To compare the effects of adding buprenorphine vs dexmedetomidine in patients undergoing forearm surgeries under supraclavicular brachial plexus block

https://doi.org/10.53730/ijhs.v6nS1.6879

Authors

  • Vangali Sreelakshmi Associate Professor, Department of Anaesthesiology, Santhiram Medical College and General Hospital, Nandyal, Andhra Pradesh
  • Niyaz PV Postgraduate, Department of Anaesthesiology, Santhiram Medical College and General Hospital, Nandyal, Andhra Pradesh
  • Talikota Nagaraju Associate Professor, Department of Anaesthesiology, Santhiram Medical College and General Hospital, Nandyal, Andhra Pradesh
  • Anusha Aluri Assistant Professor, Department of Anaesthesiology, Santhiram Medical College and General Hospital, Nandyal, Andhra Pradesh

Keywords:

2% Lignocaine with adrenaline, Dexmedetomidine, Buprenorphine, Supraclavicular brachial plexus block

Abstract

Background: Supraclavicular brachial plexus block is the most commonly employed regional anaesthesia technique for upperlimb surgeries below elbow joint. Many drugs are used as adjuvants to local anaesthetics in order to extend and improve the quality of intraoperative and postoperative anaesthesia. We conducted a study to compare the effects of adding Buprenorphine vs Dexmedetomidine to intermediate-acting local anaesthetic 2% lignocaine with adrenaline in supraclavicular brachial plexus block. Aims and objectives: To compare the effects of adding Buprenorphine vs Dexmedetomidine to 2% lignocaine with adrenaline (1 in 200000) in patients undergoing forearm surgeries under supraclavicular brachial plexus block in terms of onset and duration of sensory and motor blockade, as well as the duration of postoperative analgesia. Materials and methods: 80 ASA Grade 1 & 2 patients aged between 18 and 60 years, of both sexes, undergoing forearm surgeries under supraclavicular brachial plexus block were divided into 2 groups of 40 each. Group A received 7mg/kg of 2% lignocaine with adrenaline + Buprenorphine 3µg/kg. Group B received 7mg/kg of 2% lignocaine with adrenaline (1 in 200000)+ Dexmedetomidine(1µg/kg).

Downloads

Download data is not yet available.

References

Damien BM, Colin JL, McCartney, Vincet WS. Novel analgesic adjuvants for brachial plexus block. A systemic review. A&A. 2000:90:1122–28.

Bazin JE, Massoni C, Bruelle P, Fenies V, Groslier D, Schoeffler P. The addition of opioids to local anaesthetics in brachial plexus block: the comparative effects of morphine, buprenorphine and sufentanil. Anaesthesia. 1997; 52:858–62.

Candido KD, Franco CD, Khan MA, Winnie AP, Raja DS. Buprenorphine added to the local anesthetic for brachial plexus block to provide postoperative analgesia in outpatients. Reg Anesth Pain Med. 2001;26:352–6.

Candido KD, Winnie AP, Ghaleb AH, Fattouh MW, Franco CD. Buprenorphine added to the local anesthetic for axillary brachial plexus block prolongs postoperative analgesia. Reg Anesth Pain Med. 2002; 27:162–7.

Behr A, Freo U, Ori C, Westermann B, Alemanno F. Buprenorphine added to levobupivacaine enhances postoperative analgesia of middle interscalene brachial plexus block. J Anesth. 2012;26(5):746-751.

Patil S, Debata D, Doshi C, Vyas V, Sinha S. Effect of buprenorphine as an adjunct with plain local anesthetic solution in supraclavicular brachial plexus block on quality and duration of postoperative analgesia. Journal of anaesthesiology, clinical pharmacology. 2015 Oct;31(4):496.

Esmaoglu A, Yegenoglu F, Akin A, Turk CY. Dexmedetomidine added to levobupivacaine prolongs axillary brachial plexus block. Anesth Analg.2010; 111:1548–51.

Swami SS, Keniya VM, Ladi SD, Rao R. Comparison of dexmedetomidine and clonidine as an adjuvant to local anaesthesia in supraclavicular brachial plexus block: A randomised double-blind prospective study. Indian J Anaesth. 2012;56:243–9.

Kaur H, Singh G, Rani S, Gupta KK, Kumar M, Rajpal AS, Aggarwal S.Effect of dexmedetomidine as an adjuvant to levobupivacaine in supraclavicular brachial plexus block J Anaesthesiol Clin Pharmacol. 2015 Jul-Sep;31(3):333-8.

Brummett CM, Norat MA, Palmisano JM, Lydic R. Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat. Anesthesiology 2008;109:p 502-11.

Sarkar DJ, Khurana G, Chaudhary A, Sharma JP. A comparative study on the effects of adding fentanyl and buprenorphine to local anaesthetics in brachial plexus block. J Clin Diagn Res. 2010; 4:3337–43.

Damien B, Murhy CJ, Cartney VW. Novel analgesic adjuvants for brachial plexus block: A systemic review. Anesth Analg. 2000;90:1122-8.

Palsule VS, Shah AP, Kanzariya HH. Dexmedetomidine in supraclavicular block: Effects on quality of block and analgesia. Indian Journal of Pain. 2017 Jan 1;31(1):28.

Franco CD, Vieira ZE. 1,001 subclavian perivascular brachial plexus blocks: success with a nerve stimulator. Regional Anesthesia & Pain Medicine. 2000 Jan 1;25(1):41- 6.

Dogru K, Duygulu F, Yildiz K, Kotanoglu MS, Madenoglu H, Boyaci A. Haemodynamic and blockade effects of high/low epinephrine doses during axillary brachial plexus blockade with lidocaine 1.5%: A randomized, double-blinded study. Reg Anesth Pain Med. 2003;28:401–05.

Singam A, Chaudhari A, Nagrale M. Buprenorphine as an adjuvant in supraclavicular brachial plexus block. Int J Biomed Adv Res. 2012;03:571-5.

Sanghvi KS, Shah VA, Patel KD. Comparative study of bupivacaine alone and bupivacaine along with buprenorphine in axillary brachial plexus block: A prospective, randomized, single blind study Int J Basic Clin Pharmacol. 2013;02:640–4.

Dixit R, Chakole V, Tadwalkar GV. Effect of buprenorphine on post operative analgesia in supraclavicular brachial plexus block using peripheral nerve locator. Journal of Evolution of Medical and Dental Sciences. 2013 Jan 14;2(2):114-9.

Jadon A, Panigrahi MR, Parida SS, Chakraborty S, Agrawal PS, Panda A. Buprenorphine improves the efficacy of bupivacaine in nerve plexus block: A double blind randomized evaluation in subclavian perivascular brachial block. J Anaesth Clin Pharmacol. 2009 Apr 1;25(2):207-10.

Jain N, Khare A, Khandelwal S, Mathur P, Singh M, Mathur V. Buprenorphine as an adjuvant to 0.5% ropivacaine for ultrasound-guided supraclavicular brachial plexus block: A randomized, double-blind, prospective study. Indian J Pain 2017;31:112-8.

Thakur A, Singh J ,Kumar S, Rana S,Sood P,Verma . Efficacy of dexmedetomidine in two different doses as an adjuvant to lignocaine in patients scheduled for surgeries under axillary block. Journal of clinical and diagnostic research :JCDR.2017 Apr;11(4):UC16.

Published

02-05-2022

How to Cite

Sreelakshmi, V., Niyaz, P. V., Nagaraju, T., & Aluri, A. (2022). To compare the effects of adding buprenorphine vs dexmedetomidine in patients undergoing forearm surgeries under supraclavicular brachial plexus block. International Journal of Health Sciences, 6(S1), 8488–8498. https://doi.org/10.53730/ijhs.v6nS1.6879

Issue

Section

Peer Review Articles