An observational study to compare the efficacy of dexmedetomidine versus butorphanol for balanced anaesthesia and postoperative analgesia in patients undergoing laparoscopic surgery

Sara Mary Thomas; Richa Tailor; Dinesh Chauhan; Arpit Shah

doi:10.53730/ijhs.v6nS3.5851

Authors

Sara Mary Thomas Professor, Department of Anaesthesiology, Shrimati Bhikhiben Kanjibhai Shah Medical Institute | Research Centre, Sumandeep Vidyapeeth (An Institute Deemed to be University), Piparia, Vadodara, Gujarat, India
Richa Tailor
pranav.kanabar@gmail.com
3rd year MD resident, Department of Anesthesiology, Shrimati Bhikhiben Kanjibhai Shah, Medical Institute &Research Centre, Sumandeep Vidyapeeth (An Institute Deemed to be University) Piparia, Vadodara, Gujarat, India
Dinesh Chauhan Professor & HOD, Department of Anaesthesiology, Shrimati Bhikhiben Kanjibhai Shah Medical Institute | Research Centre, Sumandeep Vidyapeeth (An Institute Deemed to be University), Piparia, Vadodara, Gujarat, India
Arpit Shah Senior Resident, Department of Anaesthesiology, Shrimati Bhikhiben Kanjibhai Shah Medical Institute | Research Centre, Sumandeep Vidyapeeth (An Institute Deemed to be University), Piparia, Vadodara, Gujarat, India

Abstract

To compare efficacy of intravenous dexmedetomidine versus butorphanol for balanced anaesthesia and postoperative analgesia in patients undergoing laparoscopic surgery under general anaesthesia. After obtaining institutional ethical committee approval & written informed consent 54 adults of either gender aged 18-60 years, of grade I & II ASA were divided into two equal groups; Group D received Inj. Dexmedetomidine 1 µg/kg i.v. & Group B, Inj. Butorphanol 10 µg/kg i.v., in 100ml NS over 10 minutes before induction. Standard general anaesthesia technique including propofol, succinylcholine/Atracurium, IPPV & Isoflurane/N20 was administered. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) & SPO2 were recorded at - baseline, after-drug administration, induction, at intubation & 1, 3 & 5 minutes after intubation, at pneumoperitoneum & 15 minutes intervals upto 30 minutes after extubation. Postoperative Visual Analog Scale (VAS) Scores & Ramsay Sedation Score (RSS) were evaluated half hourly till score of >4 & <2 were recorded, respectively.

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