Evaluation of the diagnostic value of DWI with multiple synthetic b-values of breast lesions compared to dynamic contrast-enhanced breast MRI
Keywords:
DWI, Synthetic b-values, Breast CancerAbstract
Background: Several studies have demonstrated that the sensitivity of unenhanced MRI with DWI was equal or superior to mammography; however, there is still room for improvement. Diffusion sensitivity, better known as “b- value,” has important implications for tumor conspicuity and can be controlled by modifying the magnitude and duration of the diffusion gradients. Aim: The aim of our study was to assess lesion visibility and the diagnostic performance of DWI for breast cancer detection by the addition of different synthetic b-values. Patients and Methods: this prospective study is IRB approved. Patients presented for both screening and diagnostic purpose were included. All patients underwent breast MRI with DWI with addition of different synthetic b-values. Three readers evaluated DWI with acquired synthetic b-800, b-1000, b-1200, b-1500, and b-1800 s/mm2 images. The readers determined the preferred b-value based on lesion visibility and conspicuity. Results: One hundred and fourteen patients met our study criteria. One hundred twenty-five breast lesions in 114 women were detected. The mean age of our population is (39.6 ± 5.9 years old) ranged from 30 to 50 years old. Lesion size ranged from 5 to 100 mm with mean size of (25.9 ± 16.9 mm).
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