Clinical outcomes after maxillofacial reconstruction using the free fibular flap in children

A systematic review and meta-analysis

Authors

  • Ardeshir Khorsand Oral and Maxillofacial Surgery Resident, Department of Oral and Maxillofacial Surgery, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Rasool Saeedi Oral and maxillofacial surgery Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
  • Amirahmad Pahlavan Hoseini Department of Prosthodontics, Islamic Azad University of Medical Sciences, Dental School, Tehran, Iran
  • Mahnegar Shariati Department of Pediatrics, Islamic Azad University of Medical Sciences, Dental School, Tehran, Iran

Keywords:

maxillofacial, free fibular flap, children

Abstract

Background and aim: In the present study, an attempt has been made to investigate the complications and consequences of using the free fibular flap after maxillofacial reconstruction in children. Therefore, the present study was conducted with the aim of evaluating clinical outcomes after maxillofacial reconstruction using the free fibular flap in children. Method: Present study is a systematic review and meta-analysis based on PRISMA 2020 Checklist. Databases of PubMed, Scopus, Web of Science, EBSCO, ISI Web of Knowledge, and Embase were searched for systematic literature until 30 November 2022.  A 95% confidence interval for effect size with the random effect model and REML method were calculated. Meta-analysis was performed using Stata/MP v.17 software. Result: In the initial review, duplicate studies were eliminated and abstracts of 428 studies were reviewed, the full text of 155 studies was reviewed by two authors, and finally, 15 studies were selected. major and minor complication rate was 7% (ES, 7 95% CI 6%, 14%) and 23% (ES, 23% 95% CI 3%, 42%). Based on the present meta-analysis, the use of a free fibular flap is a reliable and appropriate option in reconstructing the jaw and face of children with few major complications and minor complications.

Downloads

Download data is not yet available.

References

Aston SJ, Beasley RW, Thorne CH. Grabb and Smith's plastic surgery: Lippincott-Raven; 1997.

Chung K. Grabb and Smith's plastic surgery: Lippincott Williams & Wilkins; 2019.

Warren SM, Borud LJ, Brecht LE, Longaker MT, Siebert JW. Microvascular reconstruction of the pediatric mandible. Plastic and reconstructive surgery. 2007;119(2):649-61.

Zhang W-B, Liang T, Peng X. Mandibular growth after paediatric mandibular reconstruction with the vascularized free fibula flap: a systematic review. International Journal of Oral and Maxillofacial Surgery. 2016;45(4):440-7.

Phillips JH, Rechner B, Tompson BD. Mandibular growth following reconstruction using a free fibula graft in the pediatric facial skeleton. Plastic and reconstructive surgery. 2005;116(2):419-24.

Maby A, Guay B, Thuot F. Infantile myofibromatosis treated by mandibulectomy and staged reconstruction with submental flap and free fibula flap: a case report. Journal of Otolaryngology-Head & Neck Surgery. 2019;48(1):1-10.

Crosby MA, Martin JW, Robb GL, Chang DW. Pediatric mandibular reconstruction using a vascularized fibula flap. Head & Neck: Journal for the Sciences and Specialties of the Head and Neck. 2008;30(3):311-9.

Fowler NM, Futran ND. Utilization of free tissue transfer for pediatric oromandibular reconstruction. Facial Plastic Surgery Clinics. 2014;22(4):549-57.

Faria JC, Batista BN, Sennes LU, Longo MV, Danila AH, Ferreira MC. Mandibular reconstruction with a fibular osteocutaneous free flap in an 8‐month‐old girl with a 12‐year follow‐up. Microsurgery. 2014;34(1):51-3.

Saleem M, Manohar MB, Hashim F. Compartment syndrome in a free fibula osteocutaneous flap donor site. British journal of plastic surgery. 1998;51(5):405-7.

Tugwell P, Tovey D. PRISMA 2020. Journal of Clinical Epidemiology. 2021;134:A5-A6.

Hassanein AG, Kukreja P, Hassanein KA, Mansour OM, Amer IA, Ftohy TE. Clinico-Pathological Characteristics, Management, and Outcome of Benign Intraosseous Maxillary Tumors in Adolescents: A Prospective Study. Journal of Craniofacial Surgery. 2022;33(6):e620-e6.

Hassanein AG, Kukreja P, Hassanein KAM, Mansour OM, Amer IA, Ftohy TE. Characteristics and Management of Pediatric Benign Intraosseous Mandibular Tumors: A 10-Years Prospective Study. Journal of Maxillofacial and Oral Surgery. 2022.

Fahradyan A, Odono L, Hammoudeh JA, Howell LK. Ameloblastic carcinoma in situ: review of literature and a case presentation in a pediatric patient. The Cleft Palate-Craniofacial Journal. 2019;56(1):94-100.

Ishida K. Successful reconstruction of agnathia by intraoral expansion and free vascularized fibula flap. Journal of Craniofacial Surgery. 2019;30(2):581-3.

Joseph ST, Thankappan K, Iyer S. Reconstruction of a combined maxillectomy and segmental mandibulectomy defect in a seven-year-old with a single free fibula osteocutaneous flap. Craniomaxillofacial Trauma & Reconstruction. 2017;10(1):73-6.

Cleveland EC, Zampell J, Avraham T, Lee Z-H, Hirsch D, Levine JP. Reconstruction of congenital mandibular hypoplasia with microvascular free fibula flaps in the pediatric population: a paradigm shift. Journal of Craniofacial Surgery. 2017;28(1):79-83.

Starnes-Roubaud MJ, Hanasono MM, Kupferman ME, Liu J, Chang EI. Microsurgical reconstruction following oncologic resection in pediatric patients: a 15-year experience. Annals of surgical oncology. 2017;24(13):4009-16.

Wong WW, Martin MC. Reconstruction of extended orbitomaxillectomy and hemimandibulectomy defects with fibula flaps and patient-specific implants. Journal of Craniofacial Surgery. 2016;27(2):380-4.

Han J, Hu L, Zhang C, Yang X, Tian Z, Wang Y, et al. Juvenile ossifying fibroma of the jaw: a retrospective study of 15 cases. International journal of oral and maxillofacial surgery. 2016;45(3):368-76.

Temiz G, Bilkay U, Tiftikçioğlu YÖ, Mezili CT, Songür E. The evaluation of flap growth and long‐term results of pediatric mandible reconstructions using free fibular flaps. Microsurgery. 2015;35(4):253-61.

Pierse J, Wun EY-P, Pellecchia R, Wollenberg J. Treatment of a rare ganglioneuroma with resection and reconstruction of the mandible: a case report and literature review. Journal of Oral and Maxillofacial Surgery. 2014;72(4):748. e1-. e9.

de la Parra M, Sanchez G, Lopez J, Perez A, Naal N. Total maxillary reconstruction using a double-barreled and double skin paddle fibular flap after total maxillectomy. Archives of Plastic Surgery. 2013;40(06):779-82.

Rashid M, Tamimy MS, Rizvi STA. Benign paediatric mandibular tumours: experience in reconstruction using vascularised fibula. Journal of Plastic, Reconstructive & Aesthetic Surgery. 2012;65(12):e325-e31.

Cho AM, Lopez J, Teven CM, Pourtaheri N, Do NT, Jazayeri HE, et al. Outcomes in Pediatric Maxillofacial Reconstruction With Vascularized Fibular Flaps: A Systematic Review. Journal of Craniofacial Surgery. 2022;33(5):1346-51.

Elledge R, Parmar S. Free flaps for head and neck cancer in paediatric and neonatal patients. Current Opinion in Otolaryngology & Head and Neck Surgery. 2018;26(2):127-33.

Cho AM, Lopez J, Teven CM, Pourtaheri N, Do NTK, Jazayeri HE, et al. Outcomes in Pediatric Maxillofacial Reconstruction With Vascularized Fibular Flaps: A Systematic Review. The Journal of craniofacial surgery. 2022;33(5):1346-51.

Published

08-06-2023

How to Cite

Khorsand, A., Saeedi, R., Hoseini, A. P., & Shariati, M. (2023). Clinical outcomes after maxillofacial reconstruction using the free fibular flap in children: A systematic review and meta-analysis. International Journal of Health Sciences, 7(S1), 1195–1203. Retrieved from https://sciencescholar.us/journal/index.php/ijhs/article/view/14334

Issue

Section

Peer Review Articles

Most read articles by the same author(s)