Antidepressants exposure during gestation and their impact on the neurodevelopment and physical outcomes in the off spring
Keywords:
antidepressants, estation, neurodevelopment, physical outcomes, off springAbstract
This study is aimed to study the gestational exposure to antidepressants and their impact on the neurodevelopment and physical outcomes in the offspring. The objective of the study is to General and medical information, as well as estimations of the level of mental distress will be obtained by standardized questionnaires. To accesses the prevalence of antidepressant associated symptoms in new born Assessment of Neurodevelopment and physical outcomes of child by using standardized questionnaires namely Early Motor Questionnaire (EMQ) for age group of children from 1-6 years which is parent questionnaire were circulated to control (n-150) and case (n-150). Physical outcomes like congenital malformations, birth weight, seizures, hospitalization, preterm delivery, respiratory distress of children were collected from retrospective data maintained during gestational period and child birth which were collected from clinic. In pregnant women baseline risk of congenital malformations is about 3%, and of cardiovascular malformations, 1%. Rates of spontaneous abortion vary in general population between 15 and 20%. Pre-term births occur in approximately 13% of pregnancies, we found relation between exposure of prenatal antidepressants and occurrence of physical outcomes like low birth weight, miscarriages, hospitalization, preterm births, respiratory distress, seizures, gastrointestinal problems, improper.
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