Polymorphic light eruption
Clinico epidemiological study and histopathological correlation
Keywords:
PLE, sun allergy, clinico-epidemiology, histopathologyAbstract
Introduction: Polymorphic light eruption (PLE) is the most common photodermatoses encountered in clinical practice. It is an idiopathic acquired disorder in which a delayed response to Ultraviolet radiation occurs in the form of skin eruptions consisting of papules, vesicles or plaques over the sun exposed and rarely on partially covered areas, distribution is generally symmetrical. Diagnosis is clinical and histo-pathological features vary according to age of lesions sampled. Objective: To study clinical pattern of Polymorphic Light Eruption and Histo-Pathological Correlation Methods: The present study is a hospital based observational study, conducted over a period of one year. A total of 70 cases including male and female patients presenting with history of photosensitivity or with clinical manifestations related to photosensitivity were enrolled. All patients underwent clinical and systemic examination followed by routine and histo-pathological investigations. The findings were recorded in proforma for analysis and interpretation of data. Follow-up was done to know the prognosis of the patients. Results: The study shows that females are more affected than males with a ratio of 1:2.33 and the maximum incidence in the age group of 11-20 years and minimum in the age group of 51-60 years.
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Verma K, Rokde R, Singh U. A clinic epidemiological and histo-pathological study of polymorphic light eruptions in malwa region. Indian J Clin Exp Dermatol 2019;5:24-9.
Wadhwani AR, Sharma VK, Ramam M, Khaitan BK. A clinical study of the spectrum of photodermatoses in dark-skinned populations. ClinExp Dermatol 2013;38:823–9.
Chacko E, Vellaisamy SG, Gopalan K, Nanjappachetty G. A clinic-epidemilogical study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India. Int J Res Dermatol 2017;3:113-119.
Dogra S, Narang T.Emerging atypical and unusual presentationsof dermatophytosis in India. Clin Dermatol Rev 2017;1:S12-8.
Agarwal SB, Godse K, Patil S, Nadkarni N. Knowledge and attitude of general population toward effects of sun exposure and use of sunscreens. Indian J Dermatol 2018;63:285-91.
U. Mastalier and H. Keri, “Clinical, Laboratory, PhotoTest and Phototherapy Findings in Polymorphic Light Eruption: A
AlJasser MI, Lui H, Ball NJ, Kalia S. Persistent polymorphous light eruption after ultraviolet A1 phototherapy. Photodermatol Photoimmunol Photomed 2013;29:52-4.
Baliah K, Maduravasagam K, Radhakrishnan L, Jambulingam J. A prospective observational study on clinico - pathological correlation in polymorphous light eruption. IOSR J Dent Med Sci (IOSR-JDMS) 2016;15(10):01-7.
Elmets CA, Cala CM, Xu H. Photoimmunology. Dermatol Clin 2014;32:277–90.
Singh M, Sharma E. Novel and secure trend for photo protection-A Hallmark of plant metabolites as UV filters. Int J Rec Sci Res 2014;5:322-5.
Gruber‑Wackernagel A, Byrne SN, Wolf P. Polymorphous light eruption. Clinic aspects and pathogenesis. Dermatol Clin2014;32:315–34.
Singh S, Singh A, Mallick S, Arava S, Ramam M. Lichenoid pseudovesicular papular eruption on nose: A papular facial dermatosis probably related to actinic lichen nitidusor micropapular polymorphous light eruption. Indian J Dermatol Venereol Leprol 2019; 85:597-604.
Ibbotson S, Dawe R. Cutaneous Photosensitivity Diseases. In: Griffiths CEM, Barker J, Bleiker T, Chalmers R, Creamer D, editors. In Rook’s Textbook of Dermatology. 9th ed. John Wiley & Sons; 2016.p. 127.1‑127.35.
Pathania V, Shankar P, Shelley D, Baveja S, Sinha A. A case of Hansen’s disease masquerading as polymorphous light eruption. J Mar Med Soc 2019;21:196-8.
Prasad PV, Kaviarasan K, Sidhu U.A clinic-pathological study of poly morphous light eruption. J Cosmet Dermatol Sci Appl 2012;2:219-23.
Retrospective Study of 133 Patients,” Eur J Dermatol 8; 8;1998:554-559.
Sharma D, Dhillon K S. Polymorphic light eruption: A clinicoepidemiological study. Paripex- Indian J Res 2017;6(4): 661-663.
Kerr HA, Lim HW. Photodermatoses in African Americans: a retrospective analysis of 135 patients over a 7-year period. J Am Acad Dermatol 2007;57:638-643.
Lal BM, Devi AS, Suhasini K. The study of clinical variations and histopathological findings in polymorphous light eruption. J Evid Based Med Healthc 2016;3:2899-904.
Rodríguez-Pazos L, Gómez-Bernal S, Rodrígue-Granados MT, Toribio J. Photodistributed erythema multiforme. Actas Dermo-Sifiliográficas 2013;104:645-53.
Van de Pas LB, Kelly DA, Seed PT et al. Ultraviolet radiation induced erythema and suppression of contact hypersensitivity responses in patients with polymorphic light eruption. J. Invest Dermatol. 2004; 122: 295-9.
Harber and Bickers. Photosensitivity disease. Philadelphia, Saunders. 1981; 109: 170-182.
Dermatologic Disease Database: Polymorphous light eruption: http:// www.aocd.org/ skin/ dermatologic-disease/ polymorphous-light eruption.htm. on 21st Jan. 06.
Reinhard et al. Clinical and therapeutic aspects of polymorphous light eruption. Dept of Dermatology, University Hospital, Zurich, Switzerland. Dermatology 2003; 207: 93-95.
Kontus AP et al. Polymorphous light eruption in African Americans: Pinpoint papular variant. Photodermatol Photoimmunol Photomed. 2002 Dec; 18(6): 303-6.
Abeyama K et al. A role for NF kappa B-independent gene transactivation in sunburn. J Clin Invest. 2000; 105: 1751.
Main RA. Polymorphous light eruption. Practitioner. 1966; 196: 654-60.
Bounstra HE et al. Polymorphous light eruption: A clinical, photobiologic and follow-up study of 110 patients. J Am Acad Dermatol. 2000 Feb; 42(2 pt 1): 199-207.
Orr PH, Birt AR. Hereditary polymorphic light eruption in Canadian unit. Int J Dermatol. 1984; 23(7): 472-5.
Millard TP et al. The heritability of polymorphic light eruption. J Invest. Dermatol. 2000 Sept. 115 (3): 467-70.
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