Relation between clinical status and right ventricular changes in corona virus disease 19 patients
Keywords:
COVID-19, RV dysfunction, CRP, D-dimerAbstract
Background: Role of laboratory parameters in prediction of COVID-19 severity and correlations with cardiac assessment is not well established and needs further investigations. This study was carried out to assess relation between clinical status and right ventricular changes in corona virus disease 19 patients using 2D echocardiography. Patients and methods: This cross sectional study was conducted on one hundred hospitalized COVID-19 PCR-positive patients with mild, moderate, or severe symptoms who were admitted to AL-MOKATTAM Health Insurance Hospital. Patients were subjected to detailed history taking, clinical examinations, laboratory investigations and transthoracic echocardiography. Results: In this study 100 Covid 19 patients (72 males and 28 females) with mean age of 63.13 ± 9.4 years (range: 33 – 86 years). The lab values are within normal ranges except oxygen saturation which was lower than normal values. The significant risk factors included hypertension, DM, smoking and dyslipidemia, the most prominent was dyslipidemia (50%), followed by smoking (33%), then hypertension (21%) and diabetes mellitus (15%). Relation of RV abnormality was associated with lymphocytes count, CKMB (creatinine kinase myocardial band), CRP, D-Dimer and ferritin (P: 0.005, P:0.001, P:0.000, P:0.017, P:0.015, respectively). Also, RV abnormality was associated with positive troponin (P<0.000).
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Võ PMT, Đinh CT, Nguyễn NTL, Lý ĐH, Trang VP, Phạm TKĐ, Hoàng TBN. 1. Coronavirus disease (COVID-19) – World Health Organization. Accessed March 3, 2023. https://www.who.int/emergencies/diseases/novel-coronavirus-2019 2. Mathieu E, Ritchie H, Rodés-Guirao L, et al. Coronavirus Pandemic (COVID-19). Our World in Data. Publ. Tạp chí Y học Việt Nam [Internet]. 2023;527(2).
Whittaker E, Bamford A, Kenny J, Kaforou M, Jones CE, Shah P, et al. Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2. JAMA [Internet]. 2020 Jul 21;324(3):259–69.
Belhadjer Z, Méot M, Bajolle F, Khraiche D, Legendre A, Abakka S, et al. Acute Heart Failure in Multisystem Inflammatory Syndrome in Children in the Context of Global SARS-CoV-2 Pandemic. Circulation [Internet]. 2020;142(5):429–36.
Leeb RT, Price S, Sliwa S, Kimball A, Szucs L, Caruso E, et al. COVID-19 Trends Among School-Aged Children - United States, March 1-September 19, 2020. MMWR Morb Mortal Wkly Rep [Internet]. 2020 Oct 2;69(39):1410–5.
Madjid M, Safavi-Naeini P, Solomon SD, Vardeny O. Potential effects of coronaviruses on the cardiovascular system: a review. JAMA Cardiol. 2020;5(7):831–40.
Keller M, Magunia H, Rosenberger P, Koeppen M. Echocardiography as a Tool to Assess Cardiac Function in Critical Care-A Review. Diagnostics (Basel, Switzerland). 2023 Feb;13(5).
Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, et al. Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr [Internet]. 2015;28(1):1-39.e14.
Kirkpatrick J, Mitchell C, Taub C, Kort S, Hung J, Swaminathan M. Ase Statement on Protection of Patients and Echocardiography Service Providers During the 2019 Novel Coronavirus Outbreak. J Indian Acad Echocardiogr & Cardiovasc Imaging [Internet]. 2020;4(1):137–43.
Bleakley C, Singh S, Garfield B, Morosin M, Surkova E, Mandalia MS, et al. Right ventricular dysfunction in critically ill COVID-19 ARDS. Int J Cardiol. 2021;327:251–8.
Peng F, Tu L, Yang Y, Hu P, Wang R, Hu Q, et al. Management and Treatment of COVID-19: The Chinese Experience. Can J Cardiol [Internet]. 2020/04/17. 2020 Jun;36(6):915–30.
Bangalore S, Sharma A, Slotwiner A, Yatskar L, Harari R, Shah B, et al. ST-Segment Elevation in Patients with Covid-19 - A Case Series. N Engl J Med [Internet]. 2020/04/17. 2020 Jun 18;382(25):2478–80.
Mahmoud-Elsayed HM, Moody WE, Bradlow WM, Khan-Kheil AM, Senior J, Hudsmith LE, Steeds RP. Echocardiographic Findings in Patients With COVID-19 Pneumonia. Can J Cardiol [Internet]. 2020/05/28. 2020 Aug;36(8):1203–7.
Kiss S, Gede N, Hegyi P, Németh D, Földi M, Dembrovszky F, et al. Early changes in laboratory parameters are predictors of mortality and ICU admission in patients with COVID-19: a systematic review and meta-analysis. Med Microbiol Immunol. 2021 Feb;210(1):33–47.
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