Implication of inflammatory markers in post COVID syndrome

https://doi.org/10.53730/ijhs.v7nS1.14558

Authors

  • Rohit Senior Resident Pathology
  • Manvi Sharma Senior Resident Medicine NC Medical College
  • Mayank Nangru Junior Resident Pathology
  • Ankit Gulia DM Cardiology Resident, DMC Ludhiana

Keywords:

post COVID, myalgia, D–dimer, C reactive protein (CRP)

Abstract

Post-COVID syndrome was described in the context of a survey of prolonged COVID-19 symptoms for the first time in 2020, run by the Patient-Led Research Collaborative, citizen’s scientist group. Symptoms persisting for more than three weeks after the diagnosis of COVID-19 fall into the category of post-COVID syndrome. The most common post-COVID symptoms include fatigue, dyspnea, olfactory and gustatory dysfunction, chest pain, myalgia, and sleep and mental disorders. The pathogenesis of post-COVID syndrome is multi-factorial. Underlying chronic, low grade inflammation has been theorized for pathogenesis. Available data shows conflicting results regarding the implication of inflammatory markers in full clinical spectrum and its long-term outcome.

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References

Patient-Led Research Collaborative. Report: What Does COVID-19 Recovery Actually Look Like? An Analysis of the Prolonged COVID-19 Symptoms Survey by Patient-Led Research Team. Available online: https://patientresearchcovid19.com/research/ report-1/ (accessed on 7 May 2021).

Writing Committee for the COMEBAC Study Group; Morin, L.; Savale, L.; Pham, T.; Colle, R.; Figueiredo, S.; Harrois, A.; Gasnier, M.; Lecoq, A.L.; Meyrignac, O.; et al. Four-month clinical status of cohort of patients after hospitalization for COVID-19. JAMA 2021. [CrossRef]

Alpert, O.; Begun, L.; Garren, P.; Solhkhah, R. Cytokine storm induced new onset depression in patients with COVID-19. A new look into the association between depression and cytokines—Two case reports. Brain Behav. Immun. Health 2020, 9, 100173. [CrossRef] [PubMed]

Dicpinigaitis, P.V.; Canning, B.J. Is there (will there be) a post-COVID-19 chronic cough? Lung 2020, 198, 863–865. [CrossRef]

Covid-19-Long-Term-Health-Effects. Available online: https://www.gov.uk/government/publications/covid-19-long-termhealth-effects/covid-19-long-term-health-effects (accessed on 7 May 2021).

Carvalho-Schneider, C.; Laurent, E.; Lemaignen, A.; Lemaignen, A.; Beaufils, E.; Bourbao-Tournois, C.; Laribi, S.; Flament, T.; Ferreira-Maldent, N.; Bruyère, F.; et al. Follow-up of adults with noncritical COVID-19 two months after symptom onset. Clin. Microbiol. Infect. 2021, 27, 258–263. [CrossRef] [PubMed]

Becker, R.C. COVID-19 and its sequelae: A platform for optimal patient care, discovery and training. J. Thromb. Thrombolysis 2021, 1–8. [CrossRef]

World Health Organization. Coronavirus Disease (COVID-19) Situation Reports. Available online: https://www.who.int/ emergencies/situation-reports

Ceban F, Ling S, Lui LMW, Lee Y, Gill H, Teopiz KM, Rodrigues NB, Subramaniapillai M, Di Vincenzo JD, Cao B, Lin K, Mansur RB, Ho RC, Rosenblat JD, Miskowiak KW, Vinberg M, Maletic V, McIntyre RS. Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis. Brain Behav Immun. 2022 Mar;101:93-135. doi: 10.1016/j.bbi.2021.12.020. Epub 2021 Dec 29. PMID: 34973396; PMCID: PMC8715665.

Kermali M, Khalsa RK, Pillai K, Ismail Z, Harky A. The role of biomarkers in diagnosis of COVID-19 - A systematic review. Life Sci. 2020 Aug 1;254:117788. doi: 10.1016/j.lfs.2020.117788. Epub 2020 May 13. PMID: 32475810; PMCID: PMC7219356.

Maamar M, Artime A, Pariente E, Fierro P, Ruiz Y, Gutiérrez S, Tobalina M, Díaz-Salazar S, Ramos C, Olmos JM, Hernández JL. Post-COVID-19 syndrome, low-grade inflammation and inflammatory markers: a cross-sectional study. Curr Med Res Opin. 2022 Jun;38(6):901-909. doi: 10.1080/03007995.2022.2042991. Epub 2022 Mar 9. PMID: 35166141; PMCID: PMC8935459.

Published

15-09-2023

How to Cite

Rohit, R., Sharma, M., Nangru, M., & Gulia, A. (2023). Implication of inflammatory markers in post COVID syndrome. International Journal of Health Sciences, 7(S1), 2644–2651. https://doi.org/10.53730/ijhs.v7nS1.14558

Issue

Section

Peer Review Articles