Comparative evaluation of anti-inflammatory activity of Shodhana processed Guggul

Poonam P. Taru; Vivek B. Ingale; Sabeena Sayed; Sachin Sakat; Om Bagade; Neeta Rai

doi:10.53730/ijhs.v6nS1.5471

Authors

Poonam P. Taru
poonam.taru@vupune.ac.in
Assistant Professor, Vishwakarma University, School of pharmacy, Kondhwa Pune, Maharashtra, India
Vivek B. Ingale Assistant professor, PDEA's Shankarrao Ursal College of Pharmaceutical Sciences And Research Centre, Pune, Maharashtra, India
Sabeena Sayed Assistant Professor, Vishwakarma University, School of pharmacy, Kondhwa Pune, Maharashtra, India
Sachin Sakat Associate professor, Vishwakarma University, School of pharmacy, Kondhwa Pune, Maharashtra, India
Om Bagade Associate professor, Vishwakarma University, School of pharmacy, Kondhwa Pune, Maharashtra, India
Neeta Rai Assistant Professor, Vishwakarma University, School of pharmacy, Kondhwa Pune, Maharashtra, India

Keywords:

Shodhana, guggul, Carrageenan, Freund’s Adjuvant, Triphala kwath

Abstract

Shodhana is a technique that has been around since the Samhita period. Shodhana is an Ayurvedic purification treatment that involves soaking, rubbing, and washing hazardous medicinal herbs (upavishadravyas) with specialised media such as gomutra (cow's urine), Godugdha (cow's milk), Guduchi Kwath, Triphala Kwath, Pancha Tikta Kwath, Dash Moola Kwath, Nimba Patra Kwatha with Haridra Churna, Nirgundi Patra and other pharmaceutical procedures to remove the doshas. Shodhana is a significant approach for removing Doshas from practically all types of medications (impurities or toxic contents) and substances are then processed further. In the present study guggul is used and guggulu shodhana is done by using different liquid media such as distilled water, Gomutra (cow urine), Triphala Kwath. The present study aimed to determine the anti-inflammatory activity of shodhit guggul by using carrageenan-induced paw edema and Freund's adjuvant-induced arthritis in in Wistar Albino rats. By the pharmacological study it is concluded that the Triphala shodhit Guggul showed enhanced anti-inflammatory activity as compared with Distilled water and Gomutra shodhit Guggul. Thus, the purpose of Shodhana process of Guggul is proved experimentally showing enhancement of pharmacological activity.

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