Injectable platelet-rich fibrin (albumin gel and liquid platelet-rich fibrin)
Keywords:
aesthetics, AlbPRF, injectable platelet plasma, PRFAbstract
This article provides review on Injectable Platelet-Rich Fibrin (Albumin Gel and Liquid Platelet-Rich Fibrin). The current findings suggest that AlbPRF has regeneration characteristics that are caused by the slow and steady release of growth factors contained in liquid PRF via albumin gel breakdown. Future research is needed to thoroughly define the degrading features of Alb-PRF in vivo and to investigate potential therapeutic uses in other domains of medicine. Platelet concentrates are easy to apply in clinical practice and offer potential benefits including rapid wound healing and bone regeneration, and can therefore be considered to be new therapeutic adjuvants. In dental implant surgery they are used in bone reconstruction prior or concomitant to implant procedures, and also for dental extraction socket preservation.
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References
Agrawal M, Agrawal V. Platelet rich fibrin and its applications in dentistry A review article. Natl J Med Dent Res 2014;2:51 8.
Chandran P, Sivadas A. Platelet rich fibrin: Its role in periodontal regeneration. Saudi J Dent Res 2014;5:117 22.
Prakash S, Thakur A. Platelet concentrates: Past, present and future. J Maxillofac Oral Surg 2011;10:45 9. 4. Sunitha Raja V, Munirathnam Naidu E. Platelet rich fibrin: Evolution of a second generation platelet concentrate. Indian J Dent Res 2008;19:42 6
Dohan D.M., Choukroun J., Diss A., Dohan S.L., Dohan A.J., Mouhyi J., Gogly B. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part I: Technological concepts and evolution. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod. 2006;101:37–44. doi: 10.1016/j.tripleo.2005.07.008. [PubMed] [CrossRef] [Google Scholar]
Strauss F.J., Stahli A., Gruber R. The use of platelet-rich fibrin to enhance the outcomes of implant therapy: A systematic review. Clin. Oral Implants Res. 2018;29(Suppl. 18):6–19. doi: 10.1111/clr.13275. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Karimi K., Rockwell H. The Benefits of Platelet-Rich Fibrin. Facial Plast. Surg. Clin. N. Am. 2019;27:331–340. doi: 10.1016/j.fsc.2019.03.005. [PubMed] [CrossRef] [Google Scholar]
Fujioka-Kobayashi M., Kono M., Katagiri H., Schaller B., Zhang Y., Sculean A., Miron R.J. Histological comparison of Platelet rich fibrin clots prepared by fixed-angle versus horizontal centrifugation. Platelets. 2020:1–7. doi: 10.1080/09537104.2020.1754382. [PubMed] [CrossRef] [Google Scholar]
Kawase T., Tanaka T. An updated proposal for terminology and classification of platelet-rich fibrin. Regen. Ther. 2017;7:80–81. doi: 10.1016/j.reth.2017.10.002. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, et al. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101(3):e45–50.
Miron RJ, Fujioka-Kobayashi M, Hernandez M, Kandalam U, Zhang Y, Ghanaati S, et al. Injectable platelet rich fibrin (i- PRF): opportunities in regenerative dentistry? Clin Oral Investig. 2017;21(8):2619–27.
Kawase T, Kamiya M, Kobayashi M, Tanaka T, Okuda K, Wolff LF, et al. The heat-compression technique for the conversion of platelet- rich fibrin preparation to a barrier membrane with a reduced rate of biodegradation. J Biomed Mater Res B Appl Biomater. 2015;103:825– 31. doi:10.1002/jbm.b.33262.
Mourão C, Gheno E, Lourenço ES, Barbosa RDL, Kurtzman GM,
Javid K, et al. Characterization of a new membrane from concentrated growth factors associated with denaturized Albumin (Alb-CGF) for clinical applications: A preliminary study. Int J Growth Factors Stem Cells Dent. 2018;1:64.
Jung SY, Kim HY, Oh HJ, Choi E, Cho MS, Kim HS. Feasibility of autologous plasma gel for tonsil-derived stem cell therapeutics in hypoparathyroidism. Sci Rep. 2018;8:11896.
Doghaim NN, El-Tatawy RA, Neinaa YME. Assessment of the efficacy and safety of platelet poor plasma gel as autologous dermal filler for facial rejuvenation. J Cosmet Dermatol. 2019;18:1271–1279.
Fujioka-Kobayashi M, Schaller B, Mourão C, Zhang Y, Sculean A, Miron RJ. Biological characterization of an injectable platelet- rich fibrin mixture consisting of autologous albumin gel and liquid platelet-rich fibrin (Alb-PRF). Platelets. 2021;32(1):74–81.
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