Study of HbA1c in iron deficiency anemic non diabetic subjects
Keywords:
iron deficiency, anemia, glycated hemoglobin (HbA1c)Abstract
To study the effect of iron deficiency anemia on glycated hemoglobin (HbA1c) in non- diabetic Indian subjects. The present observational study was performed on minimum 100 patients attending General Medicine outpatient department. All patients presenting to General Medicine outpatient department fulfilled the inclusion and exclusion criteria enrolled in the study. An informed written consent was obtained from the patients. The detailed history was taken and necessary clinical examination was carried out in all patients. In the current study, patients with iron deficiency anaemia had a mean HbA1c of 5.86. The mean serum iron level in patients with Hb1Ac levels ranging from 4-5.6 was 24.25. The corresponding mean serum iron for HbA1c range 5.7-6.4 was 22.25. The corresponding mean serum iron for HbA1c levels greater than 6.5 was 21.96. According to the findings, there is an inverse relationship between HbA1c and mean serum iron levels, and this relationship is statistically significant (p0.05), i.e. mean serum iron decreases as HbA1c level increases. The present study concluded that the levels of HbA1c were increased significantly among patients with iron deficiency anemia. So, Iron deficiency anemia has to be kept in mind before using the HbA1c to diagnose diabetes.
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