Frequency and risk factors associated with Low Birth Weight (LBW) at Bandung Regional General Hospital Indonesia
Keywords:
IUGR, LBW, oligohydramnios, preeclampsia, PROMAbstract
Low birth weight (LBW) was the highest contributor to the infant mortality rate at 52.4% in Bandung, Indonesia. The purpose of this study was to examine the incidence of LBW and associated risk factors. This study used a retrospective cross-sectional approach to identify 233 newborns with low birth weight from January to December 2022. The dependent (LBW) and independent variables (risk factors) were analyzed with a chi-square and Multivariate logistic regression test. The results in the bivariate analysis of this study were LBW was associated with preeclampsia (p = 0.001), gestational age (p = 0.000), premature rupture of the membranes (PROM) (p = 0.000), oligohydramnios (p = 0.019), multiple pregnancy (p = 0.000), and intrauterine growth restriction (IUGR) (p = 0.000). In multivariate analysis, LBW was associated with preeclampsia (p = 0.040 OR 1.806 CI 95% 1.028-3.173), gestational age (p = 0.000 OR 18.365 CI 95% 12.272-27.484), PROM (p = 0.007 OR 0.514 CI 95% 0.317-0.832), multiple pregnancy (p = 0.000 OR 4.934 CI 95% 2.246-10.841), and IUGR (p = 0.000 OR 0.043 CI 95% 0.018-0.107). Meanwhile, oligohydramnios was not associated with LBW (p = 0.099 OR 2.004 CI 95% 0.018-0.107).
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References
Albu, A. R., Anca, A. F., Horhoianu, V. V., & Horhoianu, I. A. (2014). Predictive factors for intrauterine growth restriction. Journal of medicine and life, 7(2), 165.
Alemu, A. A., & Aynalem, B. Y. (2022). Low birth weight in Ethiopia: A multilevel analysis of 2016 Ethiopian demographic and health survey. PAMJ-One Health, 9(5). DOI: https://doi.org/10.11604/pamj-oh.2022.9.5.31289
Anil, K.C., Basel, P. L., & Singh, S. (2020). Low birth weight and its associated risk factors: Health facility-based case-control study. PloS one, 15(6), e0234907. DOI: https://doi.org/10.1371/journal.pone.0234907
Armengaud, J. B., Yzydorczyk, C., Siddeek, B., Peyter, A. C., & Simeoni, U. (2021). Intrauterine growth restriction: Clinical consequences on health and disease at adulthood. Reproductive Toxicology, 99, 168-176. https://doi.org/10.1016/j.reprotox.2020.10.005 DOI: https://doi.org/10.1016/j.reprotox.2020.10.005
Conde-Agudelo, A., Villar, J., & Lindheimer, M. (2008). Maternal infection and risk of preeclampsia: systematic review and metaanalysis. American journal of obstetrics and gynecology, 198(1), 7-22. https://doi.org/10.1016/j.ajog.2007.07.040 DOI: https://doi.org/10.1016/j.ajog.2007.07.040
De Bernabé, J. V., Soriano, T., Albaladejo, R., Juarranz, M., Calle, M. E., Martı́nez, D., & Domı́nguez-Rojas, V. (2004). Risk factors for low birth weight: a review. European Journal of Obstetrics & Gynecology and Reproductive Biology, 116(1), 3-15. https://doi.org/10.1016/j.ejogrb.2004.03.007 DOI: https://doi.org/10.1016/j.ejogrb.2004.03.007
Desta, M. (2019). Low birth weight and adverse perinatal outcomes. In Childbirth (pp. 1-15). London: IntechOpen. DOI: https://doi.org/10.5772/intechopen.89049
Dinas Kesehatan Jawa Barat. (2019). Jumlah kematian neonatal berdasarkan penyebab kematian di Jawa Barat.
Faadhillah, A. (2020). Hubungan Preeklamsia dengan Kejadian BBLR di RSU Kabupaten Tangerang Tahun 2018. Jurnal Epidemiologi Kesehatan Indonesia, 4(1), 3. DOI: https://doi.org/10.7454/epidkes.v4i1.3199
Fatimah, N. I., Wahyuni, S., & Arifuddin, S. (2021). Procalcitonin levels differences in preeclampsia and non preeclampsia. International Journal of Health Sciences, 5(2), 71–78. https://doi.org/10.29332/ijhs.v5n3.1187 DOI: https://doi.org/10.29332/ijhs.v5n3.1187
Jung, E., Romero, R., Yeo, L., Gomez-Lopez, N., Chaemsaithong, P., Jaovisidha, A., ... & Erez, O. (2022). The etiology of preeclampsia. American journal of obstetrics and gynecology, 226(2), S844-S866. https://doi.org/10.1016/j.ajog.2021.11.1356 DOI: https://doi.org/10.1016/j.ajog.2021.11.1356
K’Oloo, A., Godfrey, E., Koivu, A. M., Barsosio, H. C., Manji, K., Ndesangia, V., ... & Näsänen-Gilmore, P. (2023). Improving birth weight measurement and recording practices in Kenya and Tanzania: a prospective intervention study with historical controls. Population health metrics, 21(1), 6. DOI: https://doi.org/10.1186/s12963-023-00305-x
Lake, E. A., & Olana Fite, R. (2019). Low birth weight and its associated factors among newborns delivered at wolaita sodo university teaching and referral hospital, southern Ethiopia, 2018. International journal of pediatrics, 2019(1), 4628301. DOI: https://doi.org/10.1155/2019/4628301
Lausman, A., McCarthy, F. P., Walker, M., & Kingdom, J. (2012). Screening, diagnosis, and management of intrauterine growth restriction. Journal of Obstetrics and Gynaecology Canada, 34(1), 17-28. https://doi.org/10.1016/S1701-2163(16)35129-5 DOI: https://doi.org/10.1016/S1701-2163(16)35129-5
Liu, Y., Li, N., An, H., Li, Z., Zhang, L., Li, H., ... & Ye, R. (2021). Impact of gestational hypertension and preeclampsia on low birthweight and small‐for‐gestational‐age infants in China: A large prospective cohort study. The Journal of Clinical Hypertension, 23(4), 835-842. DOI: https://doi.org/10.1111/jch.14176
Moradi, G., Zokaeii, M., Goodarzi, E., & Khazaei, Z. (2021). Maternal risk factors for low birth weight infants: A nested case-control study of rural areas in Kurdistan (western of Iran). Journal of preventive medicine and hygiene, 62(2), E399.
Nakimuli, A., Starling, J. E., Nakubulwa, S., Namagembe, I., Sekikubo, M., Nakabembe, E., ... & Aiken, C. E. (2020). Relative impact of pre-eclampsia on birth weight in a low resource setting: A prospective cohort study. Pregnancy hypertension, 21, 1-6. DOI: https://doi.org/10.1016/j.preghy.2020.04.002
Padayachee, L., Kale, M., Mannerfeldt, J., & Metcalfe, A. (2020). Oral misoprostol for induction of labour in Term PROM: a systematic review. Journal of Obstetrics and Gynaecology Canada, 42(12), 1525-1531. https://doi.org/10.1016/j.jogc.2020.02.111 DOI: https://doi.org/10.1016/j.jogc.2020.02.111
Pitt, C., Sanchez-Ramos, L., Kaunitz, A. M., & Gaudier, F. (2000). Prophylactic amnioinfusion for intrapartum oligohydramnios: a meta-analysis of randomized controlled trials. Obstetrics & Gynecology, 96(5), 861-866. https://doi.org/10.1016/S0029-7844(00)01054-1 DOI: https://doi.org/10.1016/S0029-7844(00)01054-1
Rabie, N., Magann, E., Steelman, S., & Ounpraseuth, S. (2017). Oligohydramnios in complicated and uncomplicated pregnancy: a systematic review and meta‐analysis. Ultrasound in Obstetrics & Gynecology, 49(4), 442-449. DOI: https://doi.org/10.1002/uog.15929
Romero, R., Kusanovic, J. P., Chaiworapongsa, T., & Hassan, S. S. (2011). Placental bed disorders in preterm labor, preterm PROM, spontaneous abortion and abruptio placentae. Best practice & research Clinical obstetrics & gynaecology, 25(3), 313-327. https://doi.org/10.1016/j.bpobgyn.2011.02.006 DOI: https://doi.org/10.1016/j.bpobgyn.2011.02.006
Shaohua, Y., Bin, Z., Mei, L., Jingfei, Z., Pingping, Q., Yanping, H., ... & Guoshun, M. (2022). Maternal risk factors and neonatal outcomes associated with low birth weight. Frontiers in genetics, 13, 1019321. DOI: https://doi.org/10.3389/fgene.2022.1019321
Sharma, D., Shastri, S., & Sharma, P. (2016). Intrauterine growth restriction: antenatal and postnatal aspects. Clinical medicine insights: pediatrics, 10, CMPed-S40070. DOI: https://doi.org/10.4137/CMPed.S40070
Sharma, S. R., Giri, S., Timalsina, U., Bhandari, S. S., Basyal, B., Wagle, K., & Shrestha, L. (2015). Low birth weight at term and its determinants in a tertiary hospital of Nepal: a case-control study. PloS one, 10(4), e0123962. DOI: https://doi.org/10.1371/journal.pone.0123962
Singh, G., Chouhan, R., & Sidhu, K. (2009). Maternal factors for low birth weight babies. Medical Journal Armed Forces India, 65(1), 10-12. https://doi.org/10.1016/S0377-1237(09)80045-2 DOI: https://doi.org/10.1016/S0377-1237(09)80045-2
Spinillo, A., Cesari, S., Bariselli, S., Tzialla, C., Gardella, B., & Silini, E. M. (2015). Placental lesions associated with oligohydramnios in fetal growth restricted (FGR) pregnancies. Placenta, 36(5), 538-544. https://doi.org/10.1016/j.placenta.2015.02.007 DOI: https://doi.org/10.1016/j.placenta.2015.02.007
Taneja, A., Arora, K., Chopra, I., & Naik, S. S. (2017). Pregnancy outcomes in isolated oligohydramnios during second trimester: a case series. Journal of Clinical and Diagnostic Research: JCDR, 11(8), QR01. DOI: https://doi.org/10.7860/JCDR/2017/27722.10502
Thapa, P., Poudyal, A., Poudel, R., Upadhyaya, D. P., Timalsina, A., Bhandari, R., ... & Adhikari, N. (2022). Prevalence of low birth weight and its associated factors: Hospital based cross sectional study in Nepal. PLOS Global Public Health, 2(11), e0001220. DOI: https://doi.org/10.1371/journal.pgph.0001220
Tshotetsi, L., Dzikiti, L., Hajison, P., & Feresu, S. (2019). Maternal factors contributing to low birth weight deliveries in Tshwane District, South Africa. PloS one, 14(3), e0213058. DOI: https://doi.org/10.1371/journal.pone.0213058
Wijaya, D., & Darusalam, D. (2022). The Impact of Premature Rupture of Membranes (PROM) and Low Birth Weight (LBW) Infant Outcomes to the Survival Rate. Indonesian Journal of Obstetrics and Gynecology, 72-78. DOI: https://doi.org/10.32771/inajog.v10i2.1553
World Health Organization. (2023). Low birth weight.
Zhang, S., Regnault, T. R., Barker, P. L., Botting, K. J., McMillen, I. C., McMillan, C. M., ... & Morrison, J. L. (2015). Placental adaptations in growth restriction. Nutrients, 7(1), 360-389. DOI: https://doi.org/10.3390/nu7010360
Zohdi, V., Sutherland, M. R., Lim, K., Gubhaju, L., Zimanyi, M. A., & Black, M. J. (2012). Low birth weight due to intrauterine growth restriction and/or preterm birth: Effects on nephron number and long‐term renal health. International journal of nephrology, 2012(1), 136942. DOI: https://doi.org/10.1155/2012/136942
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