Efficiency of prophylactic antibiotic coverage prior dental implant surgery: An original research

Priyanka Bhagat; Deepak Ningombam Singh; J Mahesh; Rethi Gopakumar; Surbhi Sharma; N. Alwithanani; Rahul VC Tiwari

doi:10.53730/ijhs.v6nS1.5129

Authors

Priyanka Bhagat Senior lecturer, Department of Conservative Dentistry and Endodontics, Seema Dental college and Hospital Rishikesh
Deepak Ningombam Singh Assistant Professor, Department of Oral Medicine and Radiology Dental College, Regional Institute of Medical Sciences, Imphal, Manipur
Mahesh J Professor and Head, Dept. Of Periodontics, Noorul Islam College of Dental Sciences,Trivandrum, Kerala
Rethi Gopakumar Reader, Dept of Conservative Dentistry and Endodontics, Noorul Islam College of Dental Sciences, Trivandrum, Kerala
Surbhi Sharma Genesis institute of Dental sciences and Research, Ferozepur, Baba Farid university of health sciences and research
N. Alwithanani Assistant Professor, Department of Oral and maxillofacial Surgery and diagnostic science, Taif University, Taif, Saudi Arabia
Rahul VC Tiwari
drrahulvctiwari@gmail.com
PhD Scholar, Dept of OMFS, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, 384315

Keywords:

Antibiotic prophylaxis habits, Oral implant surgery, Postoperative infection, Bacterial resistance

Abstract

Purpose of the present study was to determine whether antibiotic prophylaxis is an effective and popular treatment aid in conjunction with oral implant placement in healthy patients. Observational cross-sectional study was conducted based on a web-survey reported according to the STROBE guidelines. A questionnaire was sent via email to each participant. It contained close-ended and some open-ended questions concerning demographics, antibiotic type, prescription duration and dosage which was analysed statistically using SPSS 25.0. Approximately 84% routinely prescribed prophylactic antibiotics in conjunction with oral implant surgery, 15.6% prescribed antibiotics in certain situations and only 1 did not prescribe antibiotics at all. Overall, 116 respondents prescribed both pre- and postoperative antibiotics, 29 prescribed antibiotics only preoperatively and 14 prescribed antibiotics exclusively after surgery. High range of prophylactic regimens is prescribed and they are not adhering to the new science-based specifications. Guidelines focused on the indications for prophylactic antibiotics among healthy patients are required to prevent bacterial resistance, side effects and costs caused by overtreatment and the irrational use of antibiotics.

Downloads

Download data is not yet available.

References

Ahmad N, Saad N. Effects of Antibiotics on Dental Implants: A Review. J Clin Med Res 2012; 4: 1–6.

Xu L, Wang Y, Nguyen V T, Chen J. Effects of Topical Antibiotic Prophylaxis on Wound Healing After Flapless Implant Surgery: A Pilot Study. J Periodontol 2016; 87: 275–280.

El-Kholey K E. Efficacy of two antibiotic regimens in the reduction of early dental implant failure: a pilot study. Int J Oral Maxillofac Surg 2014; 43: 487–490.

Guillaume B. Dental implants: a review. Morphologie. 2016;100:189–98. https://doi.org/10.1016/j.morpho.2016.02.002.

Esposito M, Grusovin MG, Worthington HV. Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications. Cochrane Database Syst Rev. 2013;31:CD004152. https://doi. org/10.1002/14651858.CD004152.pub4.

Pye AD, Lockhart DE, Dawson MP, Murray CA, Smith AJ. A review of dental implants and infection. J Hosp Infect. 2009;72:104–10. https://doi.org/10. 1016/j.jhin.2009.02.010.

Tan WC, Ong M, Han J, Mattheos N, Pjetursson BE, Tsai AY, Sanz I, et al. Effect of systemic antibiotics on clinical and patient reported outcomes of implant therapy – a multicenter randomized controlled clinical trial. Clin Oral Implants Res. 2014;25:185–93. https://doi.org/10. 1111/clr.12098.

Arduino PG, Tirone F, Schiorlin E, Esposito M. Single preoperative dose of prophylactic amoxicillin versus a 2-day postoperative course in dental implant surgery. A two-Centre randomised controlled trial. Eur J Oral Implantol. 2015;8:143–9.

Caiazzo A, Casavecchia P, Barone A, Brugnami F. A pilot study to determine the effectiveness of different amoxicillin regimens in implant surgery. J Oral Implantol. 2011;37:691–6. https://doi.org/10.1563/AAID-JOI-D-09-00134.1.

Rodríguez Sánchez F, Rodríguez Andrés C, Arteagoitia I. Which antibiotic regimen prevents implant failure or infection after dental implant surgery? A systematic review and meta-analysis. J Craniomaxillofac Surg. 2018;46: 722–36. https://doi.org/10.1016/j.jcms.2018.02.004.

Ahmad N. Effects of antibiotics on dental implants: a review. J Clin Med Res. 2012;4:1–6. https://doi.org/10.4021/jocmr658w.

Ata-Ali JAA, Ata-Ali F, Ata-Ali F. Do antibiotics decrease implant failure and postoperative infections? A systematic review and metaanalysis. Int J Oral Maxillofac Surg. 2014;43:68–74. https://doi.org/10.1016/j.ijom.2013.05.019.

Chrcanovic B, Albrektsson T, Wennerberg A. Prophylactic antibiotic regimen and dental implant failure: a meta-analysis. J Oral Rehabil. 2014;41:941–56. https://doi.org/10.1111/joor.12211.

Lund B, Hultin M, Tranaeus S, Naimi-Akbar A, Klinge B. Complex systematic review – perioperative antibiotics in conjunction with dental implant placement. Clin Oral Implants Res. 2015;11:1–14. https://doi.org/10.1111/clr.12637.

Park J, Tennant M, Walsh LJ, Kruger E. Is there a consensus on antibiotic usage for dental implant placement in healthy patients? Aust Dent J 2017;0: 1–9. doi: https://doi.org/10.1111/adj.12535.

AbuKaraky AE, Afifeh KA, Khatib AA, Khdairi NO, Habarneh HM, Ahmad WKH, et al. Antibiotics prescribing practices in oral implantology among jordanian dentists. A cross sectional, observational study. BMC Res Notes. 2011;4:266. https://doi.org/10.1186/1756-0500-4-266.

Ireland RS, Palmer NO, Lindenmeyer A, Mills N. An investigation of antibiotic prophylaxis in implant practice in the UK. Br Dent J. 2012;213:E14. https:// doi.org/10.1038/sj.bdj.2012.960.

Khalil D, Hultin M, Andersson Fred L, Parkbring Olsson N, Lund B. Antibiotic prescription patterns among Swedish dentists working with dental implant surgery: adherence to recommendations. Clin Oral Implants Res. 2015;26:1064–9. https://doi.org/10.1111/clr.12402.

Pyysalo M, Helminen M, Antalainen AK, Sándor GK, Wolff J. Antibiotic prophylaxis patterns of Finnish dentists performing dental implant surgery. Acta Odontol Scand. 2014;72:806–10. https://doi.org/10.3109/00016357.2014.913194.

Deeb GR, Soung GY, Best AM, Laskin DM. Antibiotic prescribing habits of Oral and maxillofacial surgeons in conjunction with routine dental implant placement. J Oral Maxillofac Surg. 2015;73:1926–31. https://doi.org/10.1016/j.joms.2015.05.024.

Arteagoitia I, Rodríguez-Andrés C, Rodríguez-Sánchez F. Antibiotic prophylaxis habits in dental implant surgery among dentists in Spain. A cross-sectional survey. Med Oral Patol Oral Cir Bucal. 2018;23(5):e608–18. https://doi.org/10.4317/medoral.22626.

Review on Antimicrobial Resistance. Tackling Drug-resistant Infections Globally: Final Report and Recommendations. 2016. https://amr-review/ org/sites/default/files/160525_Final%20paper_with%20cover.pdf

Marra F, George D, Chong M, Sutherland S, Patrick DM. Antibiotic prescribing by dentists has increased: why? J Am Dent Assoc. 2016;147:320–7. https://doi.org/10.1016/j.adaj.2015.12.014.

Giargia M, Scotti E, Marchetti S, Mensi M. The use of antibiotics: data analysis of a survey among a sample of italian dentists. Dent Cadmos. 2018; 86(3):204–13. https://doi.org/10.19256/d.cadmos.03.2018.06.

Escalante M G, Eubank T D, Leblebicioglu B, Walters J D. Comparison of Azithromycin and Amoxicillin Before Dental Implant Placement: An Exploratory Study of Bioavailability and Resolution of Postoperative Inflammation. J Periodontol 2015; 86: 1190–1200.

Tomás Carmona P, Diz Dios C, Scully C. Efficacy of Antibiotic Prophylactic Regimens for the Prevention of Bacterial Endocarditis of Oral Origin. J Dent Res 2007; 86: 1142–1159.