Prevalence of asymptomatic bacteriuria and its antibacterial susceptibility pattern among pregnant women

https://doi.org/10.53730/ijhs.v7nS1.14329

Authors

  • Beenish Salam Gynaecologist and Obstetrician, King Abdullah Teaching Hospital, Mansehra Pakistan
  • Hawa Sardar Gynaecologist and Obstetrician, Obstetrics and Gynecology, TDH Khan Pur, Pakistan
  • Irum Shehzadi Gynaecologist and Obstetrician, King Abdullah Teaching Hospital, Mansehra Pakistan
  • Saba Ayub Gynaecologist and Obstetrician, RHC Havelian Pakistan

Keywords:

asymptomatic bacteriuria, antibacterial susceptibility, pregnant women

Abstract

Background and Aim: The condition of asymptomatic bacteriuria in pregnancy is common, and up to 40% of women developing pyelonephritis in pregnancy may suffer low birth weight and membrane’s premature rupture. The present study intended to investigate the incidence of asymptomatic bacteriuria and its antibacterial susceptibility pattern among pregnant women. Patients and Methods: This cross-sectional study was carried out on 183 pregnant women attending Obstetrics and Gynecology Department of Ayub Teaching Hospital, Abbottabad from December 2021 to May 2022. Pregnant women with asymptomatic bacteriuria attended the ANC services and willing to provide written consent were enrolled. Standard bacteriological procedures were followed for bacterial isolates identification using biochemical tests, colony characteristics, and Gram-staining. Kirby- Bauer disk diffusion technique was used for Antimicrobial susceptibility test on Muller-Hinton agar medium and Clinical Laboratory Standard Institute guidelines was used for interpretation of zone of inhibition diameter. Midstream urine samples were collected from each study participant and standard microbiological methods to culture urine, identify the pathogen, and conduct sensitivity tests. Data analysis was done in SPSS version 27. Results: The prevalence of asymptomatic bacteriuria was 14.2% (n=26) among pregnant women. 

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References

Ali G. M. Asymptomatic bacteriuria and antimicrobial susceptibility pattern of the isolates among pregnant women attending Dessie referral hospital, Northeast Ethiopia : a hospital-based cross-sectional study. Turk J Urol. 2018;44(3):251–60.

Jojan J. Davane. M, Patil CD, Nagoba B. asymptomatic bacteriuria in pregnant women from the rural area of Latur district of Maharashtra India. J Krishna Institute Med Sciences University. 2017;6(3):48–54.

Maternal SA. Neonatal & Gynaecology Community of practiceurologic. Clinics of North America. 2017:1–10.

Mokube MN, Atashili J, Halle-Ekane GE, Ikomey GM, Ndumbe PM (2013) Bacteriuria amongst Pregnant Women in the Buea Health District, Cameroon: Prevalence, Predictors, Antibiotic Susceptibility Patterns and Diagnosis. PLoS ONE 8(8): e71086. doi:10.1371/journal.pone.0071086

Bayati AH, Ghaib AH, Nasraldeen N, Hamalaw SA, Hamid ZA. Asymptomatic bacteriuria among pregnant women in sulaimani city. G.J.B.B. 2016;5(3):327–30.

Mwei MK. Asymptomatic bacteriuria among pregnant women attending antenatal clinic at Kilimanjaro Christian medical center in northern Tanzania. Clin Pract. 2018;15:917–22.

Mageto, Vincent Mogaka Gatwiri, Mathenge Scholastica Njoroge, wachukahospital r. Uropathogens antibiotic resistance patterns among type 2 diabetic patients in Kisii teaching and referral hospital, Kenya. Pan African Medical Journal 2018;8688:1–5.

Larsen B, Monif. Understanding the bacterial fora of the female genital tract. Clin Infect Dis. 2001;4198:69–77.

Abdul Kairun Nisha, Alemayehu Edossa Etana, and Hailemichael Tesso. prevalence of asymptomatic bacteriuria during pregnancy in Adama city, Ethiopia international journal of microbiology and immunology research. 2015;3(5), 058–063.

Adelaide,Ogutu A & Gideon K, Christine B, Samuel K. college prevalence etiology and antibiotic sensitivity profle of asymptomatic bacteriuria isolates from pregnant women in the selected antenatal clinic from Nairobi, Kenya the pan African medical journal. 2017;26:41.

Aliasghar Farazia, Mansooreh Jabbariasl B. an asymptomatic bacteriuria in pregnancy in the central region of Iran: frequency, risk factors, and causative organisms clinical epidemiology and global health, 2018;09; 009.

Kheya Mukherjee, Saroj Golia, Vasudha, Babita, Debojyoti Bhattacharjee, Goutam Chakraborty. a study on asymptomatic bacteriuria in pregnancy: prevalence, etiology, and comparison of screening methods Bengal, India international journal of research in medical sciences. 2014;(2)3:1087.

Ismail Ebrie Ali, Teklay Gebrecherkos, Mucheye Gizachew, Martha Alemayehu Menberu, asymptomatic bacteriuria and antimicrobial susceptibility pattern of the isolates among pregnant women attending Dessie referral hospital, Northeast Ethiopia: a hospital-based cross-sectional study, Turk j urol 2018; 44(3): 251–60.

Tadesse E, Teshome M, Merid Y, Kibret B, Shimelis T. Asymptomatic urinary tract infection among pregnant women attending the antenatal clinic of Hawass referral hospital, southern Ethiopia. BMC Res Notes. 2014;7:155.

Abu D, Abula T, Zewdu T, Berhanu M, Sahilu T. Asymptomatic Bacteriuria, antimicrobial susceptibility pattern and associated risk factors among pregnant women attending antenatal care in Assosa General Hospital, Western Ethiopia. BMC microbiology. 2021 Dec;21(1):1-8.

CLSI, editor. Performance standards for antimicrobial susceptibility testing. 27th ed. CLSI supplement M100. Clinical and Laboratory Standards Institute: Wayne, PA; 2017.

Hooton MT, Gupta K. Urinary tract infections and asymptomatic bacteriuria in pregnancy Accessed 16 Sep 2021. https://www.uptodate.com/contents/urinary-tract-infections-and-asymptomatic-bacteriuria-in-pregnancy.

Tadesse S, Kahsay T, Adhanom G, Kahsu G, Legese H, G/Wahid A, et al. Prevalence, antimicrobial susceptibility profle and predictors of asymptomatic bacteriuria among pregnant women in Adigrat General Hospital, Northern Ethiopia. BMC Res Notes. 2018;11(1):740.

Edae M, Teklemariam Z, Weldegebreal F, Abate D. Asymptomatic Bacteriuria among Pregnant Women Attending Antenatal Care at Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia. Magnitude, Associated Factors, and Antimicrobial Susceptibility Pattern. International Journal of Microbiology. 2020;2020:1763931.

Jyoti J, Milind Davane, Chandrakala Dawle,Basavraj Nagob. Asymptomatic bacteriuria in pregnant women from rural area of latur district of Maharashtra, India journal of Clinical and Diagnostic Research.2017; 6:3.

Elzayat MA, Barnett-Vanes A, Farag M, Dabour E, Cheng F. Prevalence of undiagnosed asymptomatic bacteriuria and associated risk factors during pregnancy : a cross-sectional study at two tertiary centers in Cairo, Egypt. BMJ. 2017:1–7.

Ali Hattem Bayati, Avan Hussain Ghaib, Narmeen Nasraldeen, Soran Amin Hamalaw & Zainab A. Hamid Asymptomatic bacteriuria among pregnant women in sulaimani city. g.j.b.b.2016: 5 (3)327–330.

Ujatha R, Nawan M. Prevalence of asymptomatic bacteriuria and its antibacterial susceptibility pattern among pregnant women attending he antenatal clinic at Kanpur, India. J Clin Diagn Res. 2014;8(4):01–3.

Tadesse S, Kahsay T, Adhanom G, Kahsu G, Legese H, Aderajew G. Prevalence, antimicrobial susceptibility profle and predictors of asymptomatic bacteriuria among pregnant women in Adigrat general hospital, northern Ethiopia. Bmc Res Notes. 2018:1–6.

Ali AH, Reda DY, Ormago MD. Prevalence and antimicrobial susceptibility pattern of urinary tract infection among pregnant women attending Hargeisa Group Hospital, Hargeisa, Somaliland. Scientific Reports. 2022 Jan 26;12(1):1419.

AlShamlan NA, AlOmar RS, Aldossary R, Alahmari M, Alghamdi A, AlGhamdi M, Alkanaan N, AlReedy AH, AlOtaibi AS, Alghamdi NS. The Epidemiology, Associated Factors and Bacterial Profile of Asymptomatic Bacteriuria in Pregnant Women: A Retrospective Chart Review Study in Saudi Arabia. International Journal of Women's Health. 2022 Dec 31:1749-59.

Bizuwork K, Alemayehu H, Medhin G, Amogne W, Eguale T. Asymptomatic bacteriuria among pregnant women in addis ababa, Ethiopia: prevalence, causal agents, and their antimicrobial susceptibility. Int J Microbiol. 2021;2021:8418043. doi:10.1155/2021/8418043.

Owens DK, Davidson KW, Krist AH, et al. Screening for Asymptomatic Bacteriuria in Adults: US Preventive Services Task Force Recommendation Statement. JAMA. 2019;322(12):1188–1194. doi:10.1001/jama.2019.13069.

Azami M, Jaafari Z, Masoumi M, et al. The etiology and prevalence of urinary tract infection and asymptomatic bacteriuria in pregnant women in Iran: a systematic review and Meta-analysis. BMC Urol. 2019;19(1):43. doi:10.1186/s12894-019-0454-8.

Lee AC, Mullany LC, Koffi AK, et al. Urinary tract infections in pregnancy in a rural population of Bangladesh: population-based prevalence, risk factors, etiology, and antibiotic resistance. BMC Pregnancy Childbirth. 2019;20(1):1. doi:10.1186/s12884-019-2665-0.

Nteziyaremye J, Iramiot SJ, Nekaka R, et al. Asymptomatic bacteriuria among pregnant women attending antenatal care at Mbale Hospital, Eastern Uganda. PLoS One. 2020;15(3):e0230523. doi:10.1371/journal.pone.0230523.

Puopolo KM, Lynfield R. Prevention of Group B Streptococcal Early-Onset Disease in Newborns: ACOG Committee Opinion Summary, Number 782. Obstet Gynecol. 2019;134(1):1.

Wabe YA, Reda DY, Abreham ET, Gobene DB, Ali MM. Prevalence of Asymptomatic Bacteriuria, Associated Factors and Antimicrobial Susceptibility Profile of Bacteria Among Pregnant Women Attending Saint Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia. Ther Clin Risk Manag. 2020;16:923–932. doi:10.2147/TCRM.S267101.

Abdel-Aziz Elzayat M, Barnett-Vanes A, Dabour MF, Cheng F. Prevalence of undiagnosed asymptomatic bacteriuria and associated risk factors during pregnancy: a cross-sectional study at two tertiary centres in Cairo, Egypt. BMJ open. 2017;7(3):e013198. doi:10.1136/bmjopen-2016-013198.

Rosenberger KD, Seibert A, Hormig S. Asymptomatic GBS bacteriuria during antenatal visits: to treat or not to treat? Nurse Pract. 2020;45(7):18–25. doi:10.1097/01.NPR.0000669112.69022.aa.

Published

07-06-2023

How to Cite

Salam, B., Sardar, H., Shehzadi, I., & Ayub, S. (2023). Prevalence of asymptomatic bacteriuria and its antibacterial susceptibility pattern among pregnant women. International Journal of Health Sciences, 7(S1), 1158–1165. https://doi.org/10.53730/ijhs.v7nS1.14329

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Section

Peer Review Articles