Quinoline derivative and their pharmacological & medicinal potential

https://doi.org/10.53730/ijhs.v6nS3.5918

Authors

  • Preeti Mishra Raja Balwant Singh Engineering Technical campus, Faculty of Pharmacy Bichpuri, Agra
  • Avinash Kumar M.pharma scholar Department of Pharmacy, MJP Rohilkhand University Bareilly
  • Umesh Chand Sharma Raja Balwant Singh Engineering Technical campus, Faculty of Pharmacy Bichpuri, Agra
  • Ankit Saxena M. pharma scholar, Department of Pharmacy, MJP Rohilkhand University Bareilly
  • A. Elphine Prabahar Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad
  • Sushmita Gupta Department of Applied Chemistry, MJP Rohilkhand University, Bareilly
  • Amit Kumar Verma Faculty, Deptartment of pharmacy MJP Rohilkhand University Bareilly

Keywords:

quinolines, heterocyclic, anti-malarial, electrophile, chloroquine, amodiaquine

Abstract

The review article titled as “Quinolines” is basically designed with the aim of approaching the precious properties that the compound is entitled to possess. It is a heterocyclic compound possessing varied form of biological as well as pharmacological activity. This article basically focusses on the characteristics possessed by the compound of Quinoline. It tends to decipher a useful amount of information regarding the biological properties of the compound and its utilization in the development of various medications. The information provided in this article can be proved as a useful instrument for the various research scholars who are focusing their target of research with respect to Quinolines .It provides all the general information the quinolines and also throw light on the numerous therapeutic properties being possessed by the compound, that plays a prominent role in the treatment of various ailments.

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References

Marella A, Tanwar, O.P, Saha R, Ali M.A, Srivastava S, Akhter M, Shaquiquzzaman M, Alam M.M, ”Quinoline: A versatile heterocyclic”, Saudi Pharmaceutical Journal,(2013):21:1-12.

Mondal S,”Heterocyclic Chemisry Quinoline, Isoquinoline and Indole”, through https://www.researchgate.net/publication/325080072

Heeb, S, Fletcher M.P, Chhabra S.R, Diggle SP, Williams P & Camara M,” Quinolones: from antibiotics to autoinducers”, Published by Blackwell Publishing Ltd. All rights reserved, Rev 35 (2011) 247–274.

Correia S, Poeta P, Hebraud M, Capelo J.L and Igrejas G,” Mechanisms of quinolone action and resistance: where do we stand?”, Journal Of Medical Microbiology, 2017;66:551–559.

Chandrakanth B, Sastry V.G, Ramana H,” Synthesis And Biological Evaluation Of Novel Quinoline Compounds”, World Journal Of Pharmacy And Pharmaceutical Sciences, Volume 4, Issue 11, 1092-1101, through www.wjpps.com

Yamajala B.R.D. Rajesh,”Quinoline Heterocycles – Biological Activity”, November 19th 2018, through https://www.intechopen.com/chapters/64434

echnical Report Series. Geneva: World Health Organization; 2000. WHO Expert Committee on Malaria. 20th Report.

Snow RW, Guerra CA, Noor AM, Myint HY, Hay SI. The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature. 2005;434:214–7. [PMC free article] [PubMed]

Bathurst I, Hentschel C. Medicines for Malaria Venture: Sustaining antimalarial drug development. Trends Parasitology. 2006;22:301–7. [PubMed]

Gelb MG. Drug discovery for malaria: A very challenging and timely endeavor. Curr Opin Chem Biol. 2007;11:440–5. [PMC free article] [PubMed]

Rosenthal PJ. Antimalarial drug discovery: Old and new approaches. J Exp Biol. 2003;206:3735–44. [PubMed]

Robert A, Benoit-Vical F, Dechy-Cabaret O, Meunier B. From classical antimalarial drugs to new compounds based on the mechanism of action of artemisinin. Pure Appl Chem. 2001;73:1173–88.

Coslédan F, Fraisse L, Pellet A, Guillou F, Mordmüller B, Kremsner PG, et al. Selection of a trioxaquine as an antimalarial drug candidate. Proc Natl Acad Sci U S A. 2008;105:17579–84. [PMC free article] [PubMed]

Chen M, Theander TG, Christensen BS, Hviid L, Zhai L, Kharazmi A. Licochalcone A, a new antimalarial agent, inhibits in vitro growth of the human malaria parasite Plasmodium falciparum and protects mice from P.yoelii infection. Antimicrob Agents Chemothe. 1994;38:1470–5. [PMC free article] [PubMed]

Charris JE, Domínguez JN, Gamboa N, Rodrigues JR, Angel JE. Synthesis and antimalarial activity of E-2-quinolinylbenzocycloalcanones. Eur J Med Chem. 2005;40:875–81. [PubMed]

Domínguez JN, Charris JE, Lobo G, Gamboa-Domínguez N, Moreno MM, Riggione F, et al. Synthesis of quinolinyl chalcones and evaluation of their antimalarial activity. Eur J Med Chem. 2001;36:555–60.

Charris JE, Lobo GM, Camacho J, Ferrer R, Barazarte A, Domínguez JN, et al. Synthesis and Antimalarial Activity of (E) 2-(2’-Chloro-3’- Quinolinylmethyl idene)-5,7-Dimethoxyindanones. Lett Drug Des Discovery. 2007;4:49–54.

Liu M, Wilairat P, Go M-L. Antimalarial Alkoxylated and Hydroxylated Chalones: Structure—Activity Relationship Analysis. J Med Chem. 2001;44:4443–52.

Davis TM, Hung TY, Sim IK, Karunajeewa HA, Ilett KF. Piperaquine: A Resurgent Antimalarial Drug. Drugs. 2005;65:75–87.

Ayad F, Tilley L, Deady LW. Synthesis, antimalarial activity and inhibition of haem detoxification of novel bisquinolines. Bioorg Med Chem. 2001;11:2075–7.

Published

12-04-2022

How to Cite

Mishra, P., Kumar, A., Sharma, U. C., Saxena, A., Prabahar, A. E., Gupta, S., & Verma, A. K. (2022). Quinoline derivative and their pharmacological & medicinal potential. International Journal of Health Sciences, 6(S3), 2016–2040. https://doi.org/10.53730/ijhs.v6nS3.5918

Issue

Section

Peer Review Articles