The value of diffusion weighted MRI in evaluation of pancreatic lesions
Keywords:
DW MRI, ADC value, malignant pancreatic tumors, prognosis, pancreatic cancerAbstract
Pancreatic lesions are very common and the pancreatic cancer is one of the most fatal cancers. The aim of the study was to show the value of diffusion weighted MRI in evaluation of pancreatic lesions, especially pancreatic cancer and to correlate the results of DW MRI with that of pathology or tumor markers aiming to use DWI MRI as a reasonable alternative modality especially when contrast administration is contraindicated. The study included 30 patients performed in the radiology department, El-Hussein Hospital University as well as a private center. The age of the patients ranged from 27 to 76 years (mean =51.13). MR imaging was performed on high field system (1.5 Tesla) magnet units (Philips Acheiva) and siemens. The ADC value of malignant pancreatic tumors was significantly lower than that of the normal pancreas with mean values of 1.27±0.21×10-3 mm2/sec and 1.61±0.13×10-3 mm2/sec respectively. Sensitivity of DW MRI was 95.5%, specificity 75%, NPV 85.7 % and PPV 91.3%, while Sensitivity of contrast enhanced MRI was 95.5 %,specificity 62.5 %,NPV 83.3 % and PPV (positive predictive value) 87.5%.
Downloads
References
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, et al. Cancer statistics. CA Cancer J Clin, 2016; 58(2): 71–96.
Hänninen EL, Amthauer H, Nor Hosten N. Prospective Evaluation of Pancreatic Tumors: Accuracy of MR Imaging with MR Cholangiopancreatography and MRAngiography. Radiology 2015; 224: 34-41.
Robertson RL, Glasier CM. Diffusion-weighted imaging of the brain in infants and children. Pediatr Radiol, 2016; 37(8): 749–768.
Bruegel M, Holzapfel K, Gaa J, Woertler K, Waldt S, Kiefer B, et al. Characterization of focal liver lesions by ADC measurements using a respiratory triggered diffusion-weighted single-shot echoplanar MR imaging technique. Eur Radiol,2008; 18(3):477–485.
Matsuki M, Inada Y, Nakai G, Tatsugami F, Tanikake M, Narabayashi I, et al/. Diffusion-weighted MR imaging of pancreatic carcinoma. Abdom Imaging, 2015; 32 (4): 481–483.
Wen C, Jing S, Shi Y, Jian LU. Differentiation between pancreatic carcinoma and mass-forming chronic pancreatitis: Usefulness of high b value diffusion-weighted imaging. Journal of Digestive Diseases 2011; 12: 401–40.
Nikolaos Kartalis, Terri L. Lindholm, Peter Aspelin, Johan Permert, Nils Albiin. Diffusion-weighted magnetic resonanceimaging of pancreas tumours. Eur Radiol (2009) 19: 1981–1990.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
