Role of MRI with diffusion and whole tumor volume calculation in detection of response in rectal cancer patients under therapy

https://doi.org/10.53730/ijhs.v6nS1.5242

Authors

  • Laila A Mohsen Associate Professor of Radiology, Radiology Department, Faculty of Medicine, El Minia University, El Minia, Egypt
  • Moustafa Abdel Kader Professor of Radiology, Radiology Department, Faculty of Medicine, El Minia University, El Minia, Egypt
  • Amany Saber Gergis Professor of Clinical Oncology, Faculty of Medicine, El Minia University, El Minia, Egypt
  • Ahmed Mahrous Sayed Radiology specialist, Radiology Department, Minia Oncology Center, El Minia, Egypt

Keywords:

Colorectal cancer, Magnetic resonance, cancer rectum, perirectal, pelvic

Abstract

Background: MRI examination of the rectum has evolved as the standard technique in the assessment of cancer rectum having multiplaner capabilities and high tissue contrast imaging. The aim of this study: The aim of this study is to evaluate the role of MRI in assessment of rectal neoplasm. Patients and methods: In this study we prospectively evaluated 40 patients (24 male -60%) and (16 females -40%), who referred to the MRI unit, Radiology department, (Minia Oncology Center) for further assessment of  histopathology proven rectal carcinoma, during the period of (August 2019 ) to (August 2021). Results: 10% of patients (4 participants) had high rectal cancer while 55% of them (22 patients) had middle rectal cancer. On the other hand, 35% of them (14 patients) had low rectal cancer. 85% of participants (34 patients) were diagnosed as adenocarcinoma while the remaining 6 participants (15% of patients) were diagnosed as mucinous adenocarcinoma. 77.5% of patients (31 participants) had grade II rectal cancer while 9 patients (22.5% of participants) were diagnosed as grade III rectal cancer. On performing TNM staging, we found that the majority of cases; 37.5% of participants (15 patients); were found to be in stage IIA.

Downloads

Download data is not yet available.

References

Natally Horvat, Carlos Tavares Rocha C, Clemente Oliveira B, Et al. (2019). MRI of Rectal Cancer: Tumor Staging, Imaging Techniques, and Management, RadioGraphics, 39: 367–387.

Kaur H, Choi H, You YN. (2012). MR imaging for preoperative evaluation of primary rectal cancer: practical considerations. RadioGraphics, 32(2):389–409.

Maas M, Lambregts DM, Nelemans PJ. (2015). Assessment of clinical complete response after chemoradiation for rectal cancer with digital rectal examination, endoscopy, and MRI: selection for organ-saving treatment. Ann Surg Oncol, 22(12): 3873–3880.

Siegel, R., Desantis, C. & Jemal, A. (2014a). Colorectal cancer statistics, 2014. CA Cancer J Clin, 64(2), 104-17.

Siegel, R., Ma, J., Zou, Z. (2014b). Cancer statistics, 2014. CA Cancer J Clin, 64(1), 9-29.

Vlad, C., Kubelac, P., Vlad, D. (2015). Evaluation of clinical, morphopathological and therapeutic prognostic factors in rectal cancer. Experience of a tertiary oncology center. J buon, 20(1), 92-9.

Lee, E. S., Kim, M. J., Park, S. C. (2018). Magnetic Resonance Imaging-Detected Extramural Venous Invasion in Rectal Cancer before and after Preoperative Chemoradiotherapy: Diagnostic Performance and Prognostic Significance. European Radiology, 28(2): 496-505.

Tawadros, P. S., Paquette, I. M., Hanly, A. M. (2015). Adenocarcinoma of the rectum in patients under age 40 is increasing: impact of signet-ring cell histology. Diseases of the Colon & Rectum, 58(5), 474-478.

Phillips, K. A., Liang, S. Y., Ladabaum, U. (2007). Trends in colonoscopy for colorectal cancer screening. Med Care, 45(2), 160-7.

Jemal, A., Siegel, R., Xu, J. (2010). Cancer statistics, 2010. CA Cancer J Clin, 60(5), 277-300.

Paquette, I. M. Atkinson, S. J. (2019). The epidemiology of rectal cancer. Comprehensive Rectal Cancer Care. Springer.

Liu, L., Liu, Y., Xu, L. (2017). Application of texture analysis based on apparent diffusion coefficient maps in discriminating different stages of rectal cancer. Journal of Magnetic Resonance Imaging, 45(6), 1798-1808.

Kuo, L.-J., Liu, M.-C., Jian, J. J.-M. (2007). Is Final TNM Staging A Predictor for Survival in Locally Advanced Rectal Cancer after Preoperative Chemoradiation Therapy? Annals of Surgical Oncology, 14(10), 2766-2772.

Schmoll, H., Van Cutsem, E., Stein, A. (2012). ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making. Annals of oncology, 23(10), 2479-2516.

Al-Sukhni, E., Milot, L., Fruitman, M. (2012). Diagnostic accuracy of MRI for assessment of T category, lymph node metastases, and circumferential resection margin involvement in patients with rectal cancer: a systematic review and meta-analysis. Annals of surgical oncology, 19(7), 2212-2223.

Published

01-04-2022

How to Cite

Mohsen, L. A., Kader, M. A., Gergis, A. S., & Sayed, A. M. (2022). Role of MRI with diffusion and whole tumor volume calculation in detection of response in rectal cancer patients under therapy. International Journal of Health Sciences, 6(S1), 2818–2824. https://doi.org/10.53730/ijhs.v6nS1.5242

Issue

Section

Peer Review Articles