Hepatoprotective action of vegetables
Keywords:
hepatoprotective, CCl4, paracetamol, hepatotoxicity, antioxidantsAbstract
India is a culturally diverse and traditional country. This region has its own set of dietary customs and medicinal practises. In India, a variety of traditional medical methods, including folk medicine, tribal medicine, Ayurveda, Siddha, and Unani, rely on herbal resources for therapeutic purposes. However, it has been discovered that most of the plants and their components, such as leaves, seeds, fruits and medicinal rooted substances contains antioxidants, flavonoids, tannins, and other phenolic compounds. Around 7,500 plants are said to be employed in the tradition of local health in rural and tribal regions in India. The true therapeutic efficacy of over 4,000 plants is either unknown or unknown to the general public. Around 1,200 plants are used in ancient medical systems like as Ayurveda, Siddha, Amchi, Unani, and Tibet. The liver plays an significant role in performance, maintenance and control of homeostasis in the body. It comprises a range of metabolic growth pathways, disease control, nutrition storage and supply. Additionally, it functions as a metabolic centre for the metabolism of nutrients such as proteins, lipids and carbohydrates, as well as the excretion of metabolic waste. Bile, which is secreted by the liver, plays a crucial function in digestion.
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Aga, M. Preventive effect of coriandrum sativum (Chinese parsley) on localized lead deposition in ICR mice. Journal of Ethnopharmacology. 2001, 2-3, 203-208.
Agarwal, M.; Srivastava, V.K.; Saxena, K.K. Kumar, A. Hepatoprotective activity of Beta vulgaris against CCL4- induced hepatic injury in rats. Fitoterapia. 2006, 77(2), 91-93.
Ansari, N.M.; Houlihan, L.; Pierni, A. Antioxidant activity of 5 vegetables- traditionally consumed by South Asian migrants in Bradford, Yorkshire UK. Phytother. 2005, 19, 907- 911.
Balamurugan, B.; Senthil Kumar, C.; Murugeswaran, S.; Natarajan, P.; Sharavanan, S.P.; Petchimuthu, S.; Thiru Senthil Murugan, S. Hepatoprotective Activity of Leaves and Roots Extracts of Moringa oleifera Lam. International Journal of Medicobiological Research. 2010, 1(2), 90-93.
Balasubramaniam, P.; Pari, L.; Venugopal, P.; Menon. Protective effect of carrot (Daucus carota L.) against lindane - induced hepatotoxicity in rats. Phytotherapy Research. 1998, 12(6), 434–436.
Bharali, R.; Tabassum, J.; Azad, M.R.H. Chemomodulatory effect of Moringa oleifera, Lam, on hepatic carcinogen metabolizing enzymes, anti-oxidant parameters and skin papillomagenesis in mice. Asia Pacific Journal Cancer Prevention. 2003, 4, 131–139.
Burdock, G.A.; Carabin, I.G. Safety assessment of coriander (Coriandrum sativum L.) essential oil as a food ingredient. Food Chem. Toxicol. 2008, 47, 22-34.
Chatterjea, M.N.; Rana Shinde. Liver function tests. In Textbook of Medical Biochemistry. Jaypee Brothers Medical Publishers Ltd. New Delhi 2005.
Ezeonwu; Valentine Ugonna. Hepatoprotective Activity of Bi-Herbal Ethanolic Extract of Phyllanthus Niruri & Moringa Oliefera on CCL4 Induced Hepatic Damage In Albino Rats. Asian Journal of Biochemical and Pharmaceutical Research. 2012, 3(2), 33-38.
Farooq Anwar; Sajid Latif; Muhammad Ashraf; Anwarul Hassan Gilani; Moringa oleifera. A Food Plant with Multiple Medicinal Uses. Phytotherapy research. 2007, 21, 17–25.
Gowtham, K.N.P.; Kuppast, I.J.; Mankani, K.L. A review on luffa acutangula. International journal of pharma world research. 2012, 3(1), 1-15.
Jadhav, V.B.; Thakare, V.N.; Suralkar, A.A.; Deshpande, A.D.; Naik, S.R. Hepatoprotective activity of Luffa acutangula against CCl4 and rifampicin induced liver toxicity in rats: a biochemical and histopathological evaluation. Indian J Exp Biol. 2010, 48(8), 822-829.
Jyothi, V.; Srinath Ambati; Asha Jyothi, V. The pharmacognostic, phytochemical and pharmacological profile of luffa acutangula. International Journal of Pharmacy & Technology. 2010, 2 (4), 512-524.
Kamel, B.S.; Blackman, B. Study of nutritional and oil characteristerics of the Luffa acutangula seeds. Food Chemistry. 1982, 9(4), 277-282.
Kanathur, N.; Mathai, M.G.; Byrd, R.P.; Jr, Fields, C.L.; Roy, T.M. Simvastatin-diltiazem drug interaction resulting in rhabdomyolysis and hepatitis. Tennessee Medicine, 2001, 94(9), 339-341.
Leena Kansal.; Veena Sharma.; Arti Sharma.; Shweta Lodi.; Sharma, S.H. Protective role of coriandrum sativum(coriander) extracts against lead nitrate induced oxidative stress and tissue damage in the liver and kidney in male mice. International journal of Applied Biology and Pharmaceutical Technology. 2011, 2(3), 65-83.
Mani Vasudevan.; Kumar Kishore Gunnam.; Milind parle. Antinociceptive and Anti-inflammatory Properties of Dacus carota seed extract. Journal of Health Science. 2006, 52(5), 598-606.
Nilesh, K.; Jain; Abhay, K.; Singhi. Protective role of beta vulgaris L. leaves extract and fractions on ethanolmediated hepatictoxicity. Acta Poloniae Pharmaceutica. Drug Research. 2012, 69(5), 945-950.
Pal, R.K. Hepatoprotective activity of alcoholic and aqueous extracts of fruits of Luffa cylindrica Linn in rats. Annals of Biological Research. 2011, 2, 132-141.
Ranju Pal; Kundlik Girhepunje; Hitesh Gevariya; Thirumoorthy, N. Hepatoprotective activity of Beta vulgaris against CCL4 induced acute hepatotoxicity in rats. Archives of Applied Science Research. 2010, 2(1), 14-18.
Ruckmani, K.; Kavimani, S.; Anandan, R.; Jaykar, B. Effect of Moringa oleifera Lam., on Paracetamol-Induced Hepatotoxicity. Indian Journal of Pharmaceutical Sciences. 1998, 60(1), 33- 35.
Samojlik, I.; Lakić, N.; Mimica-Dukić, N.; Daković-Svajcer, K.; Bozin, B. Antioxidant and hepatoprotective potential of essential oils of coriander (Coriandrum sativum L.) and caraway (Carum carvi L.) (Apiaceae). Journal of Agriculture and Food Chemistry. 2010, 58(15), 8848-53.
Shekhawat, N.; Soam, P.S.; Singh, T.; Vijayvergia, R. Antioxidant activity of 5 vegetables traditionally consumed by South Asian migrants. Indian Journal of Pharmaceutical sciences. 2010, 5(4), 298-301.
Shoba, S.; Patil, P.A.; Vivek, V. Hepatoprotective activity of Daucus carota (L) Aqueous extract against Paracetamol, Isoniazid and Alcohol induced Hepatotoxicity in Male wistar rats. Pharmacologyonline. 2008, 3, 776-787.
Sreelatha, S.; Padma, P.R. Antioxidant activity and total phenolic content of Moringa oleifera leaves in two stages of maturity. Plant Foods for Human Nutrition. 2009, 64(4), 303-311.
Tuse, T.A.; Harle, U.N.; Bore, V.V. Hepatoprotective activity of Colocasia antiquorum against experimentally induced liver injury in rats. Malyasian Journal of pharmacological sciences. 2009, 7(2), 99-112.
Vermeulen, N.P.E.; Bessems, J.G.H.; Van de streat, R. Molecular aspects of paracetamol induced hepatotoxicity and its mechanism based prevention. Drug Metab. 1992, 24, 367-407.
Yogeesh N. "Mathematical Maxima Program to Show Corona (COVID-19) Disease Spread Over a Period." TUMBE Group of International Journals, vol. 3, no. 1, 2020, pp. 14-16.
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