Outcomes following laparoscopic sleeve gastrectomy versus Roux-en-Y gastric bypass in morbidly obese patients: A comparative study
Keywords:
Bariatric surgery, Obesity, Weight loss, Laparoscopic Sleeve Gastrectomy, Laparoscopic Roux-en-Y gastric BypassAbstract
Background: Laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) are the two most common bariatric surgery methods performed worldwide. We aimed to contrast the LSG versus LRYGB effect in morbidly obese patients on obesity associated comorbidities and weight loss. Methods: This retrospective comparative research was performed through the period from 2019 to 2023 on 100 morbidly obese cases. Patients were designed into LSG group (50 patients underwent LSG) or LRYGB group (50 patients underwent LRYGB). Results: Excess weight loss (EWL) at one year follow up was insignificantly different between LSG and LRYGB groups while it was significantly improved in LRYGB group than LSG group at two years follow up (P value =0.027). The changes in hypertension, hypothyroidism, diabetes mellitus, obstructive sleep apnea syndrome, and gastro-oesophageal reflux disease (GERD) after surgery were insignificantly different between LRYGB and LSG groups. The number of oral hypoglycemic drugs, number of anti-hypertensive drugs, and thyroxine dosage after surgery were insignificantly different between LSG and LRYGB groups. Regarding postoperative complications, 3 (6%) cases progressd new-onset GERD in LSG group while 4 (8%) patients developed internal hernia, and 1 (2%) patient developed ulcer at gastrojejunal anastomosis in LRYGB group with insignificant difference between,,
Downloads
References
Arapis K, Macrina N, Kadouch D, Ribeiro Parenti L, Marmuse JP, Hansel B. Outcomes of Roux-en-Y gastric bypass versus sleeve gastrectomy in super-super-obese patients (BMI ≥60 kg/m2): 6-year follow-up at a single university. Surg Obes Relat Dis. 2019;15:23-33. DOI: https://doi.org/10.1016/j.soard.2018.09.487
Guraya SY, Strate T. Effectiveness of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy for morbid obesity in achieving weight loss outcomes. Int J Surg. 2019;70:35-43. DOI: https://doi.org/10.1016/j.ijsu.2019.08.010
Schauer PR, Ikramuddin S, Gourash W, Ramanathan R, Luketich J. Outcomes after laparoscopic Roux-en-Y gastric bypass for morbid obesity. Ann Surg. 2000;232:515-29. DOI: https://doi.org/10.1097/00000658-200010000-00007
Salminen P, Helmiö M, Ovaska J, Juuti A, Leivonen M, Peromaa-Haavisto P, et al. Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss at 5 Years Among Patients With Morbid Obesity: The SLEEVEPASS Randomized Clinical Trial. JAMA. 2018;319:241-54. DOI: https://doi.org/10.1001/jama.2017.20313
Biter LU, t Hart JW, Noordman BJ, Smulders JF, Nienhuijs S, Dunkelgrün M, et al. Long-term effect of sleeve gastrectomy vs Roux-en-Y gastric bypass in people living with severe obesity: a phase III multicentre randomised controlled trial (SleeveBypass). Lancet Reg Health Eur. 2024;38:1008-36. DOI: https://doi.org/10.1016/j.lanepe.2024.100836
Deitel M, Greenstein RJ. Recommendations for reporting weight loss. Obes Surg. 2003;13:159-60. DOI: https://doi.org/10.1381/096089203764467117
Reinhold RB. Critical analysis of long term weight loss following gastric bypass. Surg Gynecol Obstet. 1982;155:385-94.
Toghaw P, Matone A, Lenbury Y, De Gaetano A. Bariatric surgery and T2DM improvement mechanisms: a mathematical model. Theor Biol Med Model. 2012;9:1-15. DOI: https://doi.org/10.1186/1742-4682-9-16
Rubino F, Kaplan LM, Schauer PR, Cummings DE. The Diabetes Surgery Summit consensus conference: recommendations for the evaluation and use of gastrointestinal surgery to treat type 2 diabetes mellitus. Ann Surg. 2010;251:399-405. DOI: https://doi.org/10.1097/SLA.0b013e3181be34e7
Peterli R, Wölnerhanssen BK, Peters T, Vetter D, Kröll D, Borbély Y, et al. Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss in patients with morbid obesity: the SM-BOSS randomized clinical trial. Jama. 2018;319:255-5. DOI: https://doi.org/10.1001/jama.2017.20897
Helmiö M, Victorzon M, Ovaska J, Leivonen M, Juuti A, Jaser N, et al. SLEEVEPASS: a randomized prospective multicenter study comparing laparoscopic sleeve gastrectomy and gastric bypass in the treatment of morbid obesity: preliminary results. Surg Endosc. 2012;26:2521-26. DOI: https://doi.org/10.1007/s00464-012-2225-4
Baheeg M, El-Din MT, Labib MF, Elgohary SA, Hasan A. Long-term durability of weight loss after bariatric surgery; a retrospective study. Int J Surg Open. 2021;28:37-40. DOI: https://doi.org/10.1016/j.ijso.2020.12.008
Sherif TM. Prospective comparative study between laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy in the management of morbid obesity and its comorbidities. Egypt J Surg. 2016;35:83-8. DOI: https://doi.org/10.4103/1110-1121.182769
Wölnerhanssen BK, Peterli R, Hurme S, Bueter M, Helmiö M, Juuti A, et al. Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy: 5-year outcomes of merged data from two randomized clinical trials (SLEEVEPASS and SM-BOSS). Br J Surg. 2021;108:49-57. DOI: https://doi.org/10.1093/bjs/znaa011
Yang J, Wang C, Cao G, Yang W, Yu S, Zhai H, et al. Long-term effects of laparoscopic sleeve gastrectomy versus roux-en-Y gastric bypass for the treatment of Chinese type 2 diabetes mellitus patients with body mass index 28-35 kg/m 2. BMC surgery. 2015;15:1-7. DOI: https://doi.org/10.1186/s12893-015-0074-5
Yang P, Chen B, Xiang S, Lin X-F, Luo F, Li W. Long-term outcomes of laparoscopic sleeve gastrectomy versus Roux-en-Y gastric bypass for morbid obesity: results from a meta-analysis of randomized controlled trials. Surg Obes Relat Dis. 2019;15:546-55. DOI: https://doi.org/10.1016/j.soard.2019.02.001
Golzarand M, Toolabi K, Farid R. The bariatric surgery and weight losing: a meta-analysis in the long-and very long-term effects of laparoscopic adjustable gastric banding, laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy on weight loss in adults. Surg Endosc. 2017;31:4331-45. DOI: https://doi.org/10.1007/s00464-017-5505-1
Kowalewski PK, Olszewski R, Walędziak MS, Janik MR, Kwiatkowski A, Gałązka-Świderek N, et al. Long-term outcomes of laparoscopic sleeve gastrectomy—a single-center, retrospective study. Obesity surgery. 2018;28:130-4. DOI: https://doi.org/10.1007/s11695-017-2795-2
Grönroos S, Helmiö M, Juuti A, Tiusanen R, Hurme S, Löyttyniemi E, et al. Effect of laparoscopic sleeve gastrectomy vs Roux-en-Y gastric bypass on weight loss and quality of life at 7 years in patients with morbid obesity: the SLEEVEPASS randomized clinical trial. JAMA Surg. 2021;156:137-46. DOI: https://doi.org/10.1001/jamasurg.2020.5666
Sjöström L, Lindroos A-K, Peltonen M, Torgerson J, Bouchard C, Carlsson B, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med 2004;351:2683-93. DOI: https://doi.org/10.1056/NEJMoa035622
Musella M, Apers J, Rheinwalt K, Ribeiro R, Manno E, Greco F, et al. Efficacy of bariatric surgery in type 2 diabetes mellitus remission: the role of mini gastric bypass/one anastomosis gastric bypass and sleeve gastrectomy at 1 year of follow-up. A European survey. Obes Surg. 2016;26:933-40. DOI: https://doi.org/10.1007/s11695-015-1865-6
Celio AC, Wu Q, Kasten KR, Manwaring ML, Pories WJ, Spaniolas K. Comparative effectiveness of Roux-en-Y gastric bypass and sleeve gastrectomy in super obese patients. Surg Endosc. 2017;31:317-23. DOI: https://doi.org/10.1007/s00464-016-4974-y
Maggard-Gibbons M, Maglione M, Livhits M, Ewing B, Maher AR, Hu J, et al. Bariatric surgery for weight loss and glycemic control in nonmorbidly obese adults with diabetes: a systematic review. Jama. 2013;309:2250-61. DOI: https://doi.org/10.1001/jama.2013.4851
Baheeg M, Elgohary SA, Tag-Eldin M, Hegab AM, Shehata MS, Osman EM, et al. Effect of laparoscopic sleeve gastrectomy vs laparoscopic Roux-en-Y gastric bypass on weight loss in Egyptian patients with morbid obesity. Ann Med Surg. 2022;73:103-235. DOI: https://doi.org/10.1016/j.amsu.2021.103235
Zhang Y, Zhao H, Cao Z, Sun X, Zhang C, Cai W, et al. A randomized clinical trial of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy for the treatment of morbid obesity in China: a 5-year outcome. Obes Surg. 2014;24:1617-24. DOI: https://doi.org/10.1007/s11695-014-1258-2
Lakdawala MA, Bhasker A, Mulchandani D, Goel S, Jain S. Comparison between the results of laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass in the Indian population: a retrospective 1 year study. Obes Surg. 2010;20:1-6. DOI: https://doi.org/10.1007/s11695-009-9981-9
Garg H, Priyadarshini P, Aggarwal S, Agarwal S, Chaudhary R. Comparative study of outcomes following laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy in morbidly obese patients: a case control study. World J Gastrointest Endosc. 2017;9:1-62. DOI: https://doi.org/10.4253/wjge.v9.i4.162
El Chaar M, Hammoud N, Ezeji G, Claros L, Miletics M, Stoltzfus J. Laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass: a single center experience with 2 years follow-up. Obes Surg. 2015;25:254-62. DOI: https://doi.org/10.1007/s11695-014-1388-6
Boza C, Gamboa C, Salinas J, Achurra P, Vega A, Pérez G. Laparoscopic Roux-en-Y gastric bypass versus laparoscopic sleeve gastrectomy: a case-control study and 3 years of follow-up. Surg Obes Relat Dis. 2012;8:243-9. DOI: https://doi.org/10.1016/j.soard.2011.08.023
Li J-F, Lai D-D, Ni B, Sun K-X. Comparison of laparoscopic Roux-en-Y gastric bypass with laparoscopic sleeve gastrectomy for morbid obesity or type 2 diabetes mellitus: a meta-analysis of randomized controlled trials. Can J Surg. 2013;56:1-58. DOI: https://doi.org/10.1503/cjs.026912
Published
How to Cite
Issue
Section
Copyright (c) 2025 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
