Comparative study of clinico-radiological pattern of patients with small cell and non small cell lung cancer
Keywords:
lung cancer, small cell lung cancer (SCLC), non small cell lung cancer (NSCLC)Abstract
Bronchogenic carcinoma is a malignant neoplasm of the lung arising from the epithelium of the bronchus. NSCLCs are a heterogeneous group, of which the most common subtypes are squamous cell carcinoma and adenocarcinoma. Squamous cell carcinomas are also predominantly linked to smoking. This study is planned to describe the clinical and radiological presentation of Small cell and Non-small cell lung cancer. The study included one hundred thirty patients admitted in various wards of hospital in chest Diseases and Tuberculosis & General Medicine department, at National institute of medical science & research, Jaipur between January, 2021 and December, 2021. Only those patients diagnosed as Primary lung cancer were included in this study. The present study included 130 proven cases of lung cancer. Two major histo-types of lung cancer SCLC and NSCLC were then correlated with their clinical and radiological features. 65 patients of each group were selected for study. Cough (with or without expectoration) was the common symptom (83.08%) observed in lung cancer patients. Chest pain was the next common symptom (80.77%) and had similar distribution in SCLC and NSCLC group patients. weight loss and Dyspnoea were the next common symptom observed.
Downloads
References
Jackman DM, Johnson BE. Small-cell lung cancer. Lancet 2005;366: 1385–1396.
Sakurai H, Asamura H, Watanabe S, Suzuki K, Tsuchiya R. Clinicopathologic features of peripheral squamous cell carcinoma of the lung.Ann Thorac Surg 2004;78:222–227.
Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002.CA Cancer J Clin 2005;55:74 –108.
Spiro SG, Silvestri GA. One hundred years of lung cancer. Am J Respir Crit Care Med 2005;172:523–529.
Pirozynski M. 100 years of lung cancer. Respir Med 2006;100:2073–2084.
International Agency for Research on Cancer. Tobacco Smoke and Involuntary Smoking, Vol 83. Lyon, France: IARC; 2002.
Thun MJ, Henley SJ, Calle EE. Tobacco use and cancer: an epidemiologic perspective for geneticists. Oncogene 2002;21:7307–7325.
Haussmann HJ. Smoking and lung cancer: future research directions.Int J Toxicol 2007;26:353–364.
Sasco AJ, Secretan MB, Straif K. Tobacco smoking and cancer: a brief review of recent epidemiological evidence. Lung Cancer 2004;45:S3–S9.
Jackman DM, Johnson BE. Small-cell lung cancer. Lancet 2005;366: 1385–1396.
Sakurai H, Asamura H, Watanabe S, Suzuki K, Tsuchiya R. Clinicopathologic features of peripheral squamous cell carcinoma of the lung.Ann Thorac Surg 2004;78:222–227.
Ehler, A., Stranahan, A. and Olson, K.B.: Bronchogenic carcinoma-A study of 517 cases. The new. Eng. J. Med. 1954: 251 :207-213.
Shankar, P.S. : Bronchogenic carcinoma Ind. J. Chest Dis. 1967: 9 : 161-164.
Nagrath, S.P. Hazra, D.K. Lahiri, B., Kishore B. and Kumar R. : Primary carcinoma of lung- Clinicopathological study of 35 cases. Ind. J, Chest Dis. 1970: 12 : 15-24.
Basu, B.K. and Gosh, T.N.: A study of bronchogenic carcinoma. Ind. J. Chest. Dis.1971; 13:1-9
Nafae, A., Mishra, S.P., S.N. and Shah A.S.N.: Bronchogenic carcinoma in Kashmir valley. Ind. J. Chest Dis. And allied Sci. 1973 : 15 : 285-292.
Jindal, S.K. Malik, S.K. Malik, A.K. Singh kartar, Gujral, J.S. and Sodhi, J.S. Bronchogenic carcinoma- A review of 150 cases. Ind. J. Chest Dis. 1979: 21 : 59-64.
Jain N.K., Madan, A., Sharma, T.N. Agnihotri, S.P., Devpura, G., Sarkar, S.K. and Jain D. : Bronchogenic Carcinoma- Histological diagnosis and roentgenographic relationship. Ind J. Chest, Dis. And Alli. Sci. 1987: 29 :192-197..
Cohen S., and Hossain, S.: Primary carcinoma of the lung- A review of 417 histologically proved cases. Chest 1966: 49:67-74
Jain, N.K. Madan, A. Sharma, T.N. Agnihotri, S.P. Saxena, A. and Mandhana,R.G. : Bronchogenic carcinoma- A study of 109 cases. JAPI 1989 : 37 : 379-382.
Jindal, S.K. and Behera, D.: Clinical spectrum of primary lung cancer- Review of Chandigarh experience. Lung India, 1990: 8 : 94-98.
Roswit B., Kaplan G and Jacobson, H.G.: The superior vena cava obstruction syndrome in bronchogenic carcinoma. Radiology 1953 : 61 : 722-736.
Hyde L. and Hyder C.I. : Clinical manifestations of lung cancer Chest 1974 : 65 : 299-306.
Selby H.M., Luomanen, R. and Sharma R.S.: The X- ray appearance of Oat-cell cancer of the lung Radiology 1963 : 81 : 817-823.
Byrd, R.B., Carr D.T. Millar W.E., Payne W.S. and Woolner L.B.: Radiographic abnormalities in carcinoma of the lung as related to histological cell type. Thorax 1969: 24 : 573-575
Sider. L.; Radiologic manifestation of primary bronchogenic carcinoma. Radio. Clin. North Am. 1990: 28 : 583-597.
Murray J.F. and Nadel J.A. : Text book of Respiratory Medicine. W.B. Saunder’s company, Philadelphia, 1994: 2nd Ed. : 1542-1544.
Fishman A.P., kotlof R.M.: Pulmonary disease and disorders- A companion book. McGraw Hill inc. New York, 1994: Second edition : pp. 232.
Jha, V.K. Roy, D.C. and Ravindran, P.: Bronchogenic carcinoma – A clinic pathologic study. Ind. J., Chest. Dis. 1972 : 14 : 78-85.
Sabour, M.S. : The radiologic appearance of lung cancer. The British J. Clinic Pract. 1964: 18 : 7-11.
Jindal, S.K. malik, S.K. Dhand, R. Gujral, J.S., Malik, A.K. and Dutta, B.N.: Bronchogenic carcinoma in Northern India. Thorax 1982: 37 : 343-347.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.








