Study of medication adherence to insulin therapy in type II diabetic patients
Keywords:
medication adherence, cross-sectional, comorbidity, hypertensionAbstract
Non adherence is the major and unrecognized risk factor for the uncontrollable reduction for blood sugar.Type-2 diabetes mellitus and its complication are becoming more prevalent in India. Evidence abound that the most important predictor of reduction of morbidity and mortality due to diabetes complication is the level of glycemic control achieved through medication adherence.The purpose of this study was to evaluate the Medication adherence of patients with T2DM who received Insulin therapy and to identify other factors that can affect the medication adherence. A cross-sectional, observational study which was carried out for 6 months on Paul Moses Hospital in Chennai. A total of 100 patients with type 2 DM on insulin therapy for atleast 1 year were recruited. Blood Glucose level and other details of comorbidity were noted. 84% of patients were administered Insulin subcutaneously. Most common comorbidity observed in the diabetic patients was hypertension. Medication Adherence was assessed using validated predefined questionnaire and adherence scores were calculated. The most common factors for non-adherence in male were too busy with their work (62.79%) and in female was inconvenience (62.79%). The p-value is < .05 reports that its significance incomparison of adherence and non-adherence.
Downloads
References
Ghane’i R, Golkar F. Foot care in depressed and non-depressed diabetic patients. Mod Care J. 2013;10(2):124–131. [Google Scholar]
Ramphal R. Endocronolgy and Methabolism. In: Fauci AS, Braunwald E, Kasper DL, editors. Harrison Principles of Internal Medicine. 17th ed. New York, NY: McGraw Hill Medical; 2008. pp. 949–956. [Google Scholar]
Grundy SM, Benjamin IJ, Burke GL, Chait A, Eckel RH, Howard BV, Mitch W, Smith SC Jr, Sowers JR: Diabetes and cardiovascular disease: a statement for health care professionals from the American Heart Association. Circulation 100:1134–1146, 1999 FREE Full TextGoogle Scholar
World Health Organization, diabetes mellitus fact sheet, number 238, 2002. [Accessed August 13, 2006].at http://www.who.int/diabetes .
American Diabetes Association. Implications of the United Kingdom Prospective Diabetes Study. Diabetes Care. 1999;22:27–31. [PubMed] [Google Scholar]
Roper NA, Bilous RW, Kelly WF, Unwin NC, Connolly VM. Excess mortality in a population with diabetes and the impact of material deprivation: longitudinal, population based study. BMJ 2001;322:1389–1393 [PMC free article] [PubMed] [Google Scholar]
Currie CJ, Gale EA, Poole CD. Estimation of primary care treatment costs and treatment efficacy for people with type 1 and type 2 diabetes in the United Kingdom from 1997 to 2007. Diabet Med 2010;27:938–948 [PubMed] [Google Scholar]
Manuel DG, Schultz SE. Health-related quality of life and health-adjusted life expectancy of people with diabetes in Ontario, Canada, 1996-1997. Diabetes Care 2004;27:407–414 [PubMed] [Google Scholar]
Nathan DM, Buse JB, Davidson MB, et al. American Diabetes Association. European Association for the Study of Diabetes Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2009;32:193–203 [PMC free article] [PubMed] [Google Scholar]
Karter AJ, Ackerson LM, Darbinian JA, et al. Self-monitoring of blood glucose levels and glycemic control: the Northern California Kaiser Permanente Diabetes Registry. Am J Med 2001;111:1–9 [PubMed] [Google Scholar]
AmericanDiabetesAssociation,“8.Pharmacologicapproachestoglycemictreatment:StandardsofMedicalCareinDiabetes—2018,”DiabetesCare,vol.41,Supplement1,pp.S73–S85,2018.
A. J. Garber, M. J. Abrahamson, J. I. Barzilay et al., “Consensusstatement by the American Association of Clinical Endocri-nologistsandAmericanCollegeofEndocrinologyonthecomprehensivetype2diabetesmanagementalgorithm –2018 executive summary,” Endocrine Practice, vol. 24, no. 1,pp.91–120,2018.
M.Khunti,M.L.Wolden,B.L.Thorsted,M.Andersen,and M. J. Davies, “Clinical inertia in people with type 2 diabetes:aretrospectivecohortstudyofmorethan80,000people,”Dia-betesCare,vol.36,no.11,pp.3411–3417,2013.
M.Peyrot,R.R.Rubin,T.Lauritzenetal.,“Resistancetoinsu-lin therapy among patients and providers: results of the cross-nationaldiabetesattitudes,wishes,andneeds(DAWN)study,”DiabetesCare,vol.28,no.11,pp.2673–2679,2005.
Ghane’i R, Golkar F. Foot care in depressed and non-depressed diabetic patients. Mod Care J. 2013;10(2):124–131. [Google Scholar]
Maslakpak M, Ahmadi F, Anoosheh M. Spiritual beliefs and quality of life: A qualitative research about diabetic adolescent girls’ perception. Koomesh. 2011;12(2):144–151. [Google Scholar]
Lerman I. Adherence to treatment: the key for avoiding long-term complications of diabetes. Arch Med Res. 2005;36(3):300–306 doi:10.1016/j.arcmed.2004.12.001 [PubMed] [CrossRef] [Google Scholar]
Gonzalez JS, McCarl LA. Cognitive behavioral therapy for adherence and depression (CBT-AD) in type 2 diabetes. J CognPsychother. 2010;24(4):329. doi:10.1891/0889-8391.24.4.329 [PMC free article] [PubMed] [CrossRef] [Google Scholar]
18.Hugtenburg JG, Timmers L, Elders PJ, Vervloet M, van Dijk L. Definitions, variants, and causes of nonadherence with medication: a challenge for tailored interventions. Patient preference and adherence. 2013;7:675–82.Article Google Scholar
Vrijens B, De Geest S, Hughes DA, Przemyslaw K, Demonceau J, Ruppar T, et al. A new taxonomy for describing and defining adherence to medications.Br J ClinPharmacol. 2012;73(5):691–705.Article Google Scholar
Garber MC, Nau DP, Erickson SR, Aikens JE, Lawrence JB. The concordance of self-report with other measures of medication adherence: a summary of the literature. Med Care. 2004;42(7):649–52.Article Google Scholar
Dolores SD, editor. Greenspan’s Basic and Clinical Endocrinology. 9th ed. Ch. 17New York: McGraw-Hill Medical; 2011.
Perry M. Early detection of Type 2 diabetes: The role of the community nurse. Br J Community Nurs 2001;6:176-9.
WHO. Adherence to Long Term Therapies, Time for Action. Geneva: World Health Organization; 2003. p. 221
Egede LE, Gebregziabher M, Echols C, Lynch CP. Longitudinal effects of medication nonadherence on glycemic control. Ann Pharmacother. 2014;48(5):562–570. [PubMed] [Google Scholar]
Baghianimoghadam, Mohammad H, Afkhami-Ardekani M. Effect of Education on Improvement of Quality of Life by SF-20 in Type 2 Diabetic Patients. MiddleEast Journal of Scientific Research. 2008;3(2):67-72.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
