Frequency and risk factors associated with Low Birth Weight (LBW) at Bandung Regional General Hospital Indonesia

https://doi.org/10.53730/ijhs.v9n1.15503

Authors

  • Aghnia Purnama Putri Pediatric Intern, Bandung Regional General Hospital, Bandung, Indonesia
  • Ayu Alia Department of Pediatric, Bandung Regional General Hospital, Bandung, Indonesia
  • Junita Sinaga Department of Pediatric, Bandung Regional General Hospital, Bandung, Indonesia
  • Amelia Harsanti Department of Pediatric, Bandung Regional General Hospital, Bandung, Indonesia
  • Rissa Puspitari Sabur Department of Pediatric, Bandung Regional General Hospital, Bandung, Indonesia
  • Nada Kamilia Salsabila Pediatric Intern, Bandung Regional General Hospital, Bandung, Indonesia

Keywords:

IUGR, LBW, oligohydramnios, preeclampsia, PROM

Abstract

Low birth weight (LBW) was the highest contributor to the infant mortality rate at 52.4% in Bandung, Indonesia. The purpose of this study was to examine the incidence of LBW and associated risk factors. This study used a retrospective cross-sectional approach to identify 233 newborns with low birth weight from January to December 2022. The dependent (LBW) and independent variables (risk factors) were analyzed with a chi-square and Multivariate logistic regression test. The results in the bivariate analysis of this study were LBW was associated with preeclampsia (p = 0.001), gestational age (p = 0.000), premature rupture of the membranes (PROM) (p = 0.000), oligohydramnios (p = 0.019), multiple pregnancy (p = 0.000), and intrauterine growth restriction (IUGR) (p = 0.000). In multivariate analysis, LBW was associated with preeclampsia (p = 0.040 OR 1.806 CI 95% 1.028-3.173), gestational age (p = 0.000 OR 18.365 CI 95% 12.272-27.484), PROM (p = 0.007 OR 0.514 CI 95% 0.317-0.832), multiple pregnancy (p = 0.000 OR 4.934 CI 95% 2.246-10.841), and IUGR (p = 0.000 OR 0.043 CI 95% 0.018-0.107). Meanwhile, oligohydramnios was not associated with LBW (p = 0.099 OR 2.004 CI 95% 0.018-0.107).

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References

Albu, A. R., Anca, A. F., Horhoianu, V. V., & Horhoianu, I. A. (2014). Predictive factors for intrauterine growth restriction. Journal of medicine and life, 7(2), 165.

Alemu, A. A., & Aynalem, B. Y. (2022). Low birth weight in Ethiopia: A multilevel analysis of 2016 Ethiopian demographic and health survey. PAMJ-One Health, 9(5). DOI: https://doi.org/10.11604/pamj-oh.2022.9.5.31289

Anil, K.C., Basel, P. L., & Singh, S. (2020). Low birth weight and its associated risk factors: Health facility-based case-control study. PloS one, 15(6), e0234907. DOI: https://doi.org/10.1371/journal.pone.0234907

Armengaud, J. B., Yzydorczyk, C., Siddeek, B., Peyter, A. C., & Simeoni, U. (2021). Intrauterine growth restriction: Clinical consequences on health and disease at adulthood. Reproductive Toxicology, 99, 168-176. https://doi.org/10.1016/j.reprotox.2020.10.005 DOI: https://doi.org/10.1016/j.reprotox.2020.10.005

Conde-Agudelo, A., Villar, J., & Lindheimer, M. (2008). Maternal infection and risk of preeclampsia: systematic review and metaanalysis. American journal of obstetrics and gynecology, 198(1), 7-22. https://doi.org/10.1016/j.ajog.2007.07.040 DOI: https://doi.org/10.1016/j.ajog.2007.07.040

De Bernabé, J. V., Soriano, T., Albaladejo, R., Juarranz, M., Calle, M. E., Martı́nez, D., & Domı́nguez-Rojas, V. (2004). Risk factors for low birth weight: a review. European Journal of Obstetrics & Gynecology and Reproductive Biology, 116(1), 3-15. https://doi.org/10.1016/j.ejogrb.2004.03.007 DOI: https://doi.org/10.1016/j.ejogrb.2004.03.007

Desta, M. (2019). Low birth weight and adverse perinatal outcomes. In Childbirth (pp. 1-15). London: IntechOpen. DOI: https://doi.org/10.5772/intechopen.89049

Dinas Kesehatan Jawa Barat. (2019). Jumlah kematian neonatal berdasarkan penyebab kematian di Jawa Barat.

Faadhillah, A. (2020). Hubungan Preeklamsia dengan Kejadian BBLR di RSU Kabupaten Tangerang Tahun 2018. Jurnal Epidemiologi Kesehatan Indonesia, 4(1), 3. DOI: https://doi.org/10.7454/epidkes.v4i1.3199

Fatimah, N. I., Wahyuni, S., & Arifuddin, S. (2021). Procalcitonin levels differences in preeclampsia and non preeclampsia. International Journal of Health Sciences, 5(2), 71–78. https://doi.org/10.29332/ijhs.v5n3.1187 DOI: https://doi.org/10.29332/ijhs.v5n3.1187

Jung, E., Romero, R., Yeo, L., Gomez-Lopez, N., Chaemsaithong, P., Jaovisidha, A., ... & Erez, O. (2022). The etiology of preeclampsia. American journal of obstetrics and gynecology, 226(2), S844-S866. https://doi.org/10.1016/j.ajog.2021.11.1356 DOI: https://doi.org/10.1016/j.ajog.2021.11.1356

K’Oloo, A., Godfrey, E., Koivu, A. M., Barsosio, H. C., Manji, K., Ndesangia, V., ... & Näsänen-Gilmore, P. (2023). Improving birth weight measurement and recording practices in Kenya and Tanzania: a prospective intervention study with historical controls. Population health metrics, 21(1), 6. DOI: https://doi.org/10.1186/s12963-023-00305-x

Lake, E. A., & Olana Fite, R. (2019). Low birth weight and its associated factors among newborns delivered at wolaita sodo university teaching and referral hospital, southern Ethiopia, 2018. International journal of pediatrics, 2019(1), 4628301. DOI: https://doi.org/10.1155/2019/4628301

Lausman, A., McCarthy, F. P., Walker, M., & Kingdom, J. (2012). Screening, diagnosis, and management of intrauterine growth restriction. Journal of Obstetrics and Gynaecology Canada, 34(1), 17-28. https://doi.org/10.1016/S1701-2163(16)35129-5 DOI: https://doi.org/10.1016/S1701-2163(16)35129-5

Liu, Y., Li, N., An, H., Li, Z., Zhang, L., Li, H., ... & Ye, R. (2021). Impact of gestational hypertension and preeclampsia on low birthweight and small‐for‐gestational‐age infants in China: A large prospective cohort study. The Journal of Clinical Hypertension, 23(4), 835-842. DOI: https://doi.org/10.1111/jch.14176

Moradi, G., Zokaeii, M., Goodarzi, E., & Khazaei, Z. (2021). Maternal risk factors for low birth weight infants: A nested case-control study of rural areas in Kurdistan (western of Iran). Journal of preventive medicine and hygiene, 62(2), E399.

Nakimuli, A., Starling, J. E., Nakubulwa, S., Namagembe, I., Sekikubo, M., Nakabembe, E., ... & Aiken, C. E. (2020). Relative impact of pre-eclampsia on birth weight in a low resource setting: A prospective cohort study. Pregnancy hypertension, 21, 1-6. DOI: https://doi.org/10.1016/j.preghy.2020.04.002

Padayachee, L., Kale, M., Mannerfeldt, J., & Metcalfe, A. (2020). Oral misoprostol for induction of labour in Term PROM: a systematic review. Journal of Obstetrics and Gynaecology Canada, 42(12), 1525-1531. https://doi.org/10.1016/j.jogc.2020.02.111 DOI: https://doi.org/10.1016/j.jogc.2020.02.111

Pitt, C., Sanchez-Ramos, L., Kaunitz, A. M., & Gaudier, F. (2000). Prophylactic amnioinfusion for intrapartum oligohydramnios: a meta-analysis of randomized controlled trials. Obstetrics & Gynecology, 96(5), 861-866. https://doi.org/10.1016/S0029-7844(00)01054-1 DOI: https://doi.org/10.1016/S0029-7844(00)01054-1

Rabie, N., Magann, E., Steelman, S., & Ounpraseuth, S. (2017). Oligohydramnios in complicated and uncomplicated pregnancy: a systematic review and meta‐analysis. Ultrasound in Obstetrics & Gynecology, 49(4), 442-449. DOI: https://doi.org/10.1002/uog.15929

Romero, R., Kusanovic, J. P., Chaiworapongsa, T., & Hassan, S. S. (2011). Placental bed disorders in preterm labor, preterm PROM, spontaneous abortion and abruptio placentae. Best practice & research Clinical obstetrics & gynaecology, 25(3), 313-327. https://doi.org/10.1016/j.bpobgyn.2011.02.006 DOI: https://doi.org/10.1016/j.bpobgyn.2011.02.006

Shaohua, Y., Bin, Z., Mei, L., Jingfei, Z., Pingping, Q., Yanping, H., ... & Guoshun, M. (2022). Maternal risk factors and neonatal outcomes associated with low birth weight. Frontiers in genetics, 13, 1019321. DOI: https://doi.org/10.3389/fgene.2022.1019321

Sharma, D., Shastri, S., & Sharma, P. (2016). Intrauterine growth restriction: antenatal and postnatal aspects. Clinical medicine insights: pediatrics, 10, CMPed-S40070. DOI: https://doi.org/10.4137/CMPed.S40070

Sharma, S. R., Giri, S., Timalsina, U., Bhandari, S. S., Basyal, B., Wagle, K., & Shrestha, L. (2015). Low birth weight at term and its determinants in a tertiary hospital of Nepal: a case-control study. PloS one, 10(4), e0123962. DOI: https://doi.org/10.1371/journal.pone.0123962

Singh, G., Chouhan, R., & Sidhu, K. (2009). Maternal factors for low birth weight babies. Medical Journal Armed Forces India, 65(1), 10-12. https://doi.org/10.1016/S0377-1237(09)80045-2 DOI: https://doi.org/10.1016/S0377-1237(09)80045-2

Spinillo, A., Cesari, S., Bariselli, S., Tzialla, C., Gardella, B., & Silini, E. M. (2015). Placental lesions associated with oligohydramnios in fetal growth restricted (FGR) pregnancies. Placenta, 36(5), 538-544. https://doi.org/10.1016/j.placenta.2015.02.007 DOI: https://doi.org/10.1016/j.placenta.2015.02.007

Taneja, A., Arora, K., Chopra, I., & Naik, S. S. (2017). Pregnancy outcomes in isolated oligohydramnios during second trimester: a case series. Journal of Clinical and Diagnostic Research: JCDR, 11(8), QR01. DOI: https://doi.org/10.7860/JCDR/2017/27722.10502

Thapa, P., Poudyal, A., Poudel, R., Upadhyaya, D. P., Timalsina, A., Bhandari, R., ... & Adhikari, N. (2022). Prevalence of low birth weight and its associated factors: Hospital based cross sectional study in Nepal. PLOS Global Public Health, 2(11), e0001220. DOI: https://doi.org/10.1371/journal.pgph.0001220

Tshotetsi, L., Dzikiti, L., Hajison, P., & Feresu, S. (2019). Maternal factors contributing to low birth weight deliveries in Tshwane District, South Africa. PloS one, 14(3), e0213058. DOI: https://doi.org/10.1371/journal.pone.0213058

Wijaya, D., & Darusalam, D. (2022). The Impact of Premature Rupture of Membranes (PROM) and Low Birth Weight (LBW) Infant Outcomes to the Survival Rate. Indonesian Journal of Obstetrics and Gynecology, 72-78. DOI: https://doi.org/10.32771/inajog.v10i2.1553

World Health Organization. (2023). Low birth weight.

Zhang, S., Regnault, T. R., Barker, P. L., Botting, K. J., McMillen, I. C., McMillan, C. M., ... & Morrison, J. L. (2015). Placental adaptations in growth restriction. Nutrients, 7(1), 360-389. DOI: https://doi.org/10.3390/nu7010360

Zohdi, V., Sutherland, M. R., Lim, K., Gubhaju, L., Zimanyi, M. A., & Black, M. J. (2012). Low birth weight due to intrauterine growth restriction and/or preterm birth: Effects on nephron number and long‐term renal health. International journal of nephrology, 2012(1), 136942. DOI: https://doi.org/10.1155/2012/136942

Published

22-01-2025

How to Cite

Putri, A. P., Alia, A., Sinaga, J., Harsanti, A., Sabur, R. P., & Salsabila, N. K. (2025). Frequency and risk factors associated with Low Birth Weight (LBW) at Bandung Regional General Hospital Indonesia. International Journal of Health Sciences, 9(1), 124–132. https://doi.org/10.53730/ijhs.v9n1.15503

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Section

Peer Review Articles