A study on eosinophilic and Lymphocytic esophagitis in patients with typical gastroesophageal reflux disease symptoms

Mahasen Abd Alrahman Mabrouk; Shendy Mohammed Sherif; Mohammed Ahmed Mohey El din; Mahmoud Hassan Ali Morsy Eliouny

doi:10.53730/ijhs.v6nS2.5858

Authors

Mahasen Abd Alrahman Mabrouk Tropical Medicine Department, Faculty of Medicine, Cairo University, Egypt
Shendy Mohammed Sherif Hepatology and gastroenterology Department, Theodor Bilharz Research Institute (TBRI), Egypt
Mohammed Ahmed Mohey El din Tropical Medicine Department, Faculty of Medicine, Cairo University, Egypt
Mahmoud Hassan Ali Morsy Eliouny
Mahmoud_dr555@yahoo.com
M.Sc. Tropical medicine- Ain Shams University

Keywords:

eosinophilic esophagitis, gastroesophageal reflux, lymphocytic, gastrointestinal

Abstract

Background: Eosinophilic esophagitis (EoE) has emerged as an important gastrointestinal (GI) disorder during the last 15 years, affecting approximately 15% of patients with dysphagia EoE presents a diagnostic challenge because eosinophils are also a feature of acid-induced esophagitis.The aim of this study was to evaluate prospectively the presence of eosinophilic and lymphocytic esophagitis in patients with typical gastroesophageal reflux disease symptoms. Patients and Methods: This was a prospective study which was conducted on 200 patients, to estimate the prevalence of eosinophilic and lymphocytic esophagitis in patients with typical gastroesophageal reflux disease symptoms.Results: Regarding serum IgE as laboratory investigation, all the cases 6 (100%) diagnosed to have EoE showed elevated level of serum IgE level ((normal range was used according to the laboratory was: 0 – 165 IU/ml). There was statistical significance for the presence of elevated serum IgE level and peripheral serum eosinophilia between positive and negative cases for EoE Conclusion: Eosinophilic esophagitis is not uncommon disease and presented in 6 cases out of 200 patients having typical symptoms of GERD. All the positive EoE cases having history of allergy and most of them are asthmatic.

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