetes, increased BMI, family history of diabetes, parity, belonging to an ethnic group with a high correlation with GDM and prior birth of a large baby are the key related factors of GDM. Aim: The main goal is to determine the frequency of gestational diabetes mellitus among pregnant women and its causing factors. Place and Duration: This Descriptive, cross-sectional study was held in Department of Gynecology, Liaquat National Hospital, Karachi from 16th January 2017 to 15th July 2017. Methods: 250 pregnant women with gestational diabetes mellitus between the 18-45 years of age were included. Multiple gestations, unbooked cases, and cases of known DM were not included. Development of gestational diabetes is the primary outcome factor which was determined. Maternal age, parity, gestational age, grand multiparity, BMI (for obesity), prior GDM, prior experience of macrosomic infant, family history of DM & PCOS are additional study variables (responsible factors). 

Downloads

Download data is not yet available.

References

Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, et al. National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 2010: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet. 2019 Jul;378(9785):31-40.

Donath MY, Shoelson SE. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol. 2018 Feb;11(2):98-107.

Metzger BE, Gabbe SG, Persson B, Buchanan TA, Catalano PA, Damm P, et al. International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy. Diabetes Care. 2017; 33:676–82.

Ali S, Dornhorst A. Diabetes in pregnancy: health risks and management. Postgrad Med J. 2017; 87:417 27.

Razaq S, Khan MW, Masood Z, Malik A, Rehaman H, Rehmat N, et al. An investigation on the prevalance of gestational diabetes mellitus in the pregnant women of province Balochistan. World J Med Sci. 2017;12(2):198-203.

Basit A, Hydrie MZ, Hakeem R, Ahmedani MY, Masood Q. Frequency of chronic complications of type II diabetes. J Coll Physicians Surg Pak. 2017; 14:79-83.

Rahman AS, Jaffri MSA, RazaSB, Sattar FA. The prevalence of Gestational Diabetes in patients attending Diabetic clinic at Sir Syed Hospital. Pak J Pharma. 2017 Jan;24(1):37-42.

Lindsay RS. Gestational diabetes: causes and consequences. Br J Diabetes Vasc Dis. 2019; 9:27-31.

Schaefer-Graf UM, Pawliczak J, Passow D. Birth weight and parental BMI predict overweight in children from mothers with gestational diabetes. Diabetes Care. 2015; 28:1745-50.

Tertti K, Ekblad U, Vahlberg T, Ronnemaa T. Comparison of metformin and insulin in the treatment of gestational diabetes: a retrospective, case-control study. Rev Diabet Stud. 2018;5(2):95-101.

Martino J, Sebert S, Segura MT, Garcia-Valdes L, Florido J, Padilla MC, et al. Maternal body weight and gestational diabetes differentially influence placental and pregnancy outcomes. J Clin Endocrinol Metab. 2016 Jan;101(1):59-68.

Iqbal R, Jawaid S, Jabbar A, Qureshi R. Gestational diabetes mellitus-a forerunner of chronic disorders in mother and child. J Pak Med Assoc. 2019;59(7):478-82.

Rai L, Meenakshi D, Kamath A. Metformin: a convenient alternative to insulin for indian women with diabetes in pregnancy. Indian J Med Sci. 201;63(11):491-7.

Tabassam N, Sadaqat F, Mahmood KT, Zaka M. Prevention and management of gestational diabetes. J Pharm Sci Tech. 2017;2(12):404-10.

Shera AS, Jawad F, Maqsood A. Prevalence of diabetes in Pakistan. Diabetes Res Clin Pract. 2017; 76:219-22.

Bibi S, Saleem U, Mahsood N. The frequency of gestational diabetes mellitus and associated risk factors at Khyber teaching hospital Peshawar. J Postgrad Med Inst. 2015;29(1):43-6.

Khan R, Ali K, Khan Z. Socio-demographic risk factors of gestational diabetes mellitus. Pak J Med Sci. 2017;29(3):843-6.

Hashmi A, Soomro JA, Iqbal Z, Soomro TK, Saleem K. Maternal obesity a global health problem and its implications on maternal and fetal health. Reprod Sys Sexual Disord. 2017; 1:103.

Syed W. Obesity related maternal complications in pregnant women. Khyber Med Uni J. 2017;6(3):128-30.

World Health Organization, Western Pacific Region. The International Association for the Study of Obesity and the International Obesity Task Force. The Asia–Pacific perspective: redefining obe-sity and its treatment. Sydney, Australia: Health Communications Australia Pty Limited; 2018: [Cited on January 03, 2018]. Available from URL: www.diabetes.com. au/pdf/obesity_report.pdf

Hoseini SSH, Hantoushzadeh S, Shoar S. Evaluating the extent of pregravid risk factors of gestational diabetes mellitus in women in Tehran. Iran Red Crescent Med J. 2017;13(6):407-14.

Varghese R, Thomas B, Al Hail M, Rauf A, Sadi M, Sualiti A, et al. The prevalence, risk factors, maternal and fetal outcomes in gestational diabetes mellitus Int J Drug Dev Res. Jul-Sept 2016;4(3):356-8.

Baptiste-Roberts K, Barone BB, Gary TL, et al. Risk factors for type 2 diabetes among women with gestational diabetes: a systematic review. Am J Med. 2019 Mar. 122(3):207-214.e4.

Boinpally T, Jovanovic L. Management of type 2 diabetes and gestational diabetes in pregnancy. Mt Sinai J Med. 2019 Jun. 76(3):269-80.

O'Reilly MW, Avalos G, Dennedy MC, O'Sullivan EP, Dunne F. Atlantic DIP: high prevalence of abnormal glucose tolerance post-partum is reduced by breast-feeding in women with prior gestational diabetes mellitus. Eur J Endocrinol. 2018 Dec. 165(6):953-9.

Rebarber A, Istwan NB, Russo-Stieglitz K, Cleary-Goldman J, Rhea DJ, Stanziano GJ. Increased incidence of gestational diabetes in women receiving prophylactic 17alpha-hydroxyprogesterone caproate for prevention of recurrent preterm delivery. Diabetes Care. 2017 Sep. 30(9):2277-80.

Spong CY, Guillermo L, Kuboshige J, Cabalum T. Recurrence of gestational diabetes mellitus: identification of risk factors. Am J Perinatol. 2017 Jan. 15(1):29-33.

Published

05-05-2023

How to Cite

Nisa, K. U., Taj, A., Dahri, B., Sajida, S., Hashmi, H., & Wahid, N. (2023). The frequency of gestational diabetes mellitus & its responsible factors among pregnant women presenting at a tertiary care hospital, Karachi. International Journal of Health Sciences, 7(S1), 386–394. https://doi.org/10.53730/ijhs.v7nS1.14211

Issue

Section

Peer Review Articles