Circle fitting of boundaries of microarray spots
Keywords:
Circle fitting boundaries, microarray spots, Nearest Approximate Circle (NAC)Abstract
A new circle fitting algorithm is presented that generates the best circle to approximate the boundary of a given microarray spot. Here, the best approximation means, the total differential area between the circumference of the circle and the boundary of the spot is kept minimum. The center and the radius of the circle are determined to satisfy this condition. The differential area is used as a quantitative metric to represent the boundary quality of the corresponding microarray spot.
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Farouk RM, SayedElahl MA. (2015). “Robust cDNA microarray image segmentation and analysis technique based on Hough circle transform,” Human Frontier Science Program, HFSP journal, part.1, ISSN:1955-2068,Vol.9, Issue.7, 2015. pp. 1-13.
R. M. Farouk and M. A. SayedElahl, Microarray spot segmentation algorithm based on integro-differential operator, Egyptian Informatics Journal, https://doi.org/10.1016/j.eij.2019.04.001.
R. Karim, M. Khaliluzzaman and S. Mahmud, "A review of image analysis techniques for gene spot identification in cDNA Microarray images," The 2nd International Conference on Next Generation Information Technology, 2011, pp. 36-41.
Giannakeas, Nikolaos & Fotiadis, Dimitrios. (2009), “Image processing and machine learning techniques for the segmentation of cDNA microarray images,” Handbook of Research on Advanced Techniques in Diagnostic Imaging and Biomedical Applications. 294-306. 10.4018/978-1-60566-314-2.ch019.
V. Uslan and İ. Ö. Bucak, "Clustering-based spot segmentation of cDNA microarray images," 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology, 2010, pp. 1828-1831, doi: 10.1109/IEMBS.2010.5626430.
D. Maroulis and E. Zacharia, "Microarray image segmentation using spot morphological model," 2009 9th International Conference on Information Technology and Applications in Biomedicine, 2009, pp. 1-4, doi: 10.1109/ITAB.2009.5394330.
H. Yijun and W. Guirong, "Segmentation of cDNA Microarray Spots Using K-means Clustering Algorithm and Mathematical Morphology," 2009 WASE International Conference on Information Engineering, 2009, pp. 110-113, doi: 10.1109/ICIE.2009.17.
P. Ye and G. Weng, "Microarray Image Segmentation Using Region Growing Algorithm and Mathematical Morphology," 2009 Fifth International Conference on Information Assurance and Security, 2009, pp. 373-376, doi: 10.1109/IAS.2009.188.
J. Ho and W. Hwang, "Segmenting Microarray Image Spots using an Active Contour Approach," 2007 IEEE International Conference on Image Processing, 2007, pp. VI - 273-VI - 276, doi: 10.1109/ICIP.2007.4379574.
https://www.mathworks.com/help/matlab/ref/fminsearch.html.
https://www.mathworks.com/matlabcentral/answers/87111-how-can-i-draw-a-filled-circle.
H.K Yuen, J. Princen, J. Illingworth, and J. Kittler. "Comparative study of Hough transform methods for circle finding." Image and Vision Computing. Volume 8, Number 1, 1990, pp. 71–77. https://www.mathworks.com/help/images/ref/imfindcircles.html
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