Functional impairment and disability in euthymic Libyan adults with bipolar disorder: A cross-sectional study
Keywords:
bipolar disorder, cross-sectional study, disability, euthymia, functional impairment, LibyaAbstract
Background: Bipolar disorder is a primary contributor to global disability. A critical gap exists between symptomatic remission and functional recovery, with many patients experiencing persistent impairment even during euthymia. However, empirical data from North African populations, particularly Libya, remain scarce. This study aimed to quantify the extent of this issue in a Libyan clinical sample. Objective: To assess the prevalence and severity of functional impairment and disability in euthymic Libyan patients with BPD and to identify associated socio-demographic and clinical correlates. Methods: In this cross-sectional study, 100 outpatients with a DSM-5 diagnosis of BPD were recruited from three psychiatric clinics in Libya. Euthymia was confirmed using cutoff scores of ≤7 on the Hamilton Depression Rating Scale and ≤6 on the Young Mania Rating Scale. Functional impairment was evaluated using the Functioning Assessment Short Test, and disability was measured with the World Health Organization Disability Assessment Schedule. Associations were analysed using Chi-square tests, with significance set at p < 0.05. Results: The sample comprised 100 participants (97% with Bipolar I Disorder). Despite being in remission, only 44.0% exhibited normal functioning, while 35.0% had mild, 18.0% moderate, and 3.0% severe functional impairment.
Downloads
References
Chaudhury, P. K., Deka, K., & Chetia, D. (2006). Disability associated with mental disorders. Indian journal of psychiatry, 48(2), 95-101.
Fountoulakis, K. N., Vieta, E., Sanchez-Moreno, J., Kaprinis, S. G., Goikolea, J. M., & Kaprinis, G. S. (2005). Treatment guidelines for bipolar disorder: a critical review. Journal of affective disorders, 86(1), 1-10. https://doi.org/10.1016/j.jad.2005.01.004
Grande, I., Berk, M., Birmaher, B., & Vieta, E. (2016). Bipolar disorder. The Lancet, 387(10027), 1561-1572.
Judd, L. L., Akiskal, H. S., Schettler, P. J., Endicott, J., Leon, A. C., Solomon, D. A., ... & Keller, M. B. (2005). Psychosocial disability in the course of bipolar I and II disorders: a prospective, comparative, longitudinal study. Archives of general psychiatry, 62(12), 1322-1330.
Judd, L. L., Akiskal, H. S., Schettler, P. J., Endicott, J., Maser, J., Solomon, D. A., ... & Keller, M. B. (2002). The long-term natural history of the weekly symptomatic status of bipolar I disorder. Archives of general psychiatry, 59(6), 530-537.
Khan, A. A., Chouhan, P., & Qureshi, R. (2016). A comparative study of disability and its burden on family members of bipolar and unipolar depression patients. Education, 9, 30-0.
McDermott, S., & Turk, M. A. (2011). The myth and reality of disability prevalence: measuring disability for research and service. Disability and Health Journal, 4(1), 1-5. https://doi.org/10.1016/j.dhjo.2010.06.002
Murray, C. J., & Lopez, A. D. (1997). Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. The lancet, 349(9063), 1436-1442.
Rehabilitation Committee of the Indian Psychiatry Society. (2002). IDEAS (Indian Disability Evaluation and Assessment Scale). Kolkata: IPS.
Rosa, A. R., Sánchez-Moreno, J., Martínez-Aran, A., Salamero, M., Torrent, C., Reinares, M., ... & Vieta, E. (2007). Validity and reliability of the Functioning Assessment Short Test (FAST) in bipolar disorder. Clinical Practice and Epidemiology in Mental Health, 3(1), 5.
Sanderson, K., & Andrews, G. (2002). Prevalence and severity of mental health-related disability and relationship to diagnosis. Psychiatric services, 53(1), 80-86.
Szmulewicz, A. G., Valerio, M. P., Smith, J. M., Samamé, C., Martino, D. J., & Strejilevich, S. A. (2017). Neuropsychological profiles of major depressive disorder and bipolar disorder during euthymia. A systematic literature review of comparative studies. Psychiatry research, 248, 127-133. https://doi.org/10.1016/j.psychres.2016.12.031
Weissman, M. M., Bland, R. C., Canino, G. J., Faravelli, C., Greenwald, S., Hwu, H. G., ... & Yeh, E. K. (1996). Cross-national epidemiology of major depression and bipolar disorder. Jama, 276(4), 293-299.
Published
How to Cite
Issue
Section
Copyright (c) 2025 International journal of health sciences

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.