Clinical outcomes after maxillofacial reconstruction using the free fibular flap in children
A systematic review and meta-analysis
Keywords:
maxillofacial, free fibular flap, childrenAbstract
Background and aim: In the present study, an attempt has been made to investigate the complications and consequences of using the free fibular flap after maxillofacial reconstruction in children. Therefore, the present study was conducted with the aim of evaluating clinical outcomes after maxillofacial reconstruction using the free fibular flap in children. Method: Present study is a systematic review and meta-analysis based on PRISMA 2020 Checklist. Databases of PubMed, Scopus, Web of Science, EBSCO, ISI Web of Knowledge, and Embase were searched for systematic literature until 30 November 2022. A 95% confidence interval for effect size with the random effect model and REML method were calculated. Meta-analysis was performed using Stata/MP v.17 software. Result: In the initial review, duplicate studies were eliminated and abstracts of 428 studies were reviewed, the full text of 155 studies was reviewed by two authors, and finally, 15 studies were selected. major and minor complication rate was 7% (ES, 7 95% CI 6%, 14%) and 23% (ES, 23% 95% CI 3%, 42%). Based on the present meta-analysis, the use of a free fibular flap is a reliable and appropriate option in reconstructing the jaw and face of children with few major complications and minor complications.
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