Effect of two different dose regimens of magnesium sulphate on postoperative pain relief after elective inguinal hernioplasty: A randomized controlled study
Keywords:
Magnesium, Analgesia, Pain Relief, Inguinal Hernia RepairAbstract
Background: Postoperative pain following hernia repair is most severe the day following surgeries, with two-thirds experiencing moderate to severe pain throughout activity, and one-third still reporting pain after one week. About 10% continue to have pain after 4 weeks. The aim of this work was to contrast the impact of two dose regimens of magnesium on post-operative pain relief in inguinal hernia surgery. Methods: This prospective randomized-blinded work involved 60 individuals (21-50 years old) scheduled for hernioplasty under general anesthesia. Participants had been allocated into three groups: Group A received a magnesium sulfate (MgSO4) bolus (40 mg/kg) and infusion (10 mg/kg/hour) before skin incision; Group B received a MgSO4bolus (40 mg / kg) diluted in 50 ml normal saline 10 mins before induction followed by equal volume of normal saline infusion started before skin incision, Group C received normal saline bolus and infusion before skin incision. Results: The time of first and total dose of nalbuphine and total amount of atracurium revealed a substantial reduction in group A and the other two groups.
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