Frequency of in hospital mortality of cirrhotic patients due to sepsis

Sidra Dars; Osama Ahmed; Ubedullah Bughio; Muhammad Asif; Muhammad Sadik Memon; Saadat Ali Jiskani

doi:10.53730/ijhs.v9nS1.15692

Authors

Sidra Dars Consultant Gastroenterologist Asian Institute Of Medical Science Hyderabad
Osama Ahmed Consultant Gastroenterologist Dr Zeenat Issani Institute of Medical Science Shikarpur
Ubedullah Bughio
drbughio@gmail.com
Senior Registrar Gastroenterology Asian Institute of Medical Science Hyderabad
Muhammad Asif Assistant Proffesor Gastroenterology Kohat Medical College
Muhammad Sadik Memon Proffesor Asian Institute of Medical Science Hyderabad
Saadat Ali Jiskani Assistant Professor Gastroenterology Asian Institute Of Medical Science Hyderabad

Keywords:

Mortality, Cirrhotic, Sepsis, MELD, Survival, Infection, Child-Pugh Score

Abstract

Introduction: Infection is a common complication of liver cirrhosis, as 30–50% of patients with cirrhosis either present with infection during admission, or develop infection during hospitalization. The severity of the underlying liver disease makes patients with cirrhosis more susceptible to the development of sepsis, compared to the general population. Patients with cirrhosis have a high risk of developing sepsis. According to the Global Burden of Disease study, liver cirrhosis caused 1.2% of global disability adjusted life years and 2% of all deaths worldwide in 2010. Objective: To determine the frequency of in hospital mortality of cirrhotic patients due to sepsis. Materials and Methods: It is Descriptive Study conducted at Department of Gastroenterology, Asian Institute of Medical Science (AIMS), Hyderabad, Pakistan from January 31, 2020 to July 30, 2020. All patients who fulfilled the inclusion criteria and visited to AIMS; Hyderabad were included in the study. Child-Turcotte-Pugh (CTP) score was calculated by clinical parameters, i.e. encephalopathy and ascites, and laboratory results, i.e. bilirubin and albumin concentrations, and prothrombin time and MELD score were calculated by it using laboratory parameters bilirubin, serum creatinine and international normalization ratio (INR).

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