Assessment of effectiveness of Ozonated olive oil fused with corticosteroids for the management of oral erosive lichen planus: A novel approach

Akansha Budakoti; Anuridhi Choudhary; Nidhi Puri; Aayushi Gaur; Chandramani B. More; Kaveri Surya Khanna

doi:10.53730/ijhs.v6nS1.4879

Authors

Akansha Budakoti Senior Lecturer, Department of Oral Medicine and Radiology, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara, Gujarat, India
Anuridhi Choudhary Senior Lecturer, Department of Oral Medicine and Radiology, Faculty of Dental Sciences, SGT University, Gurugram, India
Nidhi Puri
drnidhipuri16@gmail.com
Professor, Department of Oral Medicine and Radiology, I.T.S- Centre for Dental Studies AND Research, Muradnagar, Ghaziabad, U.P, India
Aayushi Gaur Senior Lecturer, Department of Oral Medicine and Radiology, Shri Bankey Bihari Dental College &Research Center, Masuri, Ghaziabad, U.P, India
Chandramani B. More Professor, Department of Oral Medicine and Radiology, K.M. Shah Dental College and Hospital, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara, Gujarat, India
Kaveri Surya Khanna Senior Lecturer, Department of Oral Pathology and Microbiology, Yamuna Institute of Dental Sciences and Research, Gadholi, Yamunanagar, Haryana, India

Keywords:

combined therapy, corticosteroids, lycopene, oral lichen planus, ozonated therapy

Abstract

Erosive lichen planus is counted amongst the most debilitating conditions of oral cavity which has multifactorial etiology and malignant turnover potential. It has been documented that ozonated olive oil have healing, anti-inflammatory, antimicrobial and antioxidant properties and thus have great potential in management of the ulcerative lesions. Present study is aimed to evaluate and compare the efficacy of using ozonated olive oil combined with systemic steroid and antioxidant in the management of erosive lichen planus. Materials and methods: Eighty patients with a confirmed clinical and histopathologic diagnosis of erosive OLP were randomly allocated into four groups. Group I, II, III and IV were prescribed systemic Prednisolone 40 mg/day,soft-gel capsule lycopene (6 mg/day), combination therapy of systemic steroid (40mg/day) along with ozonated olive oil and combination therapy of lycopene (16 mg/day) and ozonated olive oil respectively. OLP clinical course was assessed by measuring severity of pain, burning sensation(VAS), clinical signs(scale of Thongprasom) and efficacy of the treatment(efficacy index methods of Liu set). Patients were monitored on regular follow up.

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