Correlation between epilepsy risk factors and type of seizures in children
Keywords:
correlation, epilepsy, risk factors, seizuresAbstract
Epilepsy is uncommon on its own, and comorbidities are common: more than half of patients with epilepsy have one or more other medical disorders. Epilepsy has long been linked to psychiatric disorders (such as Extreme stress, extreme sadness, hyperactivity, and attention deficit), but more recently, epilepsy has been linked to somatic disorders (such as Disorders of the pancreas and its secretion of insulin, problems with tendons and joints, diseases that affect the stomach and chronic diseases related to the lung). A descriptive, Case-Control study was conducted. The research was carried out across Iraq's five Middle Euphrates Governorates, between the 1st of October 2021 and the 1st of May 2022. For the purpose of determining risk factors for epilepsy in children and to identify the relationship between the risk factors and parents socio-demographic data, clinical data and daily habits. The data was collected through the use of the questionnaire and data analysis by SPSS version 22. The findings indicate that the most important factors influencing the occurrence of epilepsy in children are as follows: (asphyxia, trauma during delivery, jaundice, febrile, encephalitis, meningitis, brain tumor, ADHD, and head trauma). as well as the occurrence of epilepsy is influenced by considerable sleep disruption.
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Abdulkareem, A. G. (2022). Epilepsy and Child History in Dr Jamal Ahmad Rashid Pediatric Teaching Hospital Sulaimani /Iraq. Kurdistan Journal of Applied Research, 6(2), 117–126. https://doi.org/10.24017/science.2021.2.11
Barker-Haliski, M., Sills, G. J., & White, H. S. (2014). What are the arguments for and against rational therapy for epilepsy? Advances in Experimental Medicine and Biology, 813, 295–308. https://doi.org/10.1007/978-94-17-8914-1_24
Berg, A. T., Jallon, P., & Preux, P. M. (2013). The epidemiology of seizure disorders in infancy and childhood: Definitions and classifications. In Handbook of Clinical Neurology (1st ed., Vol. 111). Elsevier B.V. https://doi.org/10.1016/B978-0-444-52891-9.00043-9
Camfield P, & Camfield C. (2015). Incidence, prevalence and aetiology of seizures. Epileptic Disord, 17(2), 117–123.
Chowdhury, R. N. (2014). Precipitating factor of seizure in epilepsy: experience in a tertiary care hospital. Europepmc. https://europepmc.org/article/med/24584374#impact
Fiest, K. M., Sauro, K. M., Wiebe, S., Patten, S. B., Dykeman, J., Pringsheim, T., & Lorenzetti, D. L. (2016). Prevalence and incidence of epilepsy A systematic review and meta-analysis of international studies.
Fisher, R. S., & Bonner, A. M. (2018). The Revised Definition and Classification of Epilepsy for Neurodiagnostic Technologists. Neurodiagnostic Journal, 58(1), 1–10. https://doi.org/10.1080/21646821.2018.1428455
Glozman, J. (2013). Developmental neuropsychology. In Developmental Neuropsychology. https://doi.org/10.4324/9780203081181
Goldberg, E. M., & Coulter, D. A. (2013). Mechanisms of epileptogenesis: A convergence on neural circuit dysfunction. Nature Reviews Neuroscience, 14(5), 337–349. https://doi.org/10.1038/nrn3482
Guo, D., Zeng, L., Brody, D. L., & Wong, M. (2013). Rapamycin Attenuates the Development of Posttraumatic Epilepsy in a Mouse Model of Traumatic Brain Injury. PLoS ONE, 8(5). https://doi.org/10.1371/journal.pone.0064078
Iacone, Y., Morais, T. P., David, F., Delicata, F., Sandle, J., Raffai, T., Parri, H. R., Weisser, J. J., Bundgaard, C., Klewe, I. V., Tamás, G., Thomsen, M. S., Crunelli, V., & Lőrincz, M. L. (2021). Systemic administration of ivabradine, a hyperpolarization-activated cyclic nucleotide-gated channel inhibitor, blocks spontaneous absence seizures. Epilepsia, 62(7), 1729–1743. https://doi.org/10.1111/epi.16926
Jebur, N. J., Jumaa, A. K., & Hussain, S. A. (2021). Knowledge, Awareness and Attitude of Pharmacy Students towards Epilepsy in Iraq. Medico Legal Update, 21(2), 1333–1343. https://doi.org/10.37506/mlu.v21i2.2877
Keezer, M. R., Sisodiya, S. M., & Sander, J. W. (2016). Comorbidities of epilepsy: Current concepts and future perspectives. The Lancet Neurology, 15(1), 106–115. https://doi.org/10.1016/S1474-4422(15)00225-2
Kumar, M., & Kalita, J. (2018). Seizures in tuberculous meningitis.pdf.
Löscher, W. (2011). Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs. Seizure, 20(5), 359–368. https://doi.org/10.1016/j.seizure.2011.01.003
Mishra, O. P., Upadhyay, A., Prasad, R., Upadhyay, S. K., & Piplani, S. K. (2017). Behavioral problems in Indian children with epilepsy. Indian Pediatrics, 54(2), 116–120. https://doi.org/10.1007/s13312-017-1012-7
Nimesh, S., Tomar, R., Kumar, M., Tyagi, N., & Shukla, P. K. (2019). A pharmacovigilance study of monitoring & focusing of adverse drug reactions induced by antiepileptic drugs used in epileptic patients. Pharmacy & Pharmacology International Journal, 7(3), 100–104. https://doi.org/10.15406/ppij.2019.07.00238
Nomura, S., Koizumi, H., Suehiro, E., Kiya, H., & Suzuki, M. (2016). Unique distribution of benzodiazepine receptors in the brain during the first two years of life. Pediatric Neurosurgery, 51(5), 244–248. https://doi.org/10.1159/000445903
Ogunrin, O. A., Adeyekun, A., & Adudu, P. (2013). Etiologies of epilepsy and health-seeking itinerary of patients with epilepsy in a resource poor setting: Analysis of 342 Nigerian Africans. Seizure, 22(7), 572–576. https://doi.org/10.1016/j.seizure.2013.04.012
Pavlou, E., & Gkampeta, A. (2011). Learning disorders in children with epilepsy. Child’s Nervous System, 27(3), 373–379. https://doi.org/10.1007/s00381-010-1321-9
Perucca, E., Covanis, A., & Dua, T. (2014). Commentary: Epilepsy is a global problem. Epilepsia, 55(9), 1326–1328. https://doi.org/10.1111/epi.12725
Perucca, P., Camfield, P., & Camfield, C. (2014). Does gender influence susceptibility and consequences of acquired epilepsies?
Powell, K. L., Fitzgerald, X., Shallue, C., Jovanovska, V., Klugmann, M., Von Jonquieres, G., O’Brien, T. J., & Morris, M. J. (2018). Gene therapy mediated seizure suppression in Genetic Generalised Epilepsy: Neuropeptide Y overexpression in a rat model. Neurobiology of Disease, 113(January), 23–32. https://doi.org/10.1016/j.nbd.2018.01.016
Ryvlin, P., Cross, J. H., & Rheims, S. (2014). Epilepsy surgery in children and adults. The Lancet Neurology, 13(11), 1114–1126. https://doi.org/10.1016/S1474-4422(14)70156-5
Sampaio, L. P. B., Caboclo, L. O. S. F., Kuramoto, K., Reche, Â., Yacubian, E. M. T., & Manreza, M. L. G. (2010). Prevalence of Epilepsy in Children From a Brazilian Area of High Deprivation. Pediatric Neurology, 42(2), 111–117. https://doi.org/10.1016/j.pediatrneurol.2009.09.002
Sampaio, L. P. B., Caboclo, L. O. S. F., Kuramoto, K., Reche, Â., Yacubian, E. M. T., & Manreza, M. L. G. (2010). Prevalence of Epilepsy in Children From a Brazilian Area of High Deprivation. Pediatric Neurology, 42(2), 111–117. https://doi.org/10.1016/j.pediatrneurol.2009.09.002
Socała, K., Szopa, A., Serefko, A., Poleszak, E., & Wlaź, P. (2021). Neuroprotective effects of coffee bioactive compounds: A review. International Journal of Molecular Sciences, 22(1), 1–64. https://doi.org/10.3390/ijms22010107
Steinmetz, S., Tipold, A., & Löscher, W. (2013). Epilepsy after head injury in dogs: A natural model of posttraumatic epilepsy. Epilepsia, 54(4), 580–588. https://doi.org/10.1111/epi.12071
Tan, M. (2014). Epilepsy in adults. Australian Family Physician, 43(3), 100–104. https://doi.org/10.1002/ana.410090103
Valentín, A., Morris, R., Honavar, M., Bodi, I., Teijeira-Azcona, A., Lázaro, M., Selway, R., Alarcón, G., & Richardson, M. P. (2015). Single pulse electrical stimulation identifies epileptogenicity in a case with subcortical nodular heterotopia and MRI negative epilepsy. Brain Stimulation, 8(3), 672–674. https://doi.org/10.1016/j.brs.2015.01.403
Wang, Mengjie, Ding, D., Zhu, G., Zhang, Q., Wang, T., Chen, Y., Wang, W., Hong, Z., Li, S., & Sander, J. W. (2019). Prevalence of epilepsy in rural China: A decreasing trend over 12 years. Journal of Neurology, Neurosurgery and Psychiatry, 90(11), 1289–1291. https://doi.org/10.1136/jnnp-2018-320131
Weckhuysen, S., Marsan, E., Lambrecq, V., Marchal, C., Morin-Brureau, M., An-Gourfinkel, I., Baulac, M., Fohlen, M., Kallay Zetchi, C., Seeck, M., De La Grange, P., Dermaut, B., Meurs, A., Thomas, P., Chassoux, F., Leguern, E., Picard, F., & Baulac, S. (2016). Involvement of GATOR complex genes in familial focal epilepsies and focal cortical dysplasia. Epilepsia, 57(6), 994–1003. https://doi.org/10.1111/epi.13391
Yuen, A. W. C., Keezer, M. R., & Sander, J. W. (2018). Epilepsy is a neurological and a systemic disorder. Epilepsy and Behavior, 78, 57–61. https://doi.org/10.1016/j.yebeh.2017.10.010
Zentner, J. (2012). Surgical treatment of epilepsies. In Acta Neurochirurgica, Supplement (Issue 84). https://doi.org/10.1007/978-3-7091-6117-3_3
Zhu, Q., Guo, Y., Ma, S., Yang, L., Lin, Z., Sun, H., Li, G., & Yu, L. (2021). Sociodemographic factors associated with the first administration of anti-seizure medication in patients with focal epilepsy in Western China. BMC Neurology, 21(1), 1–7. https://doi.org/10.1186/s12883-021-02282-w
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