Rosacea symptoms significantly decrease after skin barrier improvement
Keywords:
rosacea, clinical grading, perspective pilot studyAbstract
Rosacea is a common chronic inflammatory skin disease, characterised by wavy course – exacerbation alternates with remission. Currently rosacea is not completely curable, but using appropriate pharmacological treatment, medical devices, appropriate daily skin care routine and educating patients, is possible to control a rosacea activity. This study aims on testing whether there is skin barrier improvement leads to associated rosacea symptoms decrease after the application of the products developed on natural emollient emulsion base with active ingredients of natural origin without the use of traditional preservatives and preservatives of natural origin with irritating potential. This was a prospective, single-centre, placebo-controlled, double-blind randomised pilot study. The enrolled participants were randomised to receive one of four interventions. The testing was performed by clinical grading, assessment of facial skin condition and determination of qualitative parameters with skin diagnostic device. The results show reduction in redness and red spots, which indicates the blood vessel-strengthening and anti-inflammatory properties of the product ingredients. The decrease of porphyrins was observed in all participant groups. The decrease of porphyrins was observed in all participant groups of the study, which is explained by the high quality of the product emollient base developed with plant oils.
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