A review on pharmacological activities of Mukia maderaspatana
Keywords:
cucurbits, herbal drug, mukia maderaspatana, musumusukkai, pharmacological activity, phytochemicalsAbstract
Cucurbits are consumable crops, belonging to the family of Cucurbitaceae. They are widely distributed in the regions of tropical and sub-tropical region. These tendril climbers are grown in village surrounding. The plant has been grown from olden days for its medicinal value. It is used as herbal drug for cough and cold. All parts of plant such as leaf, stem, root, fruit and seeds are used in historical system of medicine. Cucurbits are naturally trailing plant. Edible food such as watermelon and cucumber are found in cucurbit family. Plants belonging to cucurbits family are higher in nutritional value. Mukia maderaspatana belongs to Cucurbitaceae genus. It is (called as “musumusukkai” in tamil). It is also known as Cucumis maderaspatana. Mukia maderaspatana has pharmacological activities such as aperient, diuretic, stomachic, antipyretic, anti-flatulent, anti-asthmatic, antitussive, antihistaminic, antibronchitic, hypolipidemic, hepatoprotective, hypoglycaemic, antiulcer. Phytochemical screening shows the presence of glycosides, flavonoids, phenols, alkaloids, saponin, carbohydrate and steroid in ethanol and methanol extraction. In this article we discuss on pharmacological activities of Mukia maderaspatana.
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References
Agata Rolnik MSc., Beata Olas PhD. (2020). Vegetables from the Cucurbitaceae family and their products: Positive effect on human health. Nutrition. 78.
Amaq Fadholly, Arif N. M. Ansori, Teguh H. Sucipto. (2020). An Overview of Naringin : Potential Anticancer compound of Citrus Fruits. Research Journal of Pharmacy and Technology. 13(11) : 5613-5619.
Asha K Rajan, Narayanan N, Valentina P, Maheshwaran A, Senthilnathan B. (2016). A Recapitulation on the Medicinal Benediction of Mukia maderaspatana. Inventi Rapid. Planta Activa Vol. Issue 4.
Bhavika D, Satone, Atul A. Deshmukh, Vaishali R. Undale. (2020). Preclinical Evaluation of Antihypertensive Activity of Combination of Herbs Extract in Wistar Rats. Research Journal of Pharmacy and Technology. 13(5): 2069-2075.
Boobalan Raja, Kuppusamy Kaviarasan, Mangalam Muthu Arjunan, Kodukkur Viswanathan Pugalendi. (2007). Effect of Melothira maderaspatana Leaf-Tea Consumption on Blood Pressure, Lipid Profile, Anthropometry, Fibrinogen, Bilirubin, and Albumin Levels in Patients with Hypertension. The Journal of alternative and complementary medicine. 13(3): 349-354.
Chinnadurai Verramani, Balakrishnan Aristatile, Ganesan Pushpavali, kodukkur Viswanathan Pugalendi. (2010). Effects of Melothira maderaspatana leaf extract on antioxidant status in sham-operated and uninephrectomized DOCA-salt hypertensive rats. Saudi Journal of Biological Sciences. 18(1): 99-105.
Deepali Pandey, Shailendra Pandey, Hemalatha S. (2010). Hypolipidemic activity of aqueous extract of Melothira maderaspatana. Pharmacologyonline. 3: 76-83.
Dr. Julius.A, Ramachandran Vedasendiyar, Dr. Archana Devakannan, Sujatha Rajaraman, Balamurugan Rangasamy, Saravanan V. (2017). Effect of Hesperidin for its Anti-Proliferative Activity on Liver Cancer and Cardio Vascular Diseases. Research Journal of Pharmacy and Technology. 10(1): 307-308.
Gomathy G, Venkatesan D, Palani S. (2014). Gastroprotective potentials of the ethanolic extract of Mukia maderaspatana against indomethacin-induced gastric ulcer in rats. Natural Product Research. 29(22): 2107-2111.
Gomathy G,Vijay T, Sarumathy K, Gunasekaran S, Palani S. (2012). Phytochemical screening and GC-MS analysis of Mukia maderaspatana (L.) leaves. Journal of Pharmaceutical Science. 2(12): 104-106.
Habibur Rahman, Chinna Eswaraiah M, Anoosha T , Nagaveni K, Manjula K. (2013). Evaluation for CNS Activities of Hexane Extract of Citrullus lanatus Seeds. Research Journal of Pharmacy and Technology. 6(8) : 878-884.
Indhumathi paramasivam, Simran sinsinwar, Meenakshi Sundaram Muthuraman. (2017). Phytopharmacological Properties of Melothira Maderaspatana : A review. Asian journal of Pharmaceutical and clinical research. 10(8): 34-36.
Jamuna S, Karthika K, Paulsamy S. (2015). Phytochemical and Pharmacological properties of certain medicinally important species of Cucurbitaceae family- a review. Journal of Research In Biology. 5(6): 1835-1849.
Katolkar P.P, Nimbekar TP, Wanjari B.E , Nema M.V , Dongarwar. (2012). In-vitro antimitotic activity and antiproliferative activity of different extract of Belanites aegyptiaca . Research Journal of Pharmacy and Technology. 5(4: 474-477.
Kavitha M, Dr. Srinivasan P.T, Lakshmi Priya S, Jayakumar L.V. (2013). Evaluation of Nutrient Composition and antibacterial Potential of Leaf and stem of Mukia maderaspatana I. International Journal of Pharmaceutical research & Allied Sciences. 2(3): 68-76.
Kavitha M, Srinivasan.P.T, Renuga G and Jayakumar L.V. (2014). Evaluation of Antimitotic activity of Mukia maderaspatana L. Leaf Extract in Allium cepa Root Model. International Journal of Pharmacy Research and Technology. 4(1) : 65-68.
Lavanya M, Anusha G, Seshu Lavanya R, Mary Prasanna Kumari B, Anand Kumar P, Parvathi M and Sandeep D. (2013). In-vitro comparative Study of Anthelmintic Activity of Mukia maderaspatana and Sida cordata. International journal of Pharmaceutical and chemical sciences. 2(2). 1020-1024.
Mallikadevi T, PaulsamyS, KarthikaK, Jamuna S. (2012). In-vitro and in-vivo anti-inflammatory activity of whole plant methanolic extract of Mukia maderaspatana (L.) M. ROEM. (CUCURBITACEAE). International Journal of pharmacy and Pharmaceutical Sciences. 4(5): 435-439.
Manoharan A, Manjula M, Mubarak H, Chitti C.V, Babu. (2015). Hypolipidaemic activity of the siddha medicinal plants, International Journal of Pharmacognosy. 2(4): 145-154.
Moumita Banerjee, Thankamani V. (2013). Antimicrobial activity of plant Mukia maderaspatana. International Journal of Pharmacy and Pharmaceutical Sciences. 5(4): 199-202.
Moyeenudin H.M, Vijayalakshmi S. (2019). The Antihypertensive Effect from Aqueous Extract of Oxalis corniculata by In Vitro Antihypertensive Activity Assay. Research Journal of Pharmacy and Technology. 12(6): 2981-2986.
Petrus A J A. (2013). Ethnobotanical and pharmacological profile with propagation strategies of Mukia maderaspatana (L.) M. Roem.- A concise overview. Indian journal of Natural Products and Resources. 4(1): 9-26.
Rahman A.H.M.M, Anisuzzaman M, Alam M.Z, Islam A.K.M.R, Zaman A.T.M.N. (2006). Taxonomic Studies of the Cucurbits grown in the Northern Parts of Bangladesh. Research Journal of Agriculture and Biological Sciences. 2(6): 299-302.
Raja MJ, Jagadeswaran A. (2021). Exploration of Mukia maderaspatana as promising topical herbal preparation for cutaneous warts in cattle. The Pharma Innovation Journal. 10(5): 653-659.
Ramachandran Vadivelan, Sanagai Palaniswami Dhanabal, Ashish Wadhawani, Kannan Elango. (2012). α-Glucosidase and α-Amylase inhibitory activities of Mukia maderaspatana (L) Roem. Journal of Intercultural Ethnopharmacology. 1(2): 97-100.
Rekha Rajendran, Hemachander R, Ezhilarasan T,Keerthana C, aroja DL, Saichand KV, Mohamed Gasim Abdullah. (2010). Phytochemical Analysis and In-Vitro Antioxidant Activity of Mimosa pudica Lin., Leaves. Research Journal of Pharmacy and Technology. 3(2). 551-555.
Saravanan V.S, Manokaran. (2012). Anti-anaemic activity of some plants in Cucurbitaceae on phenylhydrazine-induced anaemic rats. Thai journal of Pharmaceutical sciences. 36; 150-154.
Sengottuvel T, Sanish Devan V. (2020). In vitro Antidiabetic activity of hydroalcoholic leaf extract of Cucumis melo var agrestis (Cucurbitaceae). Research Journal of Pharmacy and Technology. 13(12): 5851-5854.
Suganthi A, Mary Josephine R. (2017). In-vitro cytoxicity of M.Maderaspatana (Linn) Cogn. Fruit Methanol Extract against MCF 7 Human Breast Cancer Cell Line and Quantification of Beta Caartenoid in HPLC. American Journal of Pharmtech research. 7(6): 84-93.
Sugashini Settu, Sathiavelu Arunachalam. (2019). Comparison of phytochemical analysis and In-vitro pharmacological activities of most commonly available medicinal plants belonging to the Cucurbitaceae family. Research Journal of Pharmacy and Technology. 12(4), 1541-1546.
Sujeethasai K. (2020). Medicinal uses and Pharmacological Activities of Mukia maderaspatana (Linn.)- A review. International Journal of Recent Scientific Research. 11(4): 38292-38296.
Sundarrajan T, Vijey Aanandhi M. (2018). Hypolipidemic activity of Alternanthera ficoidea Linn in Triton wr-1339 induced hyperlipidemic rats. Research Journal of Pharmacy and Technology. 11(2): 687-689.
Udaya Prakash N.K, Bhuvaneswari S, Sripriya N, Prameela,L, Bhagya R, Raddhika B, Balamurugan A, Arokiyaraj S. (2014). Antioxidant activity of common plants of northern Tamilnadu, India. International journal of Pharmacy and Pharmaceutical Sciences. 6(4): 128-132.
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