Comparison of efficacy of three different venous occlusion duration on pre-treatment with injection ketamine to prevent propofol injection pain in patients undergoing surgery under general anaesthesia
Keywords:
propofol pain, venous occlusion, ketamineAbstract
Propofol is rapidly acting intravenous agent used for induction in general anaesthesia.It causes pain while administering,being uncomfortable to patients .So an observational study was done to compare the effects of different time duration of venous occlusion on pretreatment with injection Ketamine for prevention of pain at injection site. After approval of ethical committee and written informed consent,ASA grade I and II,60 patients of either gender, aged between 18-60 years were assigned to three groups of 20 each under GA and divided as GROUP K20,K40,and K60 according to venous occlusion duration of 20,40,and 60 seconds respectively on administration of ketamine(0.2mg/kg)as pretreatment for propofol injection pain.Following injection of ketamine ,25% dose of propofol was given and patient was asked for any sensation of pain at the site of injection and graded accordingly. Haemodynamics were compared in all the three groups. All 60 patients were reviewed for propofol pain and haemodynamics were recorded before pretreatment with ketamine and after pretreatment for 5 minutes and results evaluated through chi square test.P value was significant for 20 seconds (p value <0.001)but not for 40 and 60 seconds(p value 0.201)resulting in no difference in pain score between the two groups as compared to K20 group.
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