Approach of Ayurveda in post COVID management
Keywords:
Ayushkwath, Post COVID syndrome, Rasayana, immunomodulatoryAbstract
COVID-19 is a respiratory illness global epidemic caused by “Severe Acute Respiratory Syndrome Coronavirus 2”. Acute post COVID syndrome lasts longer than 3 weeks after the main infection, whereas chronic post COVID syndrome lasts longer than 3 weeks after the main infection. Fatigue, dyspnea, low-grade fever, cough, tastelessness, anosmia, chest pain, myalgia, and sleep and mental disturbances are common post-COVID manifestations. The cause of post-COVID syndrome is not well understood. According to Ayurveda concepts, the symptoms of Covid-19 are similar to Vatakapha pradhan Sannipataj Jwara and there will be Dhatu-Kshaya & Agnimandya Avastha in Post-COVID 19 infection. Hence in this condition agnideepana, amapachana, brimhana and rasayana chikitsa is indicated. A Post-COVID management strategy has been issued by the MHFW's Directorate General of Health Services (EMR Division) that include Ayush Kwath, Samshamani vati or Giloy powder, Ashwagandha vati or Ashwagandha powder, Amla fruit or Amla powder, Mulethi powder, Warm Milk with Haldi, Gargling with turmeric and salt, Chyawanprash and daily practice of Yogasana, Pranayama and Meditation. Many research evidences proved that all these drugs possess anti-inflammatory, antistress, antioxidant and immunomodulatory properties which help in management of post COVID syndrome.
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References
Pneumonia of unknown cause — China: disease outbreak news. Geneva: World Health Organization, January 5, 2020 (https://www.who.int/csr/don/05-january-2020-pneumonia-of-unkown-cause-china/en/. opens in new tab).Google Scholar
Guan W, Ni Z, Yu H, et al.Clinical characteristics of 2019 novel coronavirus infection in China. medRxiv preprint posted online on Feb. 9, 2020; 10.1101/2020.02.06.20020974. [CrossRef]]
van Doremalen N, Bushmaker T, Morris DH, et al. Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1. The New England Journal of Medicine. 2020 Apr;382(16):1564-1567. DOI: 10.1056/NEJMc2004973.]
National Institute of Health Director’s blog. Post-COVID syndrome. Available at https:// directorsblog.nih.gov/ tag/ post- COVID- syndrome/(Accessed March 15, 2021).
Greenhalgh T, Knight M, A’Court C, Buxton M, Husain L. Management of post-acute COVID-19 in primary care. BMJ 2020;370. doi:10.1136/bmj.m3026.
Nabavi N. Long COVID: How to define it and how to manage it. BMJ 2020;370:m3489.
Pavli et al. , Post-COVID syndrome: Incidence, clinical spectrum, and challenges for primary healthcare professionals, Archives of Medical Research, https:// doi.org/ 10.1016/ j.arcmed.2021.0]
Updated estimates of the prevalence of long COVID symptoms - Office for NationalStatistics.https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/healthandlifeexpectancies/adhocs/12788updatedestimate-softheprevalenceoflongCOVIDsymptoms(accessed March 9, 2021).
Havervall, S.; Rosell, A.; Phillipson, M.; Mangsbo, S.M.; Nilsson, P.; Hober, S.; Thelin, C. Symptoms and functional impairment assessed 8 months after mild COVID-19 among health care workers. JAMA 2021. [CrossRef]].
Maltezou HC, Pavli A, Tsakris A. Post-COVID Syndrome: An Insight on Its Pathogenesis. Vaccines. 2021 May;9(5):497.]
Greenhalgh T, Knight M, Buxton M, Husain L. Management of post-acute COVID-19 in primary care. bmj. 2020 Aug 11;370.]
Microsoft Word - Mental health considerations 2020-02-14e_en_19MARCH2020_marissa.docx (who.int)]
Anonymous, Sushrut Samhita, Sutra Stanam, 35th Chapter, 19th Sloka, 1998.
Anonymous, Charaka Samhita, Chikitsa Stanam, 30th Chapter, 291st -292nd Sloka, 1998.
Anonymous, Charaka Samhita, Sutra Stanam, 18th Chapter, 44-47th Sloka, 1992.
Thakare, Seema Himmatrao; Jumade, Prashil Prakashrao.Janapadodhwamsa in ayurveda & its comparison with recent COVID-19 pandemic, Int. J. Res. Pharm. Sci. ; Special Issue 1(11): 297-303
Yadav M, Mangal G, Garg G. COVID-19- Understanding the emerging viral disease through the concepts of Ayurveda. J Ayurveda [serial online] 2020 [cited 2021 Feb 24];14:16-21. Available from: http://www.journayu.in/text.asp?2020/14/4/16/304887
Post COVID management protocol. Ministry of Health & Family Welfare: Dehli; 13th September, 2020. Available from: https://www.ayush.gov.in/docs/PostCOVID13092020.pdf
Gautam S et al., Immunity against COVID-19: Potential role ofAyush Kwath, J Ayurveda Integr Med, https://doi.org/10.1016/j.jaim.2020.08.003
Efficacy and safety of Guduchi Ghan Vati in asymptomatic and mild to moderate cases of COVID-19: A randomized controlled pilot study. Available from: https://osf.io/c8f9h
AYUSH-64 as add-on to standard care in asymptomatic and mild cases of COVID-19: A randomized controlled trial. Available from: https://osf.io/pgraf/
An Open label prospective interventional study to assess the prophylactic effect of Guduchi GhanVati in COVID-19: A community-based study in a containment zone of Himachal Pradesh, India.
Wajpeyi SM. Ayush ministry’s health advisory in COVID-19-a critical review. International Journal of Research in Pharmaceutical Sciences. 2020 Mar 11;11(Special Issue 1).
Kumar V, Dhanjal JK, Bhargava P, Kaul A, Wang J, Zhang H, et al. Withanone and Withaferin-A are predicted to interact with transmembrane protease serine 2 (TMPRSS2) and block entry of SARS-CoV-2 into cells. J Biomol Struct Dyn 2020:1-3
Milind Abhimanyu Nisargandha et al., Role of Ashwagandha (Withania Somnifera) as Immunomodulator in Coronavirus in a pandemic – A systemic review Int. J. Res. Pharm. Sci., 2020, 11 (SPL)(1), 1649-1654
Sharma PV. Dravyaguna Vigyan-vol-II. Varanasi: Chaukhambha Bharti Academy, reprint; 2013. p. 162.
Khare CP., Indian Medicinal Plants - An Illustrated Dictionary. Delhi: Springer; 2007. p. 187.
Liu Z, Ying Y. The inhibitory effect of curcumin on virus induced cytokine storm and its potential use in the associated severe pneumonia. Front Cell Dev Biol 2020;8:479.
Wen CC, Kuo YH, Jan JT, Liang PH, Wang SY, Liu HG, et al. Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus. J Med Chem 2007;50:4087-95.
Sharma PV. Dravyaguna Vigyan-vol-II. Varanasi: ChaukhambhaBharti Academy, Reprint; 2013. p. 761.
Sagar V, Kumar AH. Efficacy of natural compounds from Tinospora cordifolia against SARS-CoV-2 protease, surface glycoprotein and RNA polymerase. BEMS Rep 2020;6:6-8.
Sharma PV. Dravyaguna Vigyan-vol-II. Varanasi: Chaukhambha Bharti Academy, Reprint; 2013. p. 758.
Sharma PV, editor. Mahendra Bhogik, Guduchyadi Varga, Dhanvantari Nighantu. Varanasi: Chaukhambha Orientalia, Reprint; 2016. p. 55.
Sai Ram M, Neetu D, Yogesh B, Anju B, Dipti P, Pauline T, et al. Cyto-protective and immunomodulating properties of Amla (Emblica officinalis) on lymphocytes: An Invitro study. J Ethnopharmacol 2020;81:5-10.
Rathi B, Rathi R, Ade V, Pargaonkar A. Chyavanprash: Choice of drug for immunity boosting and health supplements during COVID-19 pandemic. International Journal of Research in Pharmaceutical Sciences. 2020;11 (SPL)(1):1346-1350
Anil, M., and Suresh, P. (2011). Determination of free radical scavenging activity in herbal supplement: chyawanprash. Int. J. Drug Dev. Res. 3 (1), 328–333.)
Bhattacharya et al., 2002 Bhattacharya, S. K., Bhattacharya, D., Sairam, K., and Ghosal, S. (2002). Effect of bioactive tannoid principles of Emblica officinalis on ischemia-reperfusion-induced oxidative stress in rat heart. Phytomed. 9 (2), 171–174. doi:10.1078/0944-7113-00090)
Kataria S, Sharma P, Ram JP, Deswal V, Singh M, Rana R, Singhal R, Tripathi A, Kumar K, Trehan N. A Pilot Clinical study of an add on Ayurvedic formulation containing Guduchi and Pippali in mild to moderate COVID-19. Journal of Ayurveda and Integrative Medicine. 2021 Jun 10.
Khabade S, Rathi B, Rathi R. The relevance of dietetic approach of ayurveda from the perspective of COVID-19 pandemic. International Journal of Research in Pharmaceutical Sciences. 2020, 11 (SPL)(1), 748-752
Sneha Dhakite and Sadhana Misar Wajpeyi, Role of Rasayana in Prevention of COVID-19 - A Review ,Int. J. Res. Pharm. Sci., 2020, 11 (SPL)(1), 716-722
Gupta K, Singhal A. Clinical Study in the Management of Post COVID Syndrome. Clinical Study. 2021 May;2(3).
Talwar D, Madaan S, Kumar S, Jaiswal A, Khanna S, Hulkoti V, et al. Post COVID hypothalamic- pituitary-adrenal axis dysfunction manifesting as perinatal depression: A case series. MEDICAL SCIENCE. 2021 Jun;25(112):1402–6.
Hepat S, Wadekar A, Goyal A, Shukla S, Acharya S, Kumar S. Garcin syndrome: A rare complication of rhinocerebral mucormycosis in post COVID patient. MEDICAL SCIENCE. 2021 Jul;25(113):1788–94.
Patel M, Talwar D, Kumar S, Acharya S, Dubey A, Hulkoti V, et al. Cutaneous mucormycosis with maxillary sinus fistula as a presenting feature of COVID-19: A rare case report. MEDICAL SCIENCE. 2021 Jul;25(113):1507–12.
Gondivkar SM, Indurkar A, Degwekar S, Bhowate R. Evaluation of gustatory function in patients with diabetes mellitus type 2. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2009 Dec 1;108(6):876-80.
Walia IS, Borle RM, Mehendiratta D, Yadav AO. Microbiology and antibiotic sensitivity of head and neck space infections of odontogenic origin. Journal of maxillofacial and oral surgery. 2014 Mar 1;13(1):16-21.
Lohe VK, Degwekar SS, Bhowate RR, Kadu RP, Dangore SB. Evaluation of correlation of serum lipid profile in patients with oral cancer and precancer and its association with tobacco abuse. Journal of oral pathology & medicine. 2010 Feb;39(2):141-8.
Korde S, Sridharan G, Gadbail A, Poornima V. Nitric oxide and oral cancer: A review. Oral oncology. 2012 Jun 1;48(6):475-83.
Gondivkar SM, Gadbail AR. Gorham-Stout syndrome: a rare clinical entity and review of literature. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2010 Feb 1;109(2):e41-8.
Gadbail AR, Chaudhary M, Gawande M, Hande A, Sarode S, Tekade SA, Korde S, Zade P, Bhowate R, Borle R, Patil S. Oral squamous cell carcinoma in the background of oral submucous fibrosis is a distinct clinicopathological entity with better prognosis. Journal of Oral Pathology & Medicine. 2017 Jul;46(6):448-53.
Gadre PK, Ramanojam S, Patankar A, Gadre KS. Nonvascularized bone grafting for mandibular reconstruction: myth or reality?. Journal of Craniofacial Surgery. 2011 Sep 1;22(5):1727-35.
Sorte K, Sune P, Bhake A, Shivkumar VB, Gangane N, Basak A. Quantitative assessment of DNA damage directly in lens epithelial cells from senile cataract patients. Molecular vision. 2011;17:1.
Basak S, Rajurkar MN, Mallick SK. Detection of Blastocystis hominis: a controversial human pathogen. Parasitology research. 2014 Jan;113(1):261-5.
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