The influence of granting ngor eggplant (solanium indicum) extract inhibiting of spermatogenesis in mice (mus musculus)

https://doi.org/10.21744/ijhs.v1i2.35

Authors

  • Nyoman Suarjana Public Health Study Program, Dhyana Pura University
  • I Nyoman Mangku Karmaya Faculty of Medic and Health Science, Udayana University
  • Bagus Komang Satriyasa Faculty of Medic and Health Science, Udayana University
  • J. Alex Pangkahila Faculty of Medic and Health Science, Udayana University
  • Ni Putu Widya Astuti Public Health Study Program, Dhyana Pura University

Keywords:

Spermatids 7 & 19, Spermatogonium A, Ngor Eggplant Extract, Spermatocyte Primary, Pakhiten

Abstract

The study about contraceptive for adult especially for men that the numbers were limited, so needed the ingredients contraceptive is derived from a plant. One of the plants that potentially becomes contraceptive is ngor eggplant because contains antifertility substances. The research has been done about granting of ngor eggplant extract inhibiting spermatogenesis in mice. The design of research used random post-test control group design by one group control, three groups by treatment and six times doing treatment again. (T0 = control group, T1 = granting extract 15%, T2 = granting extract 20%, T3 = granting extract 25%). This treatment has been done in 36 days. The result of this research showed the granting ngor eggplant extract to T1 could reduce the number of cells spermatocyte primary pakhiten and cells spermatids 7 & 19 by meaningful (P<0,05). In T2 and T3 could reduce the number spermatogonia A cells, spermatocyte primary pakhiten cells and spermatids 7 & 19 cells (P<0,05).

Downloads

Download data is not yet available.

References

Aberoumand, A. (2012). Assay of Nutritional Potential of the Fruits of Solanum indicum L. in Iran, 8(3), 923–929.

Patel,K.,Ravi,B.,Dinesh.K.2013. Medicinal significance, pharmacological activities, and analytical aspects of solasodine: A concise report of current scientific literature. mathura. Department of Pharmaceutics, Institute of Technology, Banaras Hindu University.p:92-94

Septy Yolanda. 2011. Influence of Peroral Solasodin on Testosterone Levels of Rat Blood (Rattus novergicus) Adult Male. Available at http://pasca.unand.ac.id/id/wp-content/uploads. accessed November 2014

Suarjana, N., Karmaya, I. N. M., Satriyasa, B. K., Pangkahila, J. A., & Astuti, N. P. W. (2017). The Influence of Granting Ngor Eggplant (Solanium Indicum) Extract inhibiting of Spermatogenesis in Mice (Mus Musculus). International Journal of Health Sciences (IJHS), 1(2), 12-19.

Suiraoka, I. P., Duarsa, D. P. P., Wirawan, I. D. N., & Bakta, I. M. (2017). Perception of Parents, Teachers, and Nutritionist on Childhood Obesity and Barriers to Healthy Behavior: A Phenomenological Study. International Journal of Health Sciences (IJHS), 1(2), 1-11.

Weinbauer, G.F., Luetjens, C.M., Simoni, M. and Nieschlag, E. 2010. Physiology of Testicular Function. In Andrology: Male Reproductive Health and Dysfunction. 3rd Edition. Editors Nieschlag, E. Behre, H.M., and Nieschlag, S. Springer-Verlag BerlinHeidelberg. New York

Wong, R.S.Y., 2011, Apoptosis in Cancer, from Pathogenesis to Treatment, Journal of Experimental & Clinical Cancer Research, 30(87).

Agarwal, R., Jain, P., Ghosh, M. S., & Parihar, K. S. (2017). Importance of Primary Health Care in the Society. International Journal of Health Sciences (IJHS), 1(1), 6-11.

Arsyad, K.M.1986, Possible Development of Male Contraceptives, MKI

Billaiya, R., Jain, A., Agarwal, R., & Jain, P. (2017). Introduction about Child Health Status in India. International Journal of Health Sciences (IJHS), 1(1), 12-22.

Desai, A.B., Kagathara, V.G., Joshi, H., Rangani, A.T. and Mungra, H. 2011. Evaluation of the Antiamnesic effect of Solasodine in Mice. International Journal PharmTech Research. 3(2):732-740

Hsu SH, Tsai TR, Lin CN, Yen MH, Kuo KW (2006) Solamargine purified from Solanum incanum Chinese herb triggers gene expression of human TNFR which may lead to cell apoptosis. Biochem Biophys Res Commun 229: 1-5.

Jain, P. (2017). Effect of Online Education Trend on Quality Management. International Journal of Health Sciences (IJHS), 1(1), 1-5.

Malaiya, S., Shrivastava, A., Prasad, G., & Jain, P. (2017). Impact of Medical Education Trend in Community Development. International Journal of Health Sciences (IJHS), 1(1), 23-27.

Parihar, K. S., Dahiya, R., Billaiya, R., & Jain, P. (2017). Effect of Nuclear Family in Participation of Activities. International Journal of Health Sciences (IJHS), 1(1), 28-35.

Published

31-08-2017

How to Cite

Suarjana, N., Karmaya, I. N. M., Satriyasa, B. K., Pangkahila, J. A., & Astuti, N. P. W. (2017). The influence of granting ngor eggplant (solanium indicum) extract inhibiting of spermatogenesis in mice (mus musculus). International Journal of Health Sciences, 1(2), 12–19. https://doi.org/10.21744/ijhs.v1i2.35

Issue

Section

Peer Review Articles