Lymphocytic thyroiditis
A correlation between cytological grading and thyroid function tests
Keywords:
cytological grading, fine needle aspiration (FNA), hashimoto’s thyroiditis, lymphocytic thyroiditis, thyroid functionAbstract
Sixty five cases of chronic lymphocytic thyroiditis were included in the study. Most of the study subjects were females [61 cases (94%)] and male to female ratio was 1:15. The most common age group was ? 40 years (52 cases, 80%). Grade I lymphocytic thyroiditis was observed in seventeen (17 cases, 26%) cases, Grade II in twenty eight cases (28 cases, 43.07%) and Grade III thyroiditis was seen in twenty (20 cases, 31%) cases. Anti-TPO and TSH values were increased in 95% (19/20) of cases with grade 3 lymphoid infiltrate, 92.8% (26/28) of cases with grade 2, and 94.1% (16/17) of cases with grade 1. The diagnosis of Hashimoto Thyroiditis should be based on a multidisciplinary approach wherein clinical, radiological, biochemical, cytological, and radionuclide parameters are taken into consideration. However, in spite of the availability of different diagnostic modalities, demonstration of lymphocytic infiltration on cytologic smears still remains the gold standard.
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References
Amino, N., Tada, H., & Hidaka, Y. (1999). Postpartum autoimmune thyroid syndrome: a model of aggravation of autoimmune disease. Thyroid, 9(7), 705-713.
Anila, K. R., Nayak, N., & Jayasree, K. (2016). Cytomorphologic spectrum of lymphocytic thyroiditis and correlation between cytological grading and biochemical parameters. Journal of Cytology/Indian Academy of Cytologists, 33(3), 145.
Bhardwaj, A., Kumar, R., & Acharya, S. (2019). Cytomorphic Study of Lymphocytic Thyroiditis: A Correlation between Cytological Grade and Biochemical Parameters. Journal of Clinical & Diagnostic Research, 13(6).
Bhatia, A., Rajwanshi, A., Dash, R. J., & Mittal, B. R. (2007). Lymphocytic Thyroiditis–is cytological grading significant? A correlation of grades with clinical, biochemical, ltrasonographic and radionuclide parameters. Cytojournal, 4, 10.
Dayan, C. M., & Daniels, G. H. (1996). Chronic autoimmune thyroiditis. New England journal of medicine, 335(2), 99-107.
Guarda, L. A., & Baskin, H. J. (1987). Inflammatory and lymphoid lesions of the thyroid gland: cytopathology by fine-needle aspiration. American journal of clinical pathology, 87(1), 14-22.
Kocjan, G. (2006). Fine needle aspiration cytology: diagnostic principles and dilemmas. Springer Science & Business Media.
Kumar, N., Ray, C., & Jain, S. (2002). Aspiration cytology of Hashimoto's thyroiditis in an endemic area. Cytopathology, 13(1), 31-39.
Orell, S. R., Sterrett, G. F., & Whitaker, D. (2005). Fine needle aspiration cytology. Churchill Livingstone.
Pradhan, S. P., Choudhury, S., Dash, A., & Mishra, D. P. (2016). Cytomorphological And Serological Studies In Hashimoto? S Thyroiditis.
Singh, N., Kumar, S., Negi, V. S., & Siddaraju, N. (2009). Cytomorphologic study of Hashimoto's thyroiditis and its serologic correlation: a study of 150 cases. Acta cytologica, 53(5), 507-516.
Sood, N., & Nigam, J. S. (2014). Correlation of fine needle aspiration cytology findings with thyroid function test in cases of lymphocytic thyroiditis. Journal of thyroid Research, 2014.
Uma, P., Kartheek, B. V. S., Himaja, S., Lekha, J. C., Babu, A. K., & Lakshmi, A. B. (2013). Lymphocytic thyroiditis: a correlation of cytological grades with clinical, biochemical and ultrasound findings.
Weetman, A. P., & McGregor, A. M. (1994). Autoimmune thyroid disease: further developments in our understanding. Endocrine reviews, 15(6), 788-830.
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