Comparison of fluoroscopy guided inter-laminar epidural platelet-rich plasma versus steroid injection in patients with lumbar radicular pain

Abdullah Gaber Mohamed Abdelaziz; Tarek Mohamed Ahmed Sarhan; Ramdan Abd Elazim Ammar; Akram Abdel-Moneim Deghady; Hossam Kamel Saad Elrahmany

doi:10.53730/ijhs.v8nS1.14750

Authors

Abdullah Gaber Mohamed Abdelaziz
abdallagaber51@gmail.com
Assistant Lecturer of Anaesthesia and Surgical Intensive Care, Faculty of Medicine, Alexandria University, Egypt
Tarek Mohamed Ahmed Sarhan Professor of Anaesthesia and Surgical Intensive Care, Faculty of Medicine, Alexandria University, Egypt
Ramdan Abd Elazim Ammar Professor of Anaesthesia and Surgical Intensive Care, Faculty of Medicine, Alexandria University, Egypt
Akram Abdel-Moneim Deghady Professor of Clinical and Chemical Pathology, faculty of medicine, Alexandria university, Egypt
Hossam Kamel Saad Elrahmany Lecturer of Anaesthesia and Surgical Intensive Care, Faculty of Medicine, Alexandria University, Egypt

Keywords:

fluoroscopy, inter-laminar injection, platelet rich plasma, steroid, lumbar pain

Abstract

Background: Radicular back pain is one of the prevalent causes for low back pain. Objective: The aim of work is to compare the efficacies of fluoroscopic guided inter-laminar epidural injection of platelet-rich plasma (PRP) and epidural steroids in improving lumbar radicular pain. Settings and Design: This study was a prospective randomized controlled clinical trial. Methods: Forty-eight patients were enrolled in this study and divided into two groups. Steroid group (S); A 24 patient, that received fluoroscopic guided inter-laminar epidural injection of 1ml methylprednisolone (40mg/ml) + 4 ml normal saline and platelet rich Plasma group (p); A 24 patients, that received fluoroscopic guided inter-laminar epidural injection of 4.5 ml PRP + 0.5 ml PRP activator (calcium gluconate). Patients were followed up at one week, 4 weeks, and 3 months after the procedure. Results: No differences between study groups as regard pain scores at pretreatment, after 1 and 4 weeks and 3 months of treatment and disability scores at pretreatment, after 4 weeks and 3 months of treatment.

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