Misa, Post COVID complication
Case report & mini review
Keywords:
MISA, COVID, infectionAbstract
Multisystem inflammatory syndrome in adults (MIS-A) is an rare and underrecognised postinfectious manifestation that occurs 4–6 weeks after COVID-19 infection. Patients affected tend to be young or middle-aged, from ethnic minority backgrounds and previously healthy. The patient suffer from high fever and myalgia, and there is myriad of extrapulmonary symptoms and signs, including cardiac, gastrointestinal, neurological and dermatological involvement. Cardiovascular shock and markedly raised inflammatory markers are prominent features, while significant hypoxia is uncommon. Patients respond well to corticosteroid therapy, but failure of clinicians to recognise this recently identified phenomenon, which can mimic common conditions including sepsis, could delay diagnosis and treatment. Here we present a case of MIS-A in an adult men, with severe illness and positive test result for SARS-CoV-2 infection (PC, antigen, or antibody).There was severe extrapulmonary organ system dysfunction;There was markedly elevated acute inflammatory markers; .there was no any respiratory illness.
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Morris SB, Schwartz NG, Patel P, et al. Case Series of Multisystem InflammatorySyndrome in Adults Associated with SARS-CoV-2. Infection - United Kingdom and United States, March-August 2020. MMWR Morb Mortal Wkly Rep 2020;69:1450–6.
Malangu B, Quintero JA, Capitle EM. Adult inflammatory multi-system Syndrome mimicking Kawasaki disease in a patient with COVID-19. Cureus 2020;12:e11750.
Ahsan T, Rani B. A case of multisystem inflammatory syndrome Post-COVID- 19 infection in an adult. Cureus 2020;12:e11961.
Kofman AD, Sizemore EK, Detelich JF, et al. A young adult with COVID-19 and multisystem inflammatory syndrome in children (MIS-C)- Like illness: a case report. BMC Infect Dis 2020;20:716.
Razavi AC, Chang JL, Sutherland A, et al. A 23-year-old man with multisystem inflammatory syndrome after mild COVID-19.J Investig Med High Impact Case Rep .2020;8:2324709620974200.
Sokolovsky S, Soni P, Hoffman T, et al. COVID-19 associated Kawasaki-like multisystem inflammatory disease in an adult. Am J Emerg Med 2021;39:253.e1–e2.
Jones I, Bell LCK, Manson JJ, et al. An adult presentation consistent with PIMS-TS. Lancet Rheumatol 2020;2:e520–1.
Flower L, Gale A, Elfar E, et al. O01 Adult onset PIMS-TS with secondary haemophagocytic lymphistiocytosis: into the eye of the cytokine storm. Rheumatol Adv Pract 2020;4.
Felsenstein S, Willis E, Lythgoe H, et al. Presentation, treatment response and short-term outcomes in paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS).J Clin Med 2020;9:3293.
Ellul MA, Benjamin L, Singh B, et al. Neurological associations of COVID-19. Lancet Neurol 2020;19:767–83.
Kabeerdoss J, Pilania RK, Karkhele R, et al. Severe COVID-19, Multisystem inflammatory syndrome in children, and Kawasaki disease: immunological mechanisms, clinical manifestations and management. Rheumatol Int 2021;41:19–32.
Jiang L, Tang K, Levin M, et al. COVID-19 and multisystem inflammatory syndrome in children and adolescents. Lancet Infect Dis 2020;20:e276–88.
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