Oral alterations among children with congenital zika virus syndrome

A systematic review and meta-analysis

Authors

  • Shahrzad Rezvani Doctor of Dental Surgery (DDS), Pedodontics, Tehran, Iran
  • Mohammad Niloufary Doctor of Dental Surgery (DDS), Hamedan University of Medical Sciences, School of Dental Medicine, Hamedan, Iran
  • Salar Motamedi Dental Research Center, Research Institute of Dental Sciences, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Neda Hajalizadeh Department of Pedodontics, Dental School Rafsanjan University of Medical Science, Rafsanjan, Iran

Keywords:

Children, Zika Virus, Congenital Zika Virus Syndrome, Oral Alterations, dental care

Abstract

Background and aim: the aim of present study was evaluating the oral alterations in children with congenital Zika syndrome -associated microcephaly compared to the group of children without this problem. Method: all international databases, PubMed, Scopus, Science Direct, ISI, and Embase were examined, searching between 2015 to March 2023 based on keywords related to the objectives of the study. Stata/MP v.17 software was used to conduct the meta-analysis. Result: After reviewing the abstracts of 177 articles, 21 articles were selected for full text review, of which 5 articles were included in the meta-analysis. Odds ratio of delayed tooth eruption between children with congenital Zika syndrome group and control group was 1.79 (OR, 1.79 95% CI 1.33, 2.25; p<0.001). Children with congenital Zika syndrome -associated microcephaly, compared to healthy children, had 2.15 (OR, 2.15 95% CI 1.62, 2.67; p<0.001) times chance of palate alteration. Conclusion: chance of delay in deciduous dental eruption, difficulty in lip sealing, palate alteration and ankyloglossia in children with CZS-associated microcephaly was significantly more than the control group.

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References

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Published

08-06-2023

How to Cite

Rezvani, S., Niloufary, M., Motamedi, S., & Hajalizadeh, N. (2023). Oral alterations among children with congenital zika virus syndrome: A systematic review and meta-analysis. International Journal of Health Sciences, 7(S1), 1227–1236. Retrieved from https://sciencescholar.us/journal/index.php/ijhs/article/view/14337

Issue

Section

Peer Review Articles