Ethnobotanical study of medicinal plants used in the prevention and treatment of COVID-19 infection in the Tiaret region (Algeria)

https://doi.org/10.53730/ijhs.v8n1.14658

Authors

  • Soudani Leila University Ibn Khaldoun, Tiaret, Algeria
  • Chafaa Meriem University Ibn Khaldoun, Tiaret, Algeria
  • Benabdelkrim Souad National Institute of Higher Paramedical Training of Tiaret, Algeria
  • Houcine Rekaia Local Public Health Etablishment of Tiaret, Algeria

Keywords:

Algeria, COVID-19, ethnobotanical survey, medicinal plants, Tiaret

Abstract

The Corona Virus disease has spread widely over the world with a high mortality rate. This spread has prompted people to look for other ways to treator minimize the negative impact of this out break. During the pandemic, the Algerian population used medicinal plants for the prevention and treatment of COVID-19. The present work was carried out to identify the medicinal plants used during COVID-19 by the population of Tiaret region (Algeria). An ethnobotanical survey was conducted to collect data on the medicinal plants used, including the socio demographic parameters of the users and floristic characteristics of the plants. Information was obtained from 428 participants, of which 67.05% were women, aged between 16 and 88 years old. Most plant users were between 41 and 64 years old. The majority of participants have a high level of education (55.14% university and 20.32% secondary). Quantitative indices, namely, Frequency of Citation (FC), Relative Frequency of Citation (RFC) and Family Importance Value (FIV) were used to analyze the data. 27 species of medicinal plants belonging to 15 botanical families used during the COVID - 19 pandemic in our region. The most used species were Syzygium aromaticum, Zingiber officinale, Citrus limon and Aloysia citriodora.

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References

Ahmad, M., Sultana, S., Fazl-i-Hadi, S., Ben Hadda, T., Rashid, S., Zafar, M., ... & Yaseen, G. (2014). An ethnobotanical study of medicinal plants in high mountainous region of Chail valley (District Swat-Pakistan). Journal of ethnobiology and ethnomedicine, 10, 1-18.

Akbulut, G., & Gencer-Bingol, F. (2021). Medical nutritional therapy for renal transplantation in the COVID-19 pandemic. World Journal of Transplantation, 11(6), 212.

AKBULUT, S. (2021). Medicinal plants preferences for the treatment of COVID-19 symptoms in Central and Eastern Anatolia. Kastamonu University Journal of Forestry Faculty, 21(3), 196-207.

Alalwan, T. A., Alkhuzai, J. A., Jameel, Z., & Mandeel, Q. A. (2019). Quantitative ethnobotanical study of some medicinal plants used by herbalists in Bahrain. Journal of Herbal Medicine, 17, 100278. https://doi.org/10.1016/j.hermed.2019.100278

Ali, B. H., Blunden, G., Tanira, M. O., & Nemmar, A. (2008). Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food and chemical Toxicology, 46(2), 409-420. https://doi.org/10.1016/j.fct.2007.09.085

Andrade, J. M., Faustino, C., Garcia, C., Ladeiras, D., Reis, C. P., & Rijo, P. (2018). Rosmarinus officinalis L.: an update review of its phytochemistry and biological activity. Future science OA, 4(4), FSO283.

Bahramsoltani, R., Rostamiasrabadi, P., Shahpiri, Z., Marques, A. M., Rahimi, R., & Farzaei, M. H. (2018). Aloysia citrodora Paláu (Lemon verbena): A review of phytochemistry and pharmacology. Journal of ethnopharmacology, 222, 34-51. https://doi.org/10.1016/j.jep.2018.04.021

Benkhaira, N., Koraichi, S. I., & Fikri-Benbrahim, K. (2021). Ethnobotanical survey on plants used by traditional healers to fight against COVID-19 in Fez city, Northern Morocco. Ethnobotany Research and Applications, 21, 1-18.

Benkhnigue, O., Zidane, L., Fadli, M., Elyacoubi, H., Rochdi, A., & Douira, A. (2010). Ethnobotanical study of medicinal plants in the Mechraâ Bel Ksiri region of Morocco. Acta Botanica Barcinonensia, (53), 191-216.

Boulware, D. R., Pullen, M. F., Bangdiwala, A. S., Pastick, K. A., Lofgren, S. M., Okafor, E. C., ... & Hullsiek, K. H. (2020). A randomized trial of hydroxychloroquine as postexposure prophylaxis for Covid-19. New England journal of medicine, 383(6), 517-525.

Boutabia, L., Telailia, S., & Menaa, M. (2020). Traditional therapeutic uses of Marrubium vulgare L. by local populations in the Haddada region (Souk Ahras, Algeria). Ethnobotany Research and Applications, 19, 1-11.

Bradai, L., Bouallala, M., Halassa, K., & Bouras, N. (2020). Diversity and use of medicinal plants cultivated in the South of Oued Righ. Afr. Rev. Sci. Tech. Dev , 5 (1), 61-70.

Brahmi, F., Iblhoulen, Y., Issaadi, H., Elsebai, M. F., Madani, K., & Boulekbache-Makhlouf, L. (2023). Ethnobotanical survey of medicinal plants of bejaia localities from algeria to prevent and treat coronavirus (COVID-19) infection shortened title: Phytomedicine to manage COVID-19 pandemic. Advances in Traditional Medicine, 23(3), 819-831.

Briguiche, H., & Zidane, L. (2019). Floristic and ethnobotanical study of medicinal plants used in the treatment of diseases of the respiratory system in the Doukkala region. Bulletin of the Scientific Institute, Rabat, Life Science Section , 41 , 33-41.

Chaachouay, N., Benkhnigue, O., Fadli, M., El Ibaoui, H., & Zidane, L. (2019). Ethnobotanical and ethnopharmacological studies of medicinal and aromatic plants used in the treatment of metabolic diseases in the Moroccan Rif. Heliyon, 5(10).

Chandorkar, N., Tambe, S., Amin, P., & Madankar, C. (2021). A systematic and comprehensive review on current understanding of the pharmacological actions, molecular mechanisms, and clinical implications of the genus Eucalyptus. Phytomedicine Plus, 1(4), 100089. https://doi.org/10.1016/j.phyplu.2021.100089

Chebaibi, M., Bousta, D., Bourhia, M., Baammi, S., Salamatullah, A. M., Nafidi, H. A., ... & Achour, S. (2022). Ethnobotanical study of medicinal plants used against COVID-19. Evidence-based Complementary and Alternative Medicine: eCAM, 2022.

Daoudi, A., Bammou, M., Zarkani, S., Slimani, I., Ibijbijen, J., & Nassiri, L. (2016). Ethnobotanical study of medicinal flora in rural municipality of Aguelmouss-Khenifra province–(Morocco). Phytothérapie, 14, 220-228.

Djahafi, A., Taïbi, K., & Abderrahim, L. A. (2021). Aromatic and medicinal plants used in traditional medicine in the region of Tiaret, North West of Algeria. Medit. Bot, 42, e71465.

Eddouks, M., Ajebli, M., & Hebi, M. (2017). Ethnopharmacological survey of medicinal plants used in Daraa-Tafilalet region (Province of Errachidia), Morocco. Journal of ethnopharmacology, 198, 516-530. https://doi.org/10.1016/j.jep.2016.12.017

EL ALAMI, A., Fattah, A., & Chait, A. (2020). Medicinal plants used for the prevention purposes during the covid-19 pandemic in Morocco. Journal of analytical sciences and applied biotechnology, 2(1), 2-1.

Ez zoubi, Y., Bousta, D., & Farah, A. (2020). A Phytopharmacological review of a Mediterranean plant: Lavandula stoechas L. Clinical Phytoscience, 6, 1-9.

Giday, M., Asfaw, Z., Elmqvist, T., & Woldu, Z. (2003). An ethnobotanical study of medicinal plants used by the Zay people in Ethiopia. Journal of ethnopharmacology, 85(1), 43-52. https://doi.org/10.1016/S0378-8741(02)00359-8

Hamdani, F.Z., & Houari, N. (2020). Phytotherapy and Covid-19. A study based on a survey in northern Algeria. Phytotherapy , 18 (5), 248-254.

Helali, A., Mokhtari, C., Ghoul, M., & Belhadef, MS (2020). Preventing infection by COVID19: what place for medicinal plants according to the Algerian population. Algerian journal of pharmacy , 3 (1), 2602-795X.

Hidayat, M., Muljono, P., Saleh, A., & Maarif, S. (2022). Communication strategy in the implementation of health belief model (HBM) at Bali Province in dealing with COVID-19. International Journal of Health Sciences, 6(S4), 5436-5449.

Hseini, S., & Kahouadji, A. (2007). Ethnobotanical study of medicinal flora in the Rabat region (western Morocco). Lazaroa , 28 , 79-93.

Ishtiaq, M., Maqbool, M., Ajaib, M., Ahmed, M., Hussain, I., Khanam, H., ... & Ghani, A. (2021). Ethnomedicinal and folklore inventory of wild plants used by rural communities of valley Samahni, District Bhimber Azad Jammu and Kashmir, Pakistan. Plos one, 16(1), e0243151.

Kabbaj, F., Meddah, B., Cherrah, Y., & Faouzi, E. (2012). Ethnopharmacological profile of traditional plants used in Morocco by cancer patients as herbal therapeutics. Phytopharmacology, 2(2), 243-256.

Kadri, Y., Moussaoui, A., & Benmebarek, A. (2019). Contribution to the floristic and ethnobotanical study of some medicinal plants used in certain regions of the Algerian Sahara" case of Timimoun, Adrar and Reggane". Analele Universitatii din Oradea, Fascicula Biologie, 26(2), 129-135.

Keni, R., Alexander, A., Nayak, P. G., Mudgal, J., & Nandakumar, K. (2020). COVID-19: emergence, spread, possible treatments, and global burden. Frontiers in public health, 216.

Khabbach, A., Libiad, M., Ennabili, A., & Bousta, D. (2012). Medicinal and cosmetic use of plants from the province of Taza, Northern Morocco. Boletin latinoamericano y del caribe de plantas medicinales y aromaticas, 11(1), 46-60.

Khadidja, H., & Sarah, M. (2021). Phytotherapy and natural products to the aid of conventional medicine in the treatment and prevention of COVID-19. Algerian Journal of Health Sciences , 79 .

Khadka, D., Dhamala, M. K., Li, F., Aryal, P. C., Magar, P. R., Bhatta, S., ... & Shi, S. (2021). The use of medicinal plants to prevent COVID-19 in Nepal. Journal of ethnobiology and ethnomedicine, 17(1), 1-17.

Klimek-Szczykutowicz, M., Szopa, A., & Ekiert, H. (2020). Citrus limon (Lemon) phenomenon—a review of the chemistry, pharmacological properties, applications in the modern pharmaceutical, food, and cosmetics industries, and biotechnological studies. Plants, 9(1), 119.

Kouame, KB, Anne, BJCPA, Yao, SS, Diane, KM, Diplo, TFB, Ouattara, A., ... & Dosso, M. (2021). Survey on the level of knowledge of medicinal plants used against Coronavirus disease, flu and colds among travelers who came for the COVID-19 test at the Pasteur Institute of Côte d'Ivoire. Journal of Applied Biosciences , 168 (1), 17456-17467.

Lawal, I. O., Olufade, I. I., Rafiu, B. O., & Aremu, A. O. (2020). Ethnobotanical survey of plants used for treating cough associated with respiratory conditions in Ede South local government area of Osun State, Nigeria. Plants, 9(5), 647.

Leila, S., Mhamed, M., Hermann, H., Mykola, K., Oliver, W., Christin, M., ... & Nadia, B. (2017). Fertilization value of municipal sewage sludge for Eucalyptus camaldulensis plants. Biotechnology reports, 13, 8-12. https://doi.org/10.1016/j.btre.2016.12.001

Lim, X. Y., Teh, B. P., & Tan, T. Y. C. (2021). Medicinal plants in COVID-19: potential and limitations. Frontiers in pharmacology, 12, 611408.

MAHAMMED, LL, MERAH, F., ALLAM, I., & DJIDJIK, R. (2019). Immunopathological mechanisms during SARS-CoV-2 infection. Algerian Journal of Allergology. Vol , 5 (01), 2543-3555.

Manzaba, F. D. M., & Rodríguez, M. A. Y. (2021). The technological revolution and its impact on current education: educational response to COVID-19. International Research Journal of Management, IT and Social Sciences, 8(1), 83-90.

Miara, MD, Hammou, MA, Hadjadj–Aoul, S., & Rebbas, K. (2014). Rediscovery of Otocarpus virgatus Durieu (Brassicaceae) in the Tiaret region (northwest of Algeria). Bull. Soc. linn. Provence , 65 , 31-31.

Mohammed, A., & Benchaben, H. (2016). Reflections on rainfall variations in the Tiaret region (Western Algeria) during the period: 1984-2015. European Scientific Journal , 12 (11).

Moore, H., Davies, M., Wanjohi, B. K., Njenga, E. W., Sudoi, V., & Kipkore, W. K. (2020). Ecological Knowledge of indigenous plants among the Marakwet Community (Embobut Basin), Elgeyo Marakwet County (Kenya). Ethnobotany Research and Applications: a journal of plants, people and applied research, 20.

Odebunmi, C. A., Adetunji, T. L., Adetunji, A. E., Olatunde, A., Oluwole, O. E., Adewale, I. A., ... & Aremu, T. O. (2022). Ethnobotanical survey of medicinal plants used in the treatment of COVID-19 and related respiratory infections in Ogbomosho South and North Local Government areas, Oyo State, Nigeria. Plants, 11(19), 2667.

Osmanlioğlu-Dağ, Ş., & UZ, A. (2018). Ginger’s place in pharmacy and antitumor effect Zencefilin Eczacılıktaki Yeri ve Antitümör Etkisi. Hacettepe University Journal of the Faculty of Pharmacy, 38(2).

Quezel, P., & Santa, S. (1963). Nouvelle flore de l'Algérie et des régions désertiques méridionales (No. 581.965 Q8).

Rathinavel, T., Palanisamy, M., Palanisamy, S., Subramanian, A., & Thangaswamy, S. (2020). Phytochemical 6-Gingerol–A promising Drug of choice for COVID-19. Int J Adv Sci Eng, 6(4), 1482-9.

Rosa, SGV, & Santos, WC (2020). Clinical trials of drug repositioning for the treatment of COVID-19. Pan American Journal of Public Health , 44 , NA-NA.

Salhi, S., Fadli, M., Zidane, L., & Douira, A. (2010). Floristic and ethnobotanical studies of medicinal plants in the city of Kenitra (Morocco). Mediterranean Botany , 31 , 133.

Salima, D., Radia, D., Nesrine, H., & Karima, M. (2022). Ethnobotanical study on the use of medicinal plants with antiviral interest, case of SARS-CoV-19, in the region of Seraidi (Annaba, north-east Algeria). Plant Archives, 22(2), 184-192.

Samouh, Y., Lemrani, A., Mimouni, H., Mohamad, J., & Said, A. A. H. (2019). Ethnopharmacological study of herbal medicines used to treat cancer in Morocco. The Journal of Phytopharmacology, 8(3), 135-141.

Sehailia, M., & Chemat, S. (2021). Antimalarial-agent artemisinin and derivatives portray more potent binding to Lys353 and Lys31-binding hotspots of SARS-CoV-2 spike protein than hydroxychloroquine: potential repurposing of artenimol for COVID-19. Journal of Biomolecular Structure and Dynamics, 39(16), 6184-6194.

Shukla, Y., & Singh, M. (2007). Cancer preventive properties of ginger: a brief review. Food and chemical toxicology, 45(5), 683-690. https://doi.org/10.1016/j.fct.2006.11.002

Slimani, I., Najem, M., Belaidi, R., Bachiri, L., Bouiamrine, EH, Nassiri, L., & Ibijbijen, J. (2016). Ethnobotanical Survey of medicinal plants used in Zerhoun region-Morocco-[Ethnobotanical Survey of medicinal plants used in Zerhoun region-Morocco-]. International Journal of Innovation and Applied Studies , 15 (4), 846.

Srivastava, V., Srivastava, S., Chaudhary, G., & Al-Turjman, F. (2020). A systematic approach for COVID-19 predictions and parameter estimation. Personal and Ubiquitous Computing, 1-13.

Sun, P., Lu, X., Xu, C., Sun, W., & Pan, B. (2020). Understanding of COVID‐19 based on current evidence. Journal of medical virology, 92(6), 548-551.

Suroowan, S., & Mahomoodally, M. F. (2016). A comparative ethnopharmacological analysis of traditional medicine used against respiratory tract diseases in Mauritius. Journal of Ethnopharmacology, 177, 61-80. https://doi.org/10.1016/j.jep.2015.11.029

Tahri, N., El BASTI, A., ZIDANE, L., ROCHDI, A., & DOUIRA, A. (2012). Ethnobotanical study of medicinal plants in the province of Settat (Morocco). Kastamonu University Journal of Forestry Faculty , 12 (2), 192-208.

Tardío, J., & Pardo-de-Santayana, M. (2008). Cultural importance indices: a comparative analysis based on the useful wild plants of Southern Cantabria (Northern Spain). Economic Botany, 62, 24-39.

Taylor, S., Landry, C. A., Paluszek, M. M., Fergus, T. A., McKay, D., & Asmundson, G. J. (2020). COVID stress syndrome: Concept, structure, and correlates. Depression and anxiety, 37(8), 706-714.

Thomford, N. E., Dzobo, K., Chopera, D., Wonkam, A., Skelton, M., Blackhurst, D., ... & Dandara, C. (2015). Pharmacogenomics implications of using herbal medicinal plants on African populations in health transition. Pharmaceuticals, 8(3), 637-663.

Trabut, L. (1935). Directory of native names of spontaneous plants, cultivated and used in North Africa . Print the “Typo-litho” and J. Carbonel combined.

Umeta Chali, B., Melaku, T., Berhanu, N., Mengistu, B., Milkessa, G., Mamo, G., ... & Mulugeta, T. (2021). Traditional medicine practice in the context of COVID-19 pandemic: Community claim in jimma zone, oromia, Ethiopia. Infection and Drug Resistance, 3773-3783.

Vitalini, S., Iriti, M., Puricelli, C., Ciuchi, D., Segale, A., & Fico, G. (2013). Traditional knowledge on medicinal and food plants used in Val San Giacomo (Sondrio, Italy)—An alpine ethnobotanical study. Journal of Ethnopharmacology, 145(2), 517-529. https://doi.org/10.1016/j.jep.2012.11.024

Vroh, BTA (2020). Diversity of plants used in traditional medicine against the main symptoms of COVID-19 in sub-Saharan Africa: literature review. Ethnobotany Research and Applications , 20 , 1-14.

Widoyo, H., Mohammed, Z. Y., Ramírez-Coronel, A. A., Iswanto, A. H., Thattarauthodiyil, U., S Alkhayyat, A., ... & Eftekhari, Z. (2022). Herbal therapy in Covid-19: A systematic review of medicinal plants effective against Covid-19. Caspian Journal of Environmental Sciences, 1-10.

Yang, F., Zhang, Y., Tariq, A., Jiang, X., Ahmed, Z., Zhihao, Z., ... & Bussmann, R. W. (2020). Food as medicine: A possible preventive measure against coronavirus disease (COVID‐19). Phytotherapy Research, 34(12), 3124-3136.

Yaseen, G., Ahmad, M., Sultana, S., Alharrasi, A. S., Hussain, J., & Zafar, M. (2015). Ethnobotany of medicinal plants in the Thar Desert (Sindh) of Pakistan. Journal of ethnopharmacology, 163, 43-59. https://doi.org/10.1016/j.jep.2014.12.053

Zemour, H., Sadoud, M., & Zoubeidi, M. (2020). Butchery practices in the region of Tiaret, Algeria: Case of sheep meat. Meats Prod , 36 , 1-9.

Zhukovets, T., & Özcan, M. M. (2020). A review: composition, use and bioactive properties of ginger (Zingiber officinale L.) rhizoms. J. Agroaliment. Proc. Technol, 26, 216.

Published

12-01-2024

How to Cite

Leila, S., Meriem, C., Souad, B., & Rekaia, H. (2024). Ethnobotanical study of medicinal plants used in the prevention and treatment of COVID-19 infection in the Tiaret region (Algeria). International Journal of Health Sciences, 8(1), 10–26. https://doi.org/10.53730/ijhs.v8n1.14658

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Peer Review Articles