Comparative study of postpartum correction of anaemia by iron sucrose vs blood transfusion
Keywords:
anaemia, blood transfusion, iron deficiency, iron sucrose, mean corpuscular volume, serum ferritin levelsAbstract
Aim: The aim of the study is to know whether intravenous iron sucrose can be a better alternative in terms of safety and efficacy over blood transfusion in the treatment of anaemia in post-partum. Materials and methods: This are prospective study is conducted in obstetrics and gynaecology Department . All these women are randomly assigned (50 women total , 25 in each group) to receive either 2 doses of intravenous iron sucrose(Group A) or blood transfusion (Group B). Haemoglobin, hemocrit, mean corpuscular volume and serum ferritin estimation is done before treatment and after 1 wk. of correction in both groups to note the improvement in values and monitored for adverse reactions. Results: There is statically significant rise in haemoglobin , hemocrit , mean corpuscular volume , and serum ferritin levels when compared to baseline after 1 week of treatment in both groups. Statistically insignificant rise in mean Hb,Hct was observed when iron sucrose group is compared to blood transfusion group. Conclusion: Intravenous iron sucrose is safe , efficacious and cost-effective treatment for post-partum anaemia. It may be an attractive to blood transfusion which may be associated with minor and major reactions.
Downloads
References
Cançado, R. D., & Muñoz, M. (2011). Intravenous iron therapy: how far have we come?. Revista brasileira de hematologia e hemoterapia, 33, 461-469.
Giannoulis, C., Daniilidis, A., Tantanasis, T., Dinas, K., & Tzafettas, J. (2009). Intravenous administration of iron sucrose for treating anemia in postpartum women. Hippokratia, 13(1), 38.
Holm, C., Thomsen, L. L., Norgaard, A., & Langhoff?Roos, J. (2017). Single?dose intravenous iron infusion versus red blood cell transfusion for the treatment of severe postpartum anaemia: a randomized controlled pilot study. Vox sanguinis, 112(2), 122-131.
Jimenez, K., Kulnigg-Dabsch, S., & Gasche, C. (2015). Management of iron deficiency anemia. Gastroenterology & hepatology, 11(4), 241.
Khamaiseh, K., Tahat, Y., Shreideh, Z., & Quran, F. (2011). Intravenous Iron Sucrose vs. Blood Transfusion in the Management of Symptomatic Post Partum Iron Deficiency Anaemia. Journal of the Royal Medical Services, 18(1), 15.
Lauwers, J. (2007). Mentoring and precepting lactation consultants. Journal of Human Lactation, 23(1), 10-11.
Milman, N. (2011). Postpartum anemia I: definition, prevalence, causes, and consequences. Annals of hematology, 90(11), 1247-1253.
Milman, N. (2012). Postpartum anemia II: prevention and treatment. Annals of hematology, 91(2), 143-154.
Niranjana, R. & Rajeswari, K. (2018). Study of effectiveness, tolerability and safety of intravenous iron sucrose in iron deficiency anaemia in postnatal women. International Journal of Reproduction, Contraception, Obstetrics and Gynecology.
Patange, R. P., & Sheth, V. K. (2014). A comparative study of injectable iron-sucrose versus oral iron in postpartum moderate anemia patients. Journal of Evolution of Medical and Dental Sciences, 3(12), 3097-3107.
Tandon, R., Jain, A., & Malhotra, P. (2018). Management of iron deficiency anemia in pregnancy in India. Indian Journal of Hematology and Blood Transfusion, 34(2), 204-215.
Thurn, L., Wikman, A., Westgren, M., & Lindqvist, P. G. (2019). Incidence and risk factors of transfusion reactions in postpartum blood transfusions. Blood Advances, 3(15), 2298-2306.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
