Prevalence of esophageal eosinophilia in patients referred for diagnostic upper gastrointestinal endoscopy
Keywords:
esophageal eosinophilia, upper gastrointestinal endoscopy, GERDAbstract
Background and Aim: Esophageal eosinophilia such as gastro-esophageal reflux disease (GERD) and eosinophilic esophagitis (EoE) are associated with several conditions. Esophagus eosinophilic infiltration characterized the Eosinophilic esophagitis (EoE). The purpose of the present study was to determine the esophageal eosinophilia prevalence in patients underwent diagnostic upper gastrointestinal endoscopy. Patients and Methods: This cross-sectional study was carried out on 96 male adult patients underwent upper gastrointestinal endoscopy for unexplained upper GI symptoms in the department of Hepatology & Gastroenterology and Faculty of Medicine, DHQ Hospital Haripur KPK and Type-D Hospital Jamrud District Khyber from June 2022 to November 2022. Patient age>16 years with upper GI symptoms such as nausea, upper abdominal pain, dysphagia, vomiting, and heart burn referred for upper GI endoscopy were enrolled. Individual’s history, demographic details, physical examination, clinical details, laboratory tests such as serum creatinine, CBC, upper GI endoscopy, differential leucocytic count, liver biochemical tests, biopsy, and biopsy staining for histopathological examination were recorded. Data analysis was done in SPSS version 27. Results: Of the total 96 patients, incidence of Esophageal eosinophilia (EE), EoE, and low-grade esophageal eosinophilia was 33.3% (n=32), 5.2% (n=5), and 29.2% (n=28) respectively.
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Ahmed NA, Amer HA, Ibrahim DA, El-Zayyadi IA. Prevalence of esophageal eosinophilia in patients referred for diagnostic upper gastrointestinal endoscopy. Egyptian Liver Journal. 2021 Dec;11:1-7.
Walker MM, Potter M, Talley NJ (2018) Eosinophilic gastroenteritis and other eosinophilic gut diseases distal to the oesophagus. Lancet Gastroenterol Hepatol 3(4):271–280. https://doi.org/10.1016/S2468-1253(18)30005-0.
Dellon ES et al (2018) Updated international consensus diagnostic criteria for eosinophilic esophagitis: proceedings of the AGREE conference. Gastroenterology 155(4):1022–1033.e10.
Reed CC, Dellon ES (2019) Eosinophilic esophagitis. Med Clin North Am 103(1):29–42. https://doi.org/10.1016/j.mcna.2018.08.009.
Abe, Y.et al, Diagnosis and treatment of eosinophilic esophagitis in clinical practice. Clin J Gastroenterol, 2017. 10(2): p. 87-102, DOI: https://doi.org/10.1007/s12328-017-0725-4.
Mari A, Tsoukali E, Yaccob A (2020) Eosinophilic esophagitis in adults: a concise overview of an evolving disease. Korean J Fam Med 41(2):75–83.https://doi.org/10.4082/kjfm.18.0162.
Lucendo AJ, Arias Á (2017) The role of endoscopy in eosinophilic esophagitis: from diagnosis to therapy. 11(12):1135–1149.
Gomez-Aldana A et al (2019) Eosinophilic esophagitis: current concepts in diagnosis and treatment. World J Gastroenterol 25(32):4598–4613. https://doi.org/10.3748/wjg.v25.i32.4598.
Miehlke S et al (2020) Orodispersible budesonide tablets for the treatment of eosinophilic esophagitis: a review of the latest evidence. Ther Adv Gastroenterol 13:1756284820927282.
Gomez Torrijos E, Gonzalez-Mendiola R, Alvarado M, Avila R, Prieto-Garcia A, Valbuena T, Borja J, Infante S, Lopez MP, Marchan E, Prieto P, Moro M, Rosado A, Saiz V, Somoza ML, Uriel O, Vazquez A, Mur P, Poza-Guedes P, Bartra J (2018) Eosinophilic esophagitis: review and update. Front Med 5:247. https://doi.org/10.3389/fmed.2018.00247
Braunberger, R., Hanson, J. and Gonzalez, R. (2021) Eosinophilic esophagitis. Esophagus. Pathology outlines.com.
Eluri S, Dellon ES (2015) Proton pump inhibitor-responsive oesophageal eosinophilia and eosinophilic oesophagitis: more similarities than differences. Curr Opin Gastroenterol 31(4):309–315. https://doi.org/10.1097/MOG.0000000000000185.
Kellerman R, Kintanar T (2017) Gastroesophageal reflux disease. Prim Care 44(4):561–573. https://doi.org/10.1016/j.pop.2017.07.001.
Hunter S, Helmy D, Zayed N, El-Tayeb T, El-Serafy M (2014) Eosinophilic esophagitis in Egyptian adult patients presenting with upper gastrointestinal symptoms. Open J Gastroenterol 4(02):88–95. https://doi.org/10.4236/ojgas.2014.42015.
Wong S, Ruszkiewicz A, Holloway RH, Nguyen NQ (2018) Gastrooesophageal reflux disease and eosinophilic oesophagitis: what is the relationship? World J Gastrointest Pathophysiol 9(3):63–72. https://doi.org/10.4291/wjgp.v9.i3.63.
Arratibel P, Gil-Lasa I, Cobian J, Izagirre-Arostegi A, Arzallus T, Etxart A, Sarasqueta C, Zubiaurre L, Bujanda L. Incidence and evolution of foreign body impaction in the upper gastrointestinal tract and its relationship with eosionophilic oesophagitis. Gastroenterología y Hepatología. 2022 Apr 1;45(4):274-81.
Visaggi P, Ghisa M, Barberio B, Marabotto E, de Bortoli N, Savarino E. Systematic Review: esophageal motility patterns in patients with eosinophilic esophagitis. Digestive and Liver Disease. 2022 Jan 25.
Coşkun O, Çapraz M, Ahmet KA, Çetin Z. Detection and endoscopic treatment of foreign bodies in the upper gastrointestinal system of the geriatric patients. Journal of Contemporary Medicine. 2022;12(2):377-83.
HC Lin, CJ Chen, HH Lin, HH Lin, JT Huang, MJ Chen. Endoscopic Treatment of Esophageal Foreign Bodies in the Elderly. International Journal of Gerontology. 2013; 7:35-39
Yao CC, Wu IT, Lu LS, et al. Endoscopic management of foreign bodies in the upper gastrointestinal tract of adults. Biomed Res Int. 2015: 658602.
Birk M, Bauerfeind P, Deprez, et al. Removal of foreign bodies in the upper gastrointestinal tract in adults: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline. Endoscopy 2016; 48:489- 496.
de Souza Silva JE, Santos Souza CA, da Silva TB, et al. Use of herbal medicines by elderly patients: A systematic review. Arch Gerontol Geriatr. 2014;59(2):227-33
A. Schoepfer, et al. Eosinophilic esophagitis: latest insights from diagnosis to therapy Ann NY Acad Sci, 1434 (1) (2018), pp. 84-93.
G.D. Sciumé, et al. Eosinophilic esophagitis: novel concepts regarding pathogenesis and clinical manifestations Minerva Gastroenterol Dietol (2021).
Á. Arias, A.J. Lucendo Epidemiology and risk factors for eosinophilic esophagitis: lessons for clinicians Expert Rev Gastroenterol Hepatol, 14 (11) (2020), pp. 1069-1082.
M.V. Lenti, et al. Diagnostic delay and misdiagnosis in eosinophilic esophagitis Dig Liver Dis (2021).
I. Hirano, et al. Endoscopic assessment of the esophageal features of eosinophilic esophagitis: validation of a novel classification and grading system Gut, 62 (4) (2013), pp. 489-495.
Fouad M, Fouad YM, Mokareb HA, Mohamed EA, Abdel-Rehim DM (2018) Prevalence of eosinophilic esophagitis in adult patients with upper gastrointestinal symptoms in a locality in upper Egypt. Clin Endosc 51(4):357–361. https://doi.org/10.5946/ce.2017.166.
Sawada A, Hashimoto A, Uemura R et al (2019) Association between endoscopic findings of eosinophilic esophagitis and responsiveness to proton pump inhibitors. Endoscopy Int Open 7(4):E433.
Lee CY, Kao BZ, Wu CS, et al. Retrospective analysis of endoscopic management of foreign bodies in the upper gastrointestinal tract of adults.J Chin Med Assoc.2019; 82(2):105-109
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