Determination of dutasteride in pure and tablet by flow injection system
Keywords:
determination, dutasteride (DS), flaw injection, injection system, linearityAbstract
A new Spectrophotometric flaw injection method has been established for the determination of Dutasteride (DS) in Pure and pharmaceutical tablets preparations. The method was based on the interaction of Dutasteride, as an n-electron donor with Chloranil as a π-acceptor, in acetonitrile to give reddish orange colored Chloranil radical anion with absorption maxima at 525 nm. The linearity of this method was in the range of (0.9948-8.932) ug.ml' with a correlation coefficient of 0.9969, a relative standard deviation (RSD) 0.422 %, with detection limit of (0.420) ug.ml".
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